DDS LAB_ QUIZ 1 Flashcards

1
Q

LIQUID DOSAGE FORMS

A
  1. STERILE SOLUTIONS
  2. NON-STERILE SOLUTIONS
  3. SOLUTIONS
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2
Q

inserted directly to the body

A

STERILE SOLUTIONS

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3
Q

Example of Sterile Solutions

A

irrigation, nasal, optic, parenteral, ophthalmic

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4
Q

Example of non-sterile solutions

A

Mouthwash, Elixirs, Tinctures, Fluid extracts

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5
Q

Usually dissolved in water

A

Solutions

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6
Q

homogeneous solution

A

Solutions

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7
Q

Uniformity of doses

A

Solutions

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8
Q

Advantages of solutions:

A
  • Easier to swallow (children, geriatrics, & unconscious)
  • More quickly effective
  • homogeneous
  • dilute irritant actions
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9
Q

Disadvantages of solutions:

A
  • Bulky for transport
  • difficult to mask taste & odor
  • needs an accurate spoon to administer drug
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10
Q

indicates the maximum concentration to which a solution may be prepared with that solvent

A

SOLVENT

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11
Q

concentrated solution

A

Saturated solution

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12
Q

No more solute can be dissolved

A

Saturated solution

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13
Q

Diluted solution

A

Unsaturated solution

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14
Q

More solute that can be dissolve

A

Unsaturated/Diluted solution

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15
Q

dissolving the solute

A

simple solution

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16
Q

reacting 2 or more solutes

A

solution by chemical reaction

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17
Q

like dissolves like

A

solution by extraction

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18
Q

a number of medicinal agents and provided in a dry powder or granule form

A

dry mixture

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19
Q

for reconstitution with a prescribe amount of water

A

dry mixture

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20
Q

mostly antimicrobials

A

reconstitution

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21
Q

solute is surrounded by solvent particles

A

solvation

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22
Q

very soluble

A

<1

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23
Q

freely soluble

A

1-10

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24
Q

soluble

A

10-30

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25
Q

sparingly soluble

A

30-100

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26
Q

slightly soluble

A

100-1000

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27
Q

very slightly soluble

A

1000-10000

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28
Q

practically insoluble

A

> 10000

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29
Q

Normal saline solution

A

0.9% or 0.9g NaCl in 100ml of water

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30
Q

important factor in determining the solubility of a drug and in preparing its solution

A

temperature

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31
Q

heating can facilitate solubility

A

Temperature

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32
Q

weak acids or weak bases

A

pH of the solvent

33
Q

ex: alkaloids

A

weak bases

34
Q

ex: barbiturate drugs

A

weak acids

35
Q

weak base + strong acid

A

salt (soluble)

36
Q

weak acids + strong base

A

soluble salts

37
Q

4th major factors affecting solubility

A

various chemicals and other properties of both solute and solvent

38
Q

5th major factor affecting solubility

A

pressure

39
Q

6th major factors affecting solubility

A

particle size

40
Q

7th major factor affecting solubility

A

physical agitation

41
Q

2nd major factor affecting solubility

A

temperature

42
Q

1st major factor affecting solubility

A

solvent

43
Q

3rd major factor affecting solubility

A

pH of the solvent

44
Q

factors to consider in making solutions

A
  • solution pH
  • buffers
  • isotonicity
  • viscosity
  • preservatives
45
Q

Preservatives

A
  1. Effective against a spectrum of wide organisms.
  2. Stable
  3. Non-toxic; non-sensitizing
  4. Compatible w/ other ingredients
  5. Free of taste and odor
46
Q

Types of preservatives

A
  1. Acidic
  2. Neutral
  3. Mercurials
  4. Quarternary Ammonium Compounds
47
Q

Benzoic acid

What type of preservative?

A

Acidic

48
Q

used to inhibit oxidation

A

Antioxidants

49
Q

EDTA

A

ethylenediamine tetraacetic acid

50
Q
  1. sucrose
  2. polyhydric alcohols
A

Sweetening agents

51
Q

natural and parenteral resources

A

flavors & perfumes

52
Q

Oral solutions

A

Internal Solutions

53
Q

Parenteral Solutions

A

Internal Solutions

54
Q

Vaginal, Rectal, Oral, Nasal, Topical

A

External Solutions

55
Q

Solutions by simple solution

A
  1. Calcium Hydroxide Solution USP
56
Q

Calcium Hydroxide Solution USP

A

Lime hydrate/ caustic lime/ limewater

57
Q

protects against extraneous solids

A

Well-closed container

58
Q

protects from extraneous solids, liquids, or vapors

A

Tight container

59
Q

impervious to air or any gases

A

Hermetic container

60
Q

protects the contents from photochemical deterioration

A

Light resistant containers

61
Q

Astringent

A

Toner

62
Q

External

A
  • Astringent
  • Topical Protective
63
Q

Internal

A
  • Antacid
  • Calcium Supplement
64
Q

Strong Iodine Solution

A

Lungol’s Solution

65
Q

Thyroid crisis (storm)

A

Thyrotoxis

66
Q

a condition in which thyroid gland makes too much thyroid hormone

A

Hyperthyroidism

67
Q

Freezer

A

not exceeding 8 *c

68
Q

refrigerator

A

not exceeding 8*c

69
Q

cool

A

8c - 15c

70
Q

room temperature

A

20c - 25c

71
Q

controlled room temperature

A

0c - 15c

72
Q

warm

A

30c - 40c

73
Q

excessive heat

A

40*c and above

74
Q

Mild ticture/ weal solution of iodine

A

Iodine Tincture

75
Q

alcoholic or hydroalcoholic solution

A

Iodine tincture

76
Q

contains active principles of crude drugs

A

iodine tincture

77
Q

Betadine

A

Povidone Iodine Solution

78
Q

Anticoagulant Sodium Citrate Solution USP

A

parental products