cutaneous nocardia infection Flashcards
Rtio
nocardia
saprophytic gram positive anaerobic actinomyces
manifestation
Cellulitis. Inflammation 1 to 3 weeks following traumatic inoculation. Expanding erythema,induration; frm,non fluctuant. Untreated,infection can progress to involved adjacent muscles, tendons, bones, and joints. Dissemination is rare, and occurs in people with host dense defects. Nodular Lymphangitis. Begins as a nodule at the inoculation site. Untreated, infection extends into lymphatic vessels with linear subcutaneous nodules. CutaneousNocardiosis.Nodule occurs at the site of inoculation ,most commonly at the feet or hands. Untreated, infection expands forming plaques with sinus tracts and fistula or formation . As with eumycetoma, grains (dense masses or bacterial laments extending radially
from a central core)may be seen in discharging pus and tissue.After years,deformity of extremity may occur within involvement of adjacent anatomical structure.
Treatment
Trimethoprim/sulamethoxazole -preferred antimicrobial agent.
Minocycline or linezolid.
Surgical excision/debridement