Current Issues - Emerging & Endemic Disease Flashcards
What is monkey pox?
a viral illness caused by the monkeypox virus, a species of the genus orthopoxvirus
When did monkeypox show up in the US and how?
2003 - Midwest
came in from pets being imported like Gambian rats
Who is most at risk for monkeypox? How is it spread?
gay, bisexual, or other men who have sex with men
sex
T/F: Monkeypox straight from monkeys is significantly fatal
TRUE
What organization declares public health emergencies that triggers requirements in other countries?
WHO
What is Alpha-gal syndrome?
red meat allergy - serious
most often in adults bitten by certain types of ticks
not super rare
77% of all vector borne diseases in the USA are mediated by ______
ticks
What is the history of Alpha-gal syndrome?
What is the pathogenesis of Alpha-gal syndrome?
during feeding, tick salivary secretions modulate host immunity and inoculate pathogens and antigens
triggers life-threatening IgE-mediated hypersensitivity (3-6 hours after ingestion)
Alpga-gal syndrome has [immediate/delayed] anaphylaxis
delayed
Where are the places where people had delayed anaphylaxis to red meat whose serum contained IgE antibodies to alpha-gal?
Oklahoma
Missouri
Arkansas
TN
Mississippi
GA
NC
VA
Maryland
Which tick is a mediator of Alpha-gal?
lone star tick - we all have antibodies but we don’t all have the tick salivary secretion trigger
[Males/Females] are more affected by AGS
males
Does everyone have antibodies for AGS?
yes - but some do not react
How do you treat and prevent AGS?
no specific treatment or cure
no preventative therapies