CV drugs

Question 1

Loop diuretics- Names

Answer 1

Furosemide, bumetanide

Question 2

Loop diuretics- MOA

Answer 2

Loop diureticd

Question 3

Loop diuretics- Indications

Answer 3

• Most powerful class

- HTN, CHF, edema

Question 4

Loop diuretics- AE

Answer 4

• Hypokalemia

- Volume depletion

Question 5

Thiazides- Names

Answer 5

• Hctz
• Chlorthaladone
• Metikazone

Question 6

Thiazides- MOA

Answer 6

• Prevent H2o, Na reabsorb

- DCT

Question 7

Thiazides- Indications

Answer 7

• Tx of choice for uncomplicated HTN

Question 8

Thiazides- AE

Answer 8

Hypo: K, Na,

- Caution in DM, gout

Question 9

K sparing diuretics- Names

Answer 9

• Spironolactone

- Amiloride, eplerenone

Question 10

K sparing diuretics- MOA

Answer 10

• Inhibit aldosterone mediated Na/H2O reabsorp

Question 11

K sparing diuretics- Indications

Answer 11

• W/ loops to retain K

- Weak diuretic

Question 12

K sparing- AE

Answer 12

Gynecomastia

Question 13

ACEI- Names

Answer 13

• “prils”

- Lisinopril, Captopril, enalapril

Question 14

ACEI- MOA

Answer 14

Decreased AG II/ aldosterone

- Decreases preload & after load

Question 15

ACEI- Indications

Answer 15

• 1st line tx for HF
• Cardio & renoprotective
• HTN

Question 16

ACEI- AE

Answer 16

• Cough & angioedema

- 1st dose hypotension

Question 17

ARB- Names

Answer 17

Losartan, valsartan

Question 18

ARB- MOA

Answer 18

Blocks Angiotensin

Question 19

ARB- Indications

Answer 19

• Unable to tolerate ACEI d/t AE

Question 20

ARB- AE

Answer 20

CI in pregnancy

Question 21

CCB- Names

Answer 21

• Nifedipine, amlodipine

- Verapamil, diltiazam

Question 22

CCB- MOA

Answer 22

• Vasodilation by blocking calcium channels

Question 23

CCB- Indications

Answer 23

• HTN- no effect on contraction or conduction of heart

- Angina

Question 24

CCB- AE

Answer 24

HA, dizziness, flushing

- Do not use with Beta blockers, CHF, heart blocks

Question 25

Beta blockers- Names

Answer 25

"olols" | - Propranolol, carvedilol, atenolol

Question 26

Beta blockers- MOA

Answer 26

- Block adrenergic renin release | - Catecholamine inhibitor

Question 27

Beta blockers- Indications

Answer 27

- MI, angina | - HTN, (not 1st line), caution in DM

Question 28

Beta blockers- AE

Answer 28

- Fatigue, depression | - impotence

Question 29

Alpha blockers- Names

Answer 29

"zosin" | - Prazosin, terazosin

Question 30

Alpha blockers- Indications

Answer 30

- HTN with BPH, hyperlipidemia | - Improves insulin sensativity

Question 31

Alpha blockers- AE

Answer 31

- 1st dose syncope | - Dizzy, HA

Question 32

Nitrates- Indications

Answer 32

- HTN emergency/ urgency, angina

Question 33

Nitrates- MOA

Answer 33

- NO release -> vasodilation - Increased myocardial blood supply - Reduced preload

Question 34

Nitrates- AE

Answer 34

HA

Question 35

Anti-arrhythmics- Types

Answer 35

- Na channel blockers - Beta blockers - CCB - K+ blockers- Amioderone - Digoxin

Question 36

Anti-arrhythmics- MOA

Answer 36

- Na: decreases conduction, prolongs repolarization - Beta/ CCB: Slow SA, AV node conduction - K+: Action potential prolongation - Dig: Inhibit ATPase- + inotrope

Question 37

Anti-arrhythmics- Indications

Answer 37

Na: Stable VT, narrow SVT - Beta/ CCB: A flutter, fib - K+: Atrial and vent arrhythmia - Dig: A fib, HF

Question 38

Adenosine

Answer 38

Anti-arrythmic - Block AV node conduction - DoC for SVT - Flushing, chest pain

Question 39

Mg sulfate:

Answer 39

DoC for torsades

Question 40

Direct vasodilators:

Answer 40

- Decrease after load - ACEI, ARBS - Beta blockers - Hydralazine + nitrates