Cryptosporidium, Microsporidium, Isospora Flashcards

0
Q

What is Cryptosporidium parvum?

A

A protozoan parasite.

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1
Q

What is cryptosporidium caused by?

A

Cryptosporidium parvum.

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2
Q

How is Cryptosporidium parvum spread?

A

Oocysts shed in faeces therefore faecal-oral route.

*low-grade contamination Eg) recreational water

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3
Q

Characteristics of Cryptosporidium parvum oocysts?

A

Can survive for long periods in the environment.

Resists disinfection including chlorination.

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4
Q

What is Cryptosporidium parvum a cause of?

A

Mild self-limited Diarrhoea - immunocompetent
Persistent Diarrhoea - children in developing countries
Severe Diarrhoea - AIDS patients *50 stools a day

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5
Q

How to diagnose Cryptosporidium parvum?

A

See Oocysts in faeces.

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6
Q

How to avoid Cryptosporidium parvum?

A

Difficult to eliminate form water supplies due to resistence to disinfection.
AIDS sufferers to boil their water and avoid obvious sources of possible infection.

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7
Q

Treatment for Diarrhoea caused by Cryptosporidium parvum?

A

No totally effective treatment.
Supportive therapy > fluid + electrolyte replacement.
Antiretrovirals in immunodeficiency.

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8
Q

Causative organism of Isospora?

A

Isospora bell

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9
Q

What does Isospora bell cause?

A

Severe/chronic Diarrhoea.

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10
Q

Which group of people does Isospora bell cause Diarrhoea in normally?

A

Immunocompromised.

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11
Q

How to diagnose Isospora bell?

A

See oocyts on faeces.

Auramine stains can be used.

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12
Q

Treatment for Isospora bell infection?

A

Co-trimoxazole.

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13
Q

What kind of organism is Isospora bell?

A

Similar to Cryptosporidium parvum. Parasitic protozoan.

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14
Q

What kind of organism is Microsporidium?

A

Related to fungi.

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15
Q

What does Microsporidium cause wand who are at risk?

A

Causes Diarrhoea and wasting in the immunocompromised (AIDS patients).

16
Q

How to diagnose Microsporidium?

A

Oocysts in faeces on wet prep.

17
Q

How to treat Microsporidium?

A

Albendazole.

Antiretrovirals to combat immunodeficiency.