Cushing Syndrome Flashcards
Collaborative Care
Goal of normalizing hormone secretion
Treatment dependent on cause
Surgical removal or radiation for pituitary adenoma
Adrenalectomy for adrenal tumours or hyperplasia
Ectopic ACTH- secreting tumours managed by treating primary neoplasm
Drug therapy indicated when surgery is contraindicated
Goal is inhibition of adrenal function
Collaborative Care: Mitotane
Suppresses cortisol production
Alters peripheral metabolism of cortisol
Decreases plasma and urine corticosteroid levels
Metyrapone, ketoconazole, and aminoglutethimide inhibit cortisol synthesis
Collaborative Care
If developed during use of corticosteroids
- Gradual discontinuance
- Reduction of dose
- Conversion to alternate-day regimen
Avoids potentially life-threatening adrenal insufficiency
Nursing Assessment: PMH
PMH
- Pituitary tumour
- Adrenal, pancreatic, or pulmonary neoplasms
- Frequent infections
Nursing Assessment
Use of corticosteroids Weight gain Anorexia Polyuria Prolonged wound healing Easy bruising Insomnia Back, joint, bone, and rib pain Amenorrhea Impotence Mood disturbances, anxiety, psychosis
Nursing Assessment
Truncal obesity Buffalo hump Moon faces Hirsutism of body and face Thinning of hair Thin, friable skin Acne Petechiae Purpura Hyperpigmentation Striae Hypertension Muscle wasting
Nursing Diagnoses
Risk for infection
Imbalanced nutrition: more than body requirements
Disturbed self-esteem
Impaired skin integrity
Nursing Planning
Client will:
- Experience relief of symptoms
- Have no serious complications
- Maintain positive self-image
- Actively participate in therapeutic plan
Nursing Implementation
Identify risk’s for Cushing’s syndrome
- Long-term exogenous cortisol
- Teaching r/t medications
Nursing Implementation
Assessment of S/S of hormone and drug toxicity, complicating conditions
- Cardiovascular disease
- Diabetes
- Infection
- Pathological fractures
Nursing Implementation
Monitor
- VS
- Daily weight
- Glucose
- S/S of infection
- Redness, fever may be minimal or absent
- S/S of thromboembolic phenomena
Nursing Implementation
Emotional Support
- May feel unattractive or unwanted
- Physical symptoms will resolve when hormone levels return to normal
Nursing Implentation
Pre-Op Care
- Hypertension and hyperglycaemia must be controlled
- Hypokalemia is corrected with supplements
- High-protein meals prevent depletion
Nursing Implentation
Teaching depends on surgical approach (include information on post-op care)
- NG tube
- Urinary catheter
- IV therapy
- Central venous pressure monitoring
- Leg compression devices
Nursing Implementation
Post-op
- Risk of hemorrhage is increased
- Manipulation of glandular tissue may release hormones into circulation
- BP, F&E tend to be unstable due to hormone fluctuations