CV anatomy+ blood Flashcards

1
Q

what is mediastinum and name the parts of mediastinum and what’s within?

A

mediastinum is an antomical region in the middle of the thorax (chest), bordered by the lungs on either side

superior
- upper: T1 and manubrium of sternum
- lower: sternal angle and T4/5
- aortic arch, trachea, oesophagus, thymus glands

inferior
- sternal angle to diaphragm
- anterior (fat and reminant of thymus)
- middle (heart)
- posterior (oesophagus, aorta)

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2
Q

name the layers of heart and what is it?

A

pericardium
1) fibrous layer
- tough outer, and anchor heart to diaphragm
- prevent overexpanding, and stop compression on hearts
2) serous layer
- parietal
- serious fluid in between
- visceral
myocardium
- muscle that controls contraction of heart
- with cardiac muscle cell
endocardium
- smooth lining to reduce friction and prevent blood clotting inside chamber

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3
Q

what is pipillary muscle?

A

muscle found in ventricle of hearts that anchor the chordae tendinae
- contract to tightening chordae tendinae, stablise valve

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4
Q

what is chordae tendinae

A

anchor valve to pipillary muscle in ventricle wall

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5
Q

what is the muscle found in ventricle and atria wall?

A

pipillary muscle (chordae tendinae)
pectinate muscle (allow stretch of atria)

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6
Q

what is trabeculae carnea?

A

round or irregular muscle column project from inner surface of ventricles

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7
Q

what is the round or irregular muscle column project from inner surface of ventricles?
–> spell

A

trabeculae carnea

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8
Q

what is the foetal feature describing the opening between RA and LA? and remnant name too?

A

foramen ovale
remnant: fossa ovalis

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9
Q

what is the foetal feature the allow blood to bypass liver? and remnant name

A

ductus venosus
ligamentum venosum

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10
Q

what is the foetal feature that allow blood to go from pulmonary artery (trunk) to aorta?

A

ductus arteriosus

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11
Q

what is auricle?

A

small, ear like muscular pouch in atria that allow atria to increase capacity when high pressure

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12
Q

name all the valve in heart and their location
whether they have chordae tendinae?

A

tricuspid, between RA and RV, have chordae tendinae
bicuspid/mitrial, between LA and LV, have
semilunar, pulmonary between RV and pulmonary artery, aortic between LV and aorta, don’t have

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13
Q

what is hole in heart? abd symptoms

A

atrial/ventricular/atrioventricilar septal defect

-cynosis, breathing problems, racing heart, weak pulse

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14
Q

what does the LUB DUB noice represent?

A

LUB: ventricular systole, closing of AV valve
DUB: atria systole, closing of semi lunar valve

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15
Q

the 2 level of coronary artery disease?

A

ischaemia
–> result in collateral circulation development
infarction
–> most common is anterior IV branch of LCA

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16
Q

what vein/artery is commonly used for coronary artery bypass grafting?

A

great saphenous vein
internal mammary artery

17
Q

name coronary artery and branches and where they supply?

A

from RCA
Marginal artery (anterior of RV)
Posterior interventricular artery (posterior interventricular sulcus, anastomes with anterior branch near apex)

from LCA
Anterior interventricular artery (anterior wall of both ventricles and septum)
circumflex artery (lateral and posterior of LV)

18
Q

name coronary vein and where they supply?

A

coronary sinus (main one)
anterior cardiac veins (directly from anterior of RV into RA, bypass sinus)

19
Q

component of blood and percentage

A

cells 45% (mostly RBC, WBC, platelets)
plasm 55%

20
Q

what is in plasma?

A

extracellular fluid, electrolytes, water, organic molecule,plasma protein

21
Q

name plasma protein and their uses?

A

albumin(60%): retain water in blood vessel, prevent edema, transport of lipids

globulin(35%): transport ions, hormones, lipids. immune function

fibrinogen(4%): blood clotting

regulatory protein (1%): hormones, enzyme

22
Q

what is the average blood volume in male and female?

A

60mL/Kg female
70mL/kg male

23
Q

size of RBC and features
lifespan, and how is it remove/broken down

A

6-8 micrometer
biconcave disc
120 days life span
breakdown by mononuclear phagocyte system (MPS)

24
Q

how is haem group in Hb brokwn down?

A

haem –> biliverdin –> bilirubin

25
in RBC formation, what main stuff happens and need what substance to support that?
1) reduction in size, and regression in nucleus - requires folic acid, and Vit B12 2) increase in haemoglobin content - requires iron
26
what hormones regulate RBC formation? and where is RBC formation?
regulate by erythropoietin in red bone marrow
27
describe haemoglobin structure and haem group structure?
globular protein, 2 alpha and 2 beta chain 4 haem group: have porphyrin ring and iron atom
28
describe the nucleus and staining of different WBC and relative size
Granulocytes eosinophil - stain pink - bi-lobed nucleus basophil - stain dark - bi-lobed nucleus neutrophil - multi-lobed nucleus Agranulocytes monocyte - largest - horseshoes shape nucleus lymphocytes - size varies - big nucleus
29
two types of antigen on RBC?
AB antigen Rhesus (RH) antigen
30
what is platelets derived from?
megakaryocytes
31
which side of diaphragm is higher? and why
right side, as the live is below it
32
what phrenic nerve supports diaphragm?
C345
33
describe structure of diaphragm?
musculotendinous structure muscle fibres arise radially from costal margins and converge to insert into the central tendon
34
what are these heart valve defect?
valve regurgitation - blood leaks back into chamber, when valve doesn't close tightly valve stenosis - thickening/stiffening of valve cusps, prevent valve from fully opening