CVA Flashcards
Stats for ischemic and hemorrhagic stroke
Ischemic: 87%
Hemorrhagic: 13%
Mortality prognosis: 7/30/90 days
Higher mortality in hemorrhagic stroke
No difference after 3 months
Recurrence prognosis: 30 days/1 year/5 years/10 years
30 days = 3%
1 year = 11.1%
5 years: 25%
10 years: 40%
Cerebral thrombosis/embolism
Thrombosis - forms in the brain
Embolism - travels to the brain
Zone of injury: core ischemic + ischemic penumbra zones
Core ischemic - severe ischia with blood flow between 10-25% = death of neurons
Ischemic penumbra - regions surround severe, considered mild to moderate = where neuroplasticity is targeted
Crescendo TIA
2 occurrences within 24 hours
3 within 3 days
4 within 2 weeks
ABCD2 Prediction Rule
Age >60 years Blood pressure >140/>90 Clinical presentation - unilateral weakness with or without speech impairment OR speech impairment without weakness Duration >60 minutes OR 10-59 minutes Diabetes - higher score = more likely
Hemorrhagic risk factors
HTN
Alcohol and drug abuse
Use of anticoagulants
(not DM, obesity, previous stroke, oral contraceptives)
Saccular aneurysm
Roused or irregular swellings in arteries - commonly occurs at sides of vessel bifurcation
**>10 mm are at critical risk to rupture
Use of CT
Serves to rule out hemorrhagic stroke during initial evaluation of stroke; may identify ischemic lesion; ischemic lesion may not be detected in early hours after stroke
CT Angiogram
Provide clear images of cerebral blood vessels to allow identification of stenosis, occlusion, aneurysms, and vascular abnormalities
MRI
Detects edema in the sub-acute phase
More sensitive than CT scans but takes 1 hour to complete
Magnetic Resonance Angiogram
Can detect high grade atherosclerotic lesions and less common causes of ischemic stroke (vertebral after dissection, venous thrombosis, etc)
Positron Emission Tomograph (PET)
Imaging of regional blood flow and cerebral metabolism
**Used to determine the ischemic penumbra and where areas of tissue are reversible
tPA
Administered within 3 hours of sx onset (up to 4.5 hours in some patients)
MCA stroke
- Contralateral weakness (UE/face)
- Contralateral sensory impairment (UE/face)
- Aphasia
- Neglect
Lacunar stoke
- **Deep branches of MCA; supplying the BG and IC
- Contralateral weakness
PCA stroke
- *Supplies occipital lobe, inferior temporal lobe
- Contralateral homonymous hemianopsia
- Contralateral sensory impairment/weakness
ACA stroke
- *Primary motor/sensory, supplementary motor, prefrontal cortex
- Contralateral LE weakness/sensory
- Frontal lobe behavioral abnormalities (poor judgement, attention, motivation, regulating emotions)
Watershed strokes
- aka border zone infarcts
- occur at the border areas between vascular territory where the tissue is furthest from vascular supply and thus more venerable to reductions in perfusion.
- occur at distal branches of major cerebral arteries (MCA/ACA and MCA/PCA)
- Results from hypoperfusion
- Proximal arm and leave weakness with distal preservation of strength (man in a barrel syndrome)
- Tend to occur in the elderly, who have a higher incidence of arterial stenosis and hypotensive episodes, as well as microemboli.
- Can be associated with seizures , mild / progressive presentation
PICA stroke
- *Cerebellum and medulla
- LATERAL MEDUALLRY SYDNROME
- Loss of pain/temp on contralateral side of body and ipsi face
- Ipsi limb ataxia
- Dizziness/diploplia/dysphagia/dysarthria
- Horner’s syndrome
Horner’s syndrome
- *Damage to sympathetic trunk lateral to vertebral bodies
- associated with PICA strokes
- Ptosis (eyelid droop)
- Decreased sweating
- Miosis (pupil constriction)
- symptoms are same side
AICA stroke
- *Cerebellum and cranial nerves 7 and 8
- LATERAL PONTINE SYNDROME
- Ispi ataxia
- Contralateral weakness/sensory
- Dizziness/vertigo
Thalamic pain syndrome
- Initially presents as numbness but evolves into a burning sensation
- May be accompanied by allodynia
Visual tracts
Optic nerve - optic chiasm - opic tract - lateral geniculate nucleus - primary visual cortex
Right optic nerve lesion
Blindness of right eye
Optic chiasm lesion
Loss of temporal fields in both eyes = bitemporal hemianopsia