CVS Flashcards

1
Q

All of the following are true about secondary hypertension except?
Causes include artery stenosis,
Renovascular disease
Aortic coarctation
Pharmacologically resistance BP
Occurs in 90% of patients

A

Occurs in 90%

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2
Q

Systolic bp 120-139 is associated
50% increase risk of ________
71% increase risk of _______

A

Coronary heart disease
Stroke

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3
Q

These sites are the target of many anti hypertension drugs except
Heart
Kidney
Liver
Blood vessels
Medulla

A

Liver

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4
Q

In diabetic and renal disease patients BP goal is :
<120\80
<130/80
<115\75

A

B

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5
Q

Lowering bp lower the following risk factor by 20-25%
Stroke
Myocardial I
Heart failure

A

mI

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6
Q

Lowering bp lower the following risk factor by 40%
Stroke
Myocardial I
Heart failure

A

Stroke

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7
Q

Lowering bp lower the following risk factor by 50 %
Stroke
Myocardial I
Heart failure

A

Heart failure

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8
Q

Direct vasodilatory properties except
Indapamide
Furosemide
Amiloride

A

F

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9
Q

What diuretics isn’t useful in renal insufficiency?
Loop diuretics
Thiazide
K sparing
And which is useful

A

Unuseful .. thiazide
Useful loop diuretics

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10
Q

Following are true about thiazide diuretics except
A It requires normal renal and heart function
B require k supplements
C Metabolic effect is minimized if given in low doses
D Cause hypercalcemia, hypernatremia, hypokalemia
E in diabetic patients it increase blood sugar level

A

D

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11
Q

Diuretic that is rapid and short lived

A

Loop

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12
Q

High ceiling duiritc is ______
Used in acute cases _____

A

Loop

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13
Q

All are true about loop except
A Patients with severe ht
B Hypertension with hypovolemia
C Malignant hypertension
D Cause hypocalcemia and hypokalemia

A

B

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14
Q

Weak anti hypertensive diuretic is ____
Cause Hyperkalemia
And used with digitalis is ______

A

K sparing

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15
Q

Following are b blockers used in mild to moderate ht as 1st line agents except
A Propranolol
B celiprolol
C atenolol
D metoprolol

A

B

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16
Q

Most efficacious in low renin or volume expand hypertension is ______
Most efficacious in high renin ht is _____

A

Thiazide
B blockers

17
Q

Used in ht patients with MI, heart failure cop disease, reduce mortality
B blocker
A blocker
Ganglion blocker
Diuretics

A

Bb

18
Q

These beta blockers have vasodilating effect, alpha blocker effect which is effective in regressing or delaying organ damage except
A carvedilol
B celiprolol
D betaxolol
E nebivolol

A

D

19
Q

B blockers with intrinsic sympathomimetic activity except
A pindolol
B penbutolol
C acebutolol
D nadolol

A

D

20
Q

Following is true about intrinsic sympathomimetic drugs
A decrease BP with less deppresant effect of co or hr
B cause less bradycardia
C has withdrawal symptoms
D useful in patients with tachyarrhythmias, chf , vascular diseases
E both a and b

A

E

21
Q

All are side effects of b blockers except
A bradycardia
B bronchospasm
C Glucose tolerance
D withdrawal effects that cause increase bp

A

C

22
Q

Management of intraoperative and postoperative hypertension and ht emergencies
A Atenolol
B betaxolol
C esmolol
D metoprolol

A

C

23
Q

What do give to patients with ht and gout, bronchial disease, diabetes , hyperlipidemia
A doxazosin
B Prazosin
C atenolol
D trimazosin

A

B

24
Q

Alpha 1 blockers can be used in the following diseases except
A pheochromocytoma
B CHF ( to reduce preload
C BPH
D gout

A

B afterload

25
Q

drugs may cause orthodontic/ postural hypotension except
A a1 blockers
B methyldopa
C guanethidine
D minoxidil
E trimethaphan

A

D

26
Q

Block a and b except
A clonidine
B labetalol
C carvedilol
D nebivolol

A

A

27
Q

Useful for treatment of hypertension pheochromocytoma with no reflex tachycardia
A celiprolol
B labetalol
C prazocin
D terazosin

A

B

28
Q

Following drug has antioxidant effect, decrease endothelial damage and levels of highly atherogenic oxidized ldl cholesterol
A Nebivolol
B carvedilol
C clonidine
D methyldopa

A

B

29
Q

Has its primary use In treatment of chronic heart failure
A nebivolol
B carvedilol
C labetalol
D carteolol

A

B

30
Q

Drug used in renin dependent hypertension
A methyldopa
B carvedilol
C labetalol
D clonidine

A

D

31
Q

Hypertension in pregnant women is treated by
A clonidine
B methyldopa
C amphetamine
D methozamine

A

B

32
Q

All the following are SE of methyldopa except
A sedation , dry mouth , postural hypertension
B negative Coombs test, hemolytic anemia , hepatitis
C bradycardia
D Parkinsonian signs
E hyperprolactinemia

A

B

33
Q

Which is true about guanethedine
A doesn’t cause sympathoplegia
B reserved for severe/ resistant hypertension
C doesn’t cause postural hypotension
D blocked by NA reuptake blockers ( cocaine)
E B and D are correct

A

E

34
Q

Effects of reserpine on cns include all except
A sedation
B Parkinsonism like symptoms
C mental depression ( suicidal )
D all of the above

A

D