Cardiovascular Disorders Flashcards
General Treatment Measures for Cardiac Disorders
Dietary Modifications - Decrease total fat intake - General weight reduction - Reduce salt intake Regular Exercise Program - Increases high-density lipoprotein levels - Lowers serum lipid levels - Reduces stress levels Cessation of Smoking - Decreases risk of coronary disease
Atherosclerosis
Diagnostic Tests - Serum lipid levels Treatment - Weight loss - Increase exercise - Lower total serum cholesterol and LDL levels by dietary modification - Reduce sodium intake - Control hypertension - Cessation of smoking - Antilipidemic drugs - Surgical intervention, such as coronary artery bypass grafting
Hypertension
Increased BP increases risk of: - Stroke - Ischemic cardiomyopathy - CAD Decreasing the BP by 5 mm/hg can reduce - Stroke by 34% - ICM by 21%
Treatment
Lifestyle Modifications
- Diet: Low Na+ DASH diet (rich in nuts, whole grains, fruits and vegetables), might require low fat as well
- Physical exercise/ stress reduction/ weight loss
- Restrict cigarette smoking, alcohol intake
Medication
- Biggest issue is side effects
- What meds given based on underlying diagnosis and comorbid conditions
- 1st line diuretics: Thiazides (no comorbid conditions)
- 2nd line ACE Is, ARB, Beta blockers, CCBs
Hypertension
Angiotensin-Converting Enzyme inhibitors/ Angiotensin II Receptor Blockers
Beta Blockers
CCBs
Diuretics
ACE Inhibitors/ ARBs
Used with pts with DM - helps to protect kidneys
ACEI - Inhibits enzyme in the body from making angiotensin II (vasoconstricts and increases BP)
- Ramipril (Altace), Enalapril (Vasotec), Captopril (Capoten), Benazopril (Lotensin)
ARB - block angiotensin II
- Candesarten (Atacand), Losartan (Cozaar)
Side Effects ACEI
- Angioedema - tongue and neck swell
- Cough 30% of the time - switch to ARB
- Inc K+, decrease Na+, increase CRS - can cause renal failure
Beta Blockers
Young Caucasian people with BP issues
Block effects of epinephrine (adrenaline)
- Carvedilol
- Metoprolol
- Atenolol
Side Effects
- Known response decrease HR, decrease BP
- Can increase lipids and cholesterol, increase depression, increase asthma and bronchospasm, increase K+
CCB
Works well for African American, elderly population
Affects movement of calcium into cells of heart and blood vessels, increase blood and oxygen, reducing workload
Vascular smooth muscle relaxation
Side Effects
- Dihydropyridine - nifedipine, amlodopine (only one that doesn’t cause HR to go up), cause peripheral vasodilation, HR goes up
- Edema, constipation, heart failure
- Non-Dihydropyridine - Diltiazem, Verapamil, cause reduction in inotrope - reduces contractility of heart, decreased HR
Diuretics
African American and elderly do well with diuretics
Thiazides
- Used as first line of treatment for individuals without other comorbid conditions (DM, HF, Hx of MI)
- Ascending limb
- Decrease K+, Na+, increase CRS
- Increase Ca+ (decrease amount excreted in urine), uric acid, lipids, glucose
Lassie
- Loop
- Decrease Ca+ (increase amount excreted in urine), K=, Na+
- Increase CRS
HTN Nursing Care
Ineffective health maintenance r/t noncompliance with prescribed treatment
- Teaching re medications, Na+ intake
- Lifestyle changes
- Weight loss strategies
Evaluation
Response to treatment - decrease BP
Teaching that still might be required - based on client responses to assessment
CAD
Treatment
- Main focus of CAD treatment is to lower LDL
Diet
- Low fat, low cholesterol to decrease lipid levels and promote weight loss
- Less than 7% saturated fats of total daily calories
- Cholesterol 25-35% of total calories
CAD: Medications
Therapy to lower total cholesterol and LDL levels Statins and diet first choice - Atorvastatin, Fluvastatin, Simvastatin - Inhibit cholesterol synthesis in liver - Lower LDL levels, some increase HDL - Side effects: Headache and GI effects - Myalgias (muscle aches) - Skin rashes - Liver function tests (LFTs) and muscle enzymes monitored for toxic effects
CAD
If combination of statins and diet not effective to lower cholesterol and LDL levels
Nicotinic Acid - Niacin
- Lower LDL and raise HDL
- Flushing, hot flashes and pruritus common side effects
Bile Acid Sequestrants - Cholestyamine, Colestipol
- Bind with bile acids and cholesterol in intestine, excrete in feces
- GI side effects: constipation, gas, abdominal cramping
Medications
ACE Is Beta Blockers CCBs Diuretics Will depend on comorbid conditions and extent of disease