CT - Structural Elements (Fibres)

Question 1

What proteins produce collagen and reticular fibres ?

Answer 1

Collagen

Question 2

What proteins produce elastic fibres ?

Answer 2

Elastin

Question 3

What type of collagen fibres are fibrillar collagens

Answer 3

Type I
Type II
Type III

Question 4

What is type I collagen response in the production of ?

Answer 4

Skin
Tendon
Bone

Question 5

What is type II collagen response in the production of ?

Answer 5

Cartilage

Question 6

What is type III collagen response in the production of ?

Answer 6

Skin
Muscle
Blood vessels

Question 7

What type of collagen is network or sheet-forming

Answer 7

Type IV

Question 8

What is type IV collagen response in the production of ?

Answer 8

Basal lamina

Question 9

What type of collagen is linked / anchoring ?

Answer 9

Type VII

Question 10

What is type VII collagen response in the production of ?

Answer 10

Epithelial basement membrane

Question 11

What chain beings collagen assembly?

Answer 11

3 Precursor alpha chain

Question 12

What enzyme cleves the none helical terminal ends of the pro collagen ?

Answer 12

Pro collagen peptidase

Note - this produces tropocollagen

Question 13

What can collagen fibrils do?

Answer 13

Assemble together to form the collagen fibre

Question 14

Where can elastic fibres be found ?

Answer 14

The dermis
Elastic arteries
Lungs
Some cartilage

Question 15

What surrounds the elastin core of the elastin fibres and what are they made up of?

Answer 15

Microfibrils - made up of a glycoprotein called fibrolin

Question 16

What do we stain reticular fibres with?

Answer 16

Silver salts

Question 17

Where are reticular fibres found ?

Answer 17

In delicate CTs - e.g. the immune system

Question 18

How are reticular fibres formed ?

Answer 18

They are highly glucosalyated and these sugar chains bind to the type III collagen