Cutaneous skin masses Flashcards

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1
Q

Swellings of non-dermatologic origin

A
  • Hernias
  • Oedema
  • Bursitis
  • Emphysema
  • Mammary tumours
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2
Q

What is an oedema?

A

○ Ill-defined, soft, painless swelling from
○ E.g. R sided heart failure, hypoalbuminemia
○ Pits on pressure
○ Clear fluid on FNA

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3
Q

What is emphysema?

A

Sounds like crisp packet
Gas in subcutaneous tissue
Caused by:
□ Severe respiratory disease or lung puncture
□ Introduction of air through cutaneous wound
□ Rumenotomy or rumen cannulisation
□ Clostridial infections

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4
Q

Classifications of skin masses

A

Inflammatory
Neoplastic
Cystic

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5
Q

Inflammatory skin masses

A

○ Infectious
Bacterial infectious
Fungal infection
Demodex
○ Non-infectious
Urticaria/angioedema
Eosinophilic granuloma
Tick/insect bite granuloma
Sterile panniculitis
Haematoma
Seroma

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6
Q

Neoplastic skin masses

A

○ Epithelial neoplasm
○ Mesenchymal neoplasm
○ Round cell neoplasm

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7
Q

What is a cyst?

A

Cavity lined with epithelium which produces material into the cavity

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8
Q

Infectious Inflammatory Skin masses

A
  • Abscess/ cellulitis
    ○ E.g. post trauma/foreign body/ bite
    ○ Esp farm animal, cat. Also rabbits, secondary to dental disease
  • Furunculosis
    ○ E.g. staphylococcal deep pyoderma, Demodex
  • Bacterial granulomas
    ○ Mycobacteria
    ○ Actinobacillus, Nocardia, Actinomyces
  • Deep/subcutaneous or systemic fungal granuloma
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9
Q

Non-Infectious Inflammatory Skin masses

A
  • Urticaria, angioedema (esp horse> dog >cat)
    ○ Degranulation mast cells causing oedema
    Painless
    Pit on pressure
    ○ Can be allergic (type I or III) or non-immunologic cause
    ○ Urticaria = wheals (+/- pruritus)
    ○ Angioedema = large oedematous swelling, usually involving head – can be fatal
  • Seroma
    ○ Accumulation of serum under skin
    ○ Painless, non-pitting
    ○ Frequently occurs post-surgery
  • Haematoma
    ○ Loss of blood from damaged/ruptured blood vessels under skin
    ○ Painless, non-pitting
    ○ Usually due to trauma, occasionally to clotting problems
    ○ Others, e.g eosinophilic granulomas, tick/insect bite granulomas, sterile panniculitis
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10
Q

Neoplasms

A
  • Most commonly in older animals (a few exceptions)
  • Uncommon in farm animals
  • Horse
    ○ Especially melanomas (grey horses)
    ○ Sarcoids
  • Dogs
    ○ Skin neoplasms very common
    ○ E.g. lipomas, sebaceous adenomas, mast cell tumours
  • Cats
    ○ Neoplastic skin masses less common
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11
Q

Cysts

A
  • Epithelial-lined cavity, containing fluid or solid material produced by cells of cyst lining
  • Smooth, well-circumscribed
  • Fluctuant/solid
    ○ Dependent on nature of contents
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12
Q

How to decide what the mass is

A
  1. Signalment
  2. History – general, dermatological
  3. Clinical examination – general, dermatological
  4. Formulate list of ranked d/ds
    ○ Investigate d/ds using
    Cytology
    Tissue biopsy - histopathology +/- tissue culture
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13
Q

Signalment considerations

A

○ Species
E.g. abscess common in cat, cattle, rabbits
Skin neoplasms common in older dog
○ Breed/colour
E.g. Melanomas in grey horses
Mast cell tumours common in boxers
○ Age
Neonate – umbilical abscess

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14
Q

History considerations

A

○ General history
History of trauma/fight/surgery -> abscess/cellulitis, haematoma, seroma
Recent injection
□ Abscess, panniculitis
Systemic signs
□ Paraneoplastic
E.g. +/- haematemesis with mast cell tumour
□ Respiratory signs, weight-loss, lethargy
Systemic /metastatic neoplasia, systemic fungal infections
□ Depression, inappetance – some microbial infections/abscess
○ Dermatological history
Speed of onset of mass
Prior history of neoplasia?

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15
Q

General clinical exam considerations

A

Pyrexia
□ Often with systemic/severe cutaneous microbial infection, abscess
Peripheral lymphadenopathy
□ Metastatic spread of neoplasm, reaction to infection/inflammation
Other systemic abnormalities
□ May influence diagnostic/treatment choice
□ May link directly to mass
Animals with lung metastases may have no clinical signs
Non-dermatological swelling?
□ Bursa?
□ Joint swelling?
□ Hernia?

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16
Q

Dermatological exam considerations

A

Solitary/multiple lesions?
Area of body? Size?
Well-defined? Ill-defined?
Freely moveable?
Draining tracts/sinuses?
Pits on pressure?
Painful/painless?
Inflammatory?
Some neoplasms, e.g. mast cell tumour, can be associated with significant inflammation

17
Q

Types of samples for cytology

A

○ FNA
Generally most useful technique
‘Needle only’ with no suction
‘continuous suction’
‘Intermittent suction’
○ Impression smear of surface
○ Impression smear of sinus contents

18
Q

Limitations of cytology

A
  • Not all cell-types are shed easily
    ○ Not always representative/diagnostic
    ○ May take an unrepresentative sample
    ○ Gives no information on tissue architecture
    Can’t grade neoplasm
    Requires subsequent histopathology