Cycles Flashcards

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1
Q

What are the two main phases?

A

follicular, luteal

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2
Q

What 2 phases can follicular be split into?

A

proestrus, estrus

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3
Q

What 2 phases can luteal be split into?

A

metestrus, diestrus

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4
Q

What is the difference between estrus and estrous?

A

estrus describes sexual receptivity (“heat”), estrous describes the cycle

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5
Q

What happens during proestrus? How long is it?

A

Drop in progesterone due to luteolysis, increase in FSH and LH and estradiol due to follicular maturation

2-5 days

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6
Q

What happens during estrus?

A

peak estradiol follicles due to dominant follicle
peak FSH, LH
ovulation

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7
Q

What happens during metestrus?

A

follows ovulation

ovulated follicle undergoing luteinization to CL

LH, FSH, estradiol, progesterone low (P increase at end)

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8
Q

What happens during diestrus?

A

high circulating progesterone is dominant
LH, FSH, estradiol low
important to support uterine endometrium for pregnancy
terminated with luteolysis

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9
Q

What are follicular waves?

A

multiple waves of follicular development that never reach completion because of inadequate hormone signals

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10
Q

What are the 3 phases of follicular development?

A

recruitment, selection, dominance

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11
Q

What happens during the recruitment stage of folliculogeneis?

A

entrance of cohort of antral follicles into gonadotropin-dependent stage

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12
Q

What happens during the selection stage of folliculogenesis?

A

reduction in number of recruited follicles to 1 follicle (or number of follicles that normally ovulate in that species)

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13
Q

What happens during the dominance stage of folliculogenesis?

A

inhibition of further recruitment and development of other follicles, this one grows to be ovulated or becomes atretic due to wrong stage

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14
Q

What is atresia?

A

follicle degeneration

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15
Q

What is spontaneous ovulation?

A

ovulate regularly after end of each follicular cycle
induced by ovarian steroids and gonadotropins
humans, sheep, cattle

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16
Q

What is induced ovulation?

A

go through follicular phase but ovulation occurs only after mating
neural stimulation due to mating causes a reflex release of LH
cats, rabbits, ferrets

17
Q

What are the steps of estrous synchronization?

A

suppression of HPG, restarting the cycle, advancing estrous

18
Q

What happens during suppression of HPG during estrous synchronization?

A

mimicking the presence of CL with progesterone (progestins)
progestins (MGA, CIDR) prevent LH surge and ovulation, suppresses uterine activity

19
Q

What is CIDR?

A

progestin
vaginal implant that secretes progesterone through vaginal wall lining

20
Q

What is MGA (melengestral acetate)?

A

progestin
feed supplement that binds progesterone receptors

21
Q

What happens during cycle restarting in estrus synchronization?

A

prostaglandin PGF2a
kill the CL so that estrus will occur 2-5d after

22
Q

What happens during advancing estrus during estrus synchronization?

A

GnRH
ovulates dominant follicles greater than 10mm
ovulation occurs 24-33h after