CVS Flashcards
What is the rate of diffusion limited by?
Area available for exchange Diffusion resistance - nature of barrier and molecules, path length Concentration gradient
What is capacitance?
Ability to cope with changes in cardiac output - a store of blood
Define flow
Volume of fluid passing a particular point per unit time Flow = volume/time (L/min-1)
Define velocity
The rate of movement of fluid particles along the tube Velocity = distance/time (m/min-1)
What is laminar flow?
Gradient of velocity from the middle to the edge of a vessel. Velocity is highest in the centre, fluid is stationary at edge
What is turbulent flow?
Velocity gradient breaks down due to increased mean velocity. Fluid tumbles over, increasing flow resistance
What is viscosity?
Extent to which fluid layers resist sliding over one another
What is the equation for resistance?
Resistance = Pressure/Flow
If flow is fixed, how does pressure change if resistance is increased?
Increase in pressure
If pressure is fixed, how does flow change if resistance is increased?
Decrease in flow
What is systolic pressure?
Maximum arterial pressure
What is systolic pressure affected by?
Heart contractility Total peripheral resistance Compliance of arteries
What is diastolic pressure?
Minimum arterial pressure
What is diastolic pressure affected by?
Systolic pressure Total peripheral resistance
What is pulse pressure?
Difference between systolic and diastolic pressure
What is equation to work our average arterial pressure?
= 2/3 diastolic pressure + 1/3 systolic pressure
Define total peripheral resistance
Sum of the resistance of all the peripheral vasculature in systemic circulation
What is the dicrotic notch?
Occurs when left ventricular pressure falls below aortic pressure and there is a subsequent backflow of blood closing aortic value