Darovik CH 11 Flashcards
Metabolism of glucose produces what ?
Carbon dioxide - exhaled
Water - added to body’s water pool
Adenosine triphosphate (ATP) - energy
The amount of energy produced is determined by ?
The metabolic rate, amount of glucose, and amount of oxygen available.
When oxygen becomes unavailable or is inadequate, cells are forced to metabolize ———.
Anaerobically
Under anaerobic conditions, the amount of ATP generated is reduced to ——– and ——– rather than water and carbon dioxide is released by the cells.
97%
Lactic acid
Energy crisis and The accumulation of lactic acid are clinical evidence of what ?
Organ dysfunction/failure and metabolic acidosis.
The amount of oxygen normally consumed at rest is only about —– of the amount delivered.
25%
The amount of oxygen in mixed venous blood is about 75% of that of arterial blood. This is termed what?
Mixed venous reserve
Hypoxemia
PaO2 < 60 mmHg
Carbon monoxide poisoning
Methemoglobinemia
Hematopoetic problems
Aplastic anemia, the leukemias
3 Conditions that inhibit the cells from taking up/ utilizing oxygen.
Sepsis
Cyanide
Ethanol toxicity
Compensatory mechanism of increased cardiac output, how much can the average body compensate?
15 -25 l/m
Compensatory mechanism of increased oxygen extraction may drop the mixed venous oxygen saturation as low as 31% before what ?
Forced into anaerobic metabolism, termed drawing from the venous reserve.