cumulative part fo 439B final Flashcards
papule
elevated round <1 cm
plaque
palpable, elevated, depressed, >1cm
macule
flat, non-pal <1cm
patch
flat, >1cm (interchange with plaque)
vesicle
fluid filled <1cm
bullae
fluid filled >1cm
postules
pus filled vesciles
urticaria
wheals/hives, elevated, red ,pruiritic lesions
nodule
firm, palpable, extend into dermis or sq tissue
scale
scaley
crust
crust
petechiae
pinpoint non-blanchable red purple spots
telangiectasia
spider veins
risk facotrs SCC
elderly and Caucasian cumulative UV exposure fair skin male >50 YO inflammatory skin DO exposure to carcinogens HPV infection immunosuppression (transplant pts)
Immunosupression transplant pts in SCC
65 fold increase risk
more aggressive and freq metastases than traditional SCC
actinic keratosis
chronic UV exposure
rough, scaly plaques
<1 % progress to SCC
topical or cryo
bowens disease
chronic sun exposure or viral infection like HPV 16 or 18
up to 25% can become invasive SCC into dermis
red brown plaque with crusted scale
tx sx chemo or cryo
SCC metastases
2-6%
SCC variants
keroacanthoma- can regress- resembles SCC
verrucous carcinoma- giant warts
marjolins ucler- AGGRESSIVE, scc developing from ulcer or wd
Mucosal SCC- more aggressive than usual scc 20-70% mets
BCC risk factors
elderly and caucasians austrilians hihg UVB exposure ionizing radiation (xray ) exposure exposure to carcinogenic chemicals genetic syndromes
s&S BCC
pearly nodule, head and neck with CENTRAL ucler
- can be pigmented, raised, shiny pearly borders
BCC tx
biopsy if suspicious-refer to derm curettage/electo <1cm, cure 95% cryosurgery- cure 90% topical chemo- 75% (superficial BCC only) radiation- 80% surgical excision ** gold** 95%c cure mohs micrographic surgery (for aggreesive BCC) cure 95% vemuragenib - local chemo
fragility fx
low trauma fall from standing height or lower that occurred during injury
Plaquenili
- photosensitivity renal issues- renal toxicity opthlamology at baseline skin changes n/v/ tinnitus -continue dose even with SE tx lupus
OA and RA on xray
RA has erosion of bone, OA shows osteophytes, malalignment, bone on bone (narrow space)
xray may NOT correlate with s&S
plantar fascilitis
painful DO involving plantar aspect of heel
acute or chronic
-point tenderness
tx rest, footwear, NSAIDS, ice, massage