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Pathology 2 > Cysts and Odontogenic Tumors 2 > Flashcards

Cysts and Odontogenic Tumors 2 Flashcards

1
Q

• Posterior jaws of teenagers, young adults
• Aggressive growth with 30% recurrence
• A unilocular or multilocular radiolucency; imitates other
lucencies

A

OKC

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2
Q

Where are OKCs mostly found in mouth? What age?

A

• Posterior jaws of teenagers, young adults

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3
Q
  • Primordial cysts 50%
  • Lateral periodontal 25%
  • Dentigerous 10%
  • Globulomaxillary 10%
A

OKC

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4
Q

Compact epithelium, no rete ridges, 8 to 10 cell layers thick
• Corrugated surface parakeratin
• Prominent, palisaded, hyperchromatic basal layer

A

OKC

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5
Q
  • Aggressive behavior
  • Recurrence - 30%
  • Nevoid Basal Cell Carcinoma Syndrome
A

OKC

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6
Q

• Syndrome-associated OKC –multiple OKCs common in the

_______

A

nevoid basal cell carcinoma syndrome

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7
Q

• Autosomal dominant - highly penetrant and variably
expressive
• Mutation in PTCH (PATCHED) tumor supressor gene at
9q22.3

A

nevoid basal cell carcinoma syndrome

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8
Q
  • Skeletal anomalies
  • Bifid ribs
  • Jaw cysts
  • Multiple OKCs
  • Skin tumors
  • Multiple, early onset basal cell carcinomas
  • Neoplasms
  • CNS –Medulloblastoma
A

nevoid basal cell carcinoma syndrome

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9
Q

Daughter cysts are seen in what disease process?

A

OKC

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10
Q

Ghost cells are seen in what disease process?

A

Calcifying Odontogenic cyst

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11
Q

• A developmental odontogenic cyst with an orthokeratin
lining, NOT parakeratin
• Originally described as the “orthokeratinized variant of the
odontogenic keratocyst”
• Does not behave as an odontogenic keratocyst
- no recurrence

A

Orthokeratinizing

Odontogenic Cyst

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12
Q
  • Gorlin cyst, calcifying and keratinizing odontogenic cyst
  • Anterior jaws of adults
  • Radiolucent to mixed
  • Ghost cells
  • Sometimes associated with
A

Calcifying Odontogenic Cyst
(Gorlin Cyst)
• WHO: Calcifying Cystic Odontogenic Tumor

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13
Q

Where in the mouth and what age are Calcifying Odontogenic Cyst
(Gorlin Cyst) seen?

A

Anterior maxilla of adults

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14
Q

• Sialodontogenic cyst –an odontogenic cyst with glandular
(salivary) features
• Anterior jaws of middle-aged adults, mandible > maxilla
• Commonly multilocular, crosses midline
• Aggressive behavior - 30% recurrence

A

Glandular Odontogenic Cyst

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15
Q

Can a lesion be an OKC with a mixed RO/ Radio lucent appearance?

A

No must be fully RL

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16
Q

• Soft tissue cyst of upper lip lateral to midline
• Developmental cyst, remnants of nasolacrimal duct
• Adult females (3:1)
-Moves the ala of nose

A

Nasolabial Cyst

• Nasoalveolar cyst, Klestadt cyst

17
Q
  • Cystic change of crypt epithelium of lymphoid aggregate
  • Young adults
  • Waldeyer’sring
  • Tonsillar pillar
  • Floor of mouth
  • Ventral tongue
A

Oral Lymphoepithelial Cyst

18
Q

• Cystic change of branchial epithelium
• Upper lateral neck anterior to border of sternocleidomastoid
muscle in young adults

A

Cervical Lymphoepithelial Cyst

• Branchial Cleft Cyst

19
Q
  • Cystic change of thyroglossal tract epithelium

* Midline of neck in young people

A

Thyroglossal Duct Cyst

20
Q

Histo of _______:
• Stratified squamous epithelial lining exhibiting lymphoid
tissue with or without germinal centers in wall

A

Cervical Lymphoepithelial Cyst

21
Q
  • Empty cavity - not a true cyst
  • Trauma-hemorrhage theory of origin
  • Male (2:1)
  • Teenagers –young adults
  • Mandible
  • Lucency
  • Scalloped border frequent
  • Asymptomatic
  • Expansion rare (20%)
  • Vital teeth
  • Biopsy initiates healing
A

Traumatic bone cyst

22
Q

Is root resorption ever seen in a traumatic bone cyst?

A

Never

23
Q
  • Young individuals < 20 years
  • Rapidly growing, may blow out the cortex, painful
  • Mandible most commonly
  • Lucency, frequently multilocular
A

Aneurysmal Bone Cyst

24
Q

Surgical Findings of ________:
• Ballooning dilation of bone
• Blood welling up from within the cavity, like a blood-soaked
sponge
• Fleshy aggregates of tumor surrounding cystic spaces filled
with blood
• Hemosiderin pigmentation

A

Aneurysmal Bone Cyst

25
Q

Histo of ______:
• Not a true cyst
• Cyst-like cavities, filled with blood
• Multinucleated giant cells

A

Aneurysmal Bone Cyst

26
Q
  • Asymptomatic
  • Radiolucency below inferior alveolar nerve canal
  • Submandibular gland
A

Stafne cyst

Pathology 2 (15 decks)

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