Cat scratch disease

Question 1

Etiology and reservoir

Answer 1

Etiology.B.henselae

.Reservoir:Domestic cat

Question 2

Transmission

Answer 2

exposure to young cats

Question 3

demography/ age of onset

Answer 3

Children

Question 4

Pathogenesis

Answer 4

B.henselae causes granulomatous inflammation in healthy individuals(CSD)

angiogenesis in immunocompromised persons

Question 5

innoculation site

Answer 5

Innocuous-looking, small (0.5 to 1 cm) papule, vesicle, or pustule; may ulcerate; skin color pink to red; rm, at times
tender (Fig. 25-60). Residual linear cat scratch. Persists or1to3weeks.Distribution:Exposed skin o the ace and hands.

Question 6

Conjunctiva

Answer 6

3- to 5-mm whitish-yellow granulation

Question 7

Regional lymphadenopathy

Answer 7

within 2-3 weeks after inoculation in 90% of cases;primary lesion,is present,may have resolved by the time lymphadenopathy occurs.
Nodes are often solitary,moderately tender,and freely movable.Involved lymph nodes: epitrochlear, axillary, pectoral, and cervical.Nodes may suppurate.Usually resolved within 3 months.

Question 8

Treatment

Answer 8

In the immunocompromised, azithromycin; in immunocompetent, spontaneous resolution occurs