cutaneous manifestation of systemic disease Flashcards

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1
Q

4 categories of systemic disease

A

maker of internal disease
part of a multi system disease process
a marker of neoplasm
drug reaction

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2
Q

define necrobiosis lipodica

A

deep inflammatory reaction of the dermis

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3
Q

cause of necrobiosis lipodica

A

small vesle damage in diabetes

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4
Q

presentation of necrobiosis lipodica

A

yellow indurated plaques

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5
Q

common skin presentation of coeliac

A

dermatitis hepeteformis

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6
Q

what type of distribution is dermatitis hepeteformis and how does it present,

A

cape like (itchy, symmpeteical blister)

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7
Q

define calclyphylaxis

A

calcification of skin vessels.

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8
Q

what condition causes calclyphylaxis

A

chronic kidney disease

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9
Q

presentation of calclyphylaxis

A

star like eruptions

localised necrosis of overlying skin

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10
Q

define pyoderma gangerosum

A

necrotic skin condition resulting in deep ulcers

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11
Q

what cell type cause pyoderma gangerosum

A

neutrophils

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12
Q

what conditions is pyoderma gangerosum associated with

A

IBD, RA

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13
Q

define sarcoidois

A

mutisystem autoimmune granulomatous disease

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14
Q

skin presentation of sarcoidosis

A

gneralised plaque
erytherma nodusm
lupus pernio

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15
Q

presentation of SLE

A

malar photensetive rash
palmar eryhtema
facial disocid lupus

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16
Q

type of task in dermatomyositis

A

helitrope

17
Q

presentation of dermatomyositis

A

gouttrons

calcinosis

18
Q

presentation of acanthuses nigrcans

A

hyperpigmnetation in flexures

19
Q

what conditions is acanthuses nigrcans associated with

A

cancer

insulin resitance

20
Q

presentation of gouttrons

A

violcaeous plaques on knuckles

21
Q

what cells does necrolytic migratory erythema affects

A

a cells of pancreas

22
Q

presentation of necrolytic migratory erythema

A

excessive glucagon

23
Q

presentation erythema gyratum repens

A

wood grain

24
Q

presentation erythema annular

A

round lesions