Ch2 Pulmonary Anotomy and physiology Flashcards
Respiration
movement of gas molecules across cell membranes.
Ventilation
exchange of gas between lungs and the atmosphere.
What are the Four functional events of Cellular Respiration?
Ventilation
Distribution
Perfusion
Transport
The cyclic movement of the diaphragm and the structures of the thorax that results in the bulk movement of gases in and out of the lungs refers to what?
Ventilation
What is the primary ventilator muscle?
Diaphragm
Name the Accessory muscles of inspiration that cause the thorax to rise?
Scalene
trapezius
pectorlis,
Name the Accessory muscles of expiration?
Intercostals= pull ribs downward
abdominals = push diaphragm up
How many lobes does the Right lung have?
3
How many lobes does the Left lung have?
2
The mediastinal surface of each lung contains and area through which bronchi, pulmonary blood vessels, lymphatic vessels, and nerves enter and exit. What is it called?
Hilum
What lines the walls of the thoracic cavity?
Parietal pleura
What lines the outside of the lungs?
Visceral pleura
Pleural cavity?
Space between the parietal covered thoracic cavity and the visceral pleura covered lungs.
During spontaneous breathing what happens?
Negative intra-thoracic pressure draws air into the lung, and positive pressure blows it out.
Pressure cycled mechanical ventilation
Delivers air into airway until a set pressure is achieved.
Volume cycled mechanical ventilation.
Delivers air into airway until a set volume is achieved.
Time-cycled mechanical ventilation.
Delivers a volume of gas over a pre- set time.
Describe the mechanics of Inspiration during ventilation?
- > External intercostals contract which pull ribs upward and forward
- > Diaphragm contracts, descends and flatten
- > Lungs adhere to chest wall so the net result is a vacuum and air is drawn in
- > The negative intrathoracic pressure 755-757 mm Hg and air is drawn into the lungs. 5. > This also creates a vacuum for venous blood, which ↑ venous pressure.
Describe the mechanics of expiration during ventilation?
1.> Intercostals relax, diaphragm relaxes = dimensions are reduced resulting in > atmospheric pressure= exhalation.
CNS sensory neurons called “chemoreceptors” are located where?
What do they respond to ?
In or near the medulla oblongata in the CNS.
They respond to changes in H+ concentration or Pco2, or both in the CSF.
What does pCO2 stand for?
Partial Pressure of Carbon Dioxide
H+ ions are powerful stimulants to CNS chemoreceptors, but can not cross the blood: brain barrier. CO2 however, is highly permeable, so blood levels will quickly equilibrate in the CSF.
CO2 + H2O → H2CO3 → H+ + HCO3.
An increase in CO2 would also increase the H+ concentration which means a decrease in PH which makes a person acidotic.
Locations of Peripheral Nervous System Chemoreceptors?
Located in carotid (carotid bodies) and aortic arch. They transmit excitatory signals to the central respiratory center in the brainstem in response to low arterial oxygenation. (PaO2 60 - 30 mmHg)
Normal PaO2 ?
90-100 mmHg
Elevated PCO2 are characteristic of ?
COPD patients