DDS LAB_ QUIZ 1 Flashcards
LIQUID DOSAGE FORMS
- STERILE SOLUTIONS
- NON-STERILE SOLUTIONS
- SOLUTIONS
inserted directly to the body
STERILE SOLUTIONS
Example of Sterile Solutions
irrigation, nasal, optic, parenteral, ophthalmic
Example of non-sterile solutions
Mouthwash, Elixirs, Tinctures, Fluid extracts
Usually dissolved in water
Solutions
homogeneous solution
Solutions
Uniformity of doses
Solutions
Advantages of solutions:
- Easier to swallow (children, geriatrics, & unconscious)
- More quickly effective
- homogeneous
- dilute irritant actions
Disadvantages of solutions:
- Bulky for transport
- difficult to mask taste & odor
- needs an accurate spoon to administer drug
indicates the maximum concentration to which a solution may be prepared with that solvent
SOLVENT
concentrated solution
Saturated solution
No more solute can be dissolved
Saturated solution
Diluted solution
Unsaturated solution
More solute that can be dissolve
Unsaturated/Diluted solution
dissolving the solute
simple solution
reacting 2 or more solutes
solution by chemical reaction
like dissolves like
solution by extraction
a number of medicinal agents and provided in a dry powder or granule form
dry mixture
for reconstitution with a prescribe amount of water
dry mixture
mostly antimicrobials
reconstitution
solute is surrounded by solvent particles
solvation
very soluble
<1
freely soluble
1-10
soluble
10-30
sparingly soluble
30-100
slightly soluble
100-1000
very slightly soluble
1000-10000
practically insoluble
> 10000
Normal saline solution
0.9% or 0.9g NaCl in 100ml of water
important factor in determining the solubility of a drug and in preparing its solution
temperature
heating can facilitate solubility
Temperature