Critical Care Flashcards
Epistaxis - complications of cautery
- Septal perforation
- Staining of silver nitrate
- Secondary bacterial infection
Epistaxis - complications of packing (try for x8)
- Pressure necrosis
- Pain, discomfort
- Airway compromise
- Neurogenic syncope
- Septal hematoma, ulceration, perforation
- Synechiae/adhesion formation
- Rhino-sinusitis infection
- TSS
Indications to transfuse platelets?
- <100 for CNS bleed or CNS surgery
- <50 if actively bleeding or undergoing major surgery or unstable NAIT
- <10 for prophylactic treatment
Indications for pRBC transfusion?
- Acute blood loss of >15% of total blood volume
- Hb <70 with symptoms of anemia
- Significant pre-operative anemia without other corrective options available
- Hb <130 on ECLS
- Chronic transfusion program for disorders of RBC production
Decision to CT for head injury - rules to use and absolute/relative indications.
Rules: PECARN, CATCH
Absolute: focal neuro deficit, suspected or diagnosed open/depressed fracture
Relative: GCS <14 initially (or GCS <15 at 2h post), clinical worsening 4-6h, boggy/large hematoma, basal skull fracture signs, mechanism, seizures, persistent irritability, known coagulopathy
Pharmacological management of status epilepticus (include doses)
First line: midaz IN/IM (0.2 mg/kg), lorazepam IV (0.1 mg/kg)
Second line: keppra 60 mg/kg, fospheny/pheny 20 mg/kg, phenobarb 20 mg/kg (for <6 months)
Cardiac manifestations of TCA toxicity, including mechanism
Due to ability to block fast Na channels
- sinus tachycardia
- widening of QRS complex
- PVCs
- ventricular dysrhythmias
- hypotension
Rx for widened QRS secondary to TCA toxicity?
Na bicarb
Med to give in refractory VF (including dose)
Amiodarone 5 mg/kg
How to check tetany in hypocalcemia?
Chvostek - tapping face
Trousseau - BP cuff
VT with pulse - what to do with hemodynamic compromise?
Synchronized cardio version
Epi dosing for anaphylaxis and cardiac arrest
Anaphylaxis: 0.01 ml/kg of 1 mg/ml
Cardiac: 0.1 ml/kg of 0.1 mg/ml
Parkland formula
What fluid to give?
4ml x kg x %BSA = first 24 hours
Divide by 1/2 for the first 8 hours
Add maintenance if patient <30kg
Ringer’s lactate
What bacterial pneumonia is associated with RSV?
Pneumococcal pneumonia
Jimson weed - purple flower
Anti-cholinergic
Antidote for benzo overdose
Flumazenil
Iron toxic ingestion - medication, next step
Give activated charcoal?
Deferoxamine
Whole bowel irrigation
ETT x2 equations
Uncuffed: age/4 +4
Cuffed: age/4 + 3.5
Min SpO2 for bronchiolitis
90
How do you differentiate serontonin syndrome vs neuroleptic malignant syndrome?
Rigidity in NMS
Sympathemetic vs anti-cholinergic
AC - pupils slow to react, dry, bowel sounds decreased
Anticholinergic - toxins
Anti-histamines, atypical antipsychotics, Jimson weed, TCAs
What size of needle to use for pneumothorax?
18 gauge angiocath
What RSI medication is contraindicated for burn patients?
Succinylcholine
Signs of inhalation injury
Burns involving face/neck, singeing of eyebrows/nasal hairs, hoarseness/stridor, sings of parenchymal involvement
First management for CO poisoning
Initiate 100% FiO2 through NRM
Signs on examination of when to consider intubation for upper airway obstruction?
- Muffled/hot potato voice
- Inability to control secretions
- Stridor
- Dyspnea
Dx for patient with upper airway obstruction + trismus
Peritonsilar abscess
Steeple sign
Croup
Thumb printing
Epiglottitis
Brassy cough
Bacterial tracheitis
Minimal oxygen supplementation for age (L/min)
<1 yr = 2 L/min
1-5 yr = 4 L/min
5-10 yr = 6 L/min
>10 yr = 8 L/min
Most respiratory cause of ARDS and most common non-respiratory cause of ARDS
Resp = PNA Non-resp = sepsis
Why is intubation avoided in asthma patients - x2 pathophysiology reasons?
Hemodynamic instability
FB in airway can cause further bronchospasm
What is the normal range for SVO2?
70-75%
x3 signs of uncompensated shock
- Hypotension
- Altered LOC
- Oliguria
Better to push bolus through central or peripheral line
Peripheral
SIRS criteria
Require 2 of the following - with one being temperature or WBC:
- Temperature instability
- Tachycardia/bradycardia
- Tachypnea
- Leukopenia/leukocytosis
Sepsis = definition
SIRS + suspected/confirmed infection
What dosing range will you have more beta effect vs alpha effect for epi?
Beta - low dose
Alpha - high dose
What is the one VS derangement do we want to avoid the most with TBI patients?
Hypotension
What should our ICP be below in setting of TBI?
<20 cm H20
CPP targets for age to maintain ICP thresholds
Infants/toddlers = >40 Children = >50 Adolescents = >60
Steps (x3) to address increased ICP
- Hyperosmolar therapy
- Analgesia + sedation
- Neuromuscular blockade
What could you give in rhabdo with anuria?
Mannitol infusion
Difference between costochondritis vs Tietze Syndrome
Costo = multiple costochondral + costosternal junctions, no swelling typically. Tietze = more localized form with discrete area of swelling
Airway differences between children and adults
- Large occiput
- Large tongue
- Floppy epiglottis
- Anterior/cephalad larynx
- Narrow subglottic airway
Fasting guidelines
- Clear fluids 1 hour
- Human milk 4 hours
- Formula, light meal, non-human milk 6 hours
ASA - basic ideas for anesthesia
- ASA I = healthy
- ASA II = mild systemic disease
- ASA III = severe systemic disease
- ASA IV = constant threat to life
- ASA V = not expected to survive 24 hours
Emergency equipment to have at bedside for procedural sedation
SOAPME:
- Suction
- Oxygen
- Airway equipment
- Positive pressure system (BVM)
- Monitors
- Emergency cart
PECARN absolute rules for CT
<2 years = GCS<15, AMS, palpable skull fracture
>2 years = GCS<15, AMS, signs of basilar skull facture
PECARN intermediate factors for CT
<2 years = emesis, LOC >5s, irritable, severe mechanism of injury
>2 years = emesis, LOC >5s, worsening HA, severe mechanism
Causes of elevated AG metabolic acidosis
MUDPILES:
- Methanol
- Uremia
- DKA
- Paraldehyde
- IEM, iron
- Lactic acidosis
- Ethanol, ethylene glycol
- Salicylate
2 main categories + causes for primary metabolic alkalosis
- Saline responsive: pyloric stenosis, GI loss (emesis), laxative/diuretic use, CF, Cl deficient infant formula
- Saline resistant: hyper-reninemic HTN, CC’s, K deficiency, genetic block of steroid synthesis (17-OH def), renal dysfunction (Bartter, Gitelman, Liddle syndrome(
x4 side effects of ventolin
- Tachycardia
- Hyperglycemia
- Hypokalemia
- Lactic acidosis
x2 side effects of MgSO4 in asthma exacerbation
- Hypotension
- Bradycardia
Equation to calculate size of ETT for cuffed + uncuffed
- Uncuffed: age/4 + 4
- Cuffed: minus 0.5
MOA of ketamine
- NMDA receptor antagonist
- Dissociative analgesia, sedation + amnesia
- Bronchodilator
SE and contraindication for ketamine
- SE: hypotension, increased secretions, hallucinations
- Contraindication: hx of anaphylaxis, cardiac sensitivity to catecholamine surge (myocarditis)
Is PUD a common cause of abdominal pain for CF?
No
Clinical presentation of cholinergic toxidrome
=DDUMBELLS!
- Diaphoresis
- Diarrhea
- Urination
- Miosis
- Bronchorrhea
- Emesis
- Lacrimination
- Lethargy
- Salivation
x3 categories/examples of cholinergic toxins
- Organophosphates: insecticides
- Carbamates: neostigmine, pyridostigmine, pesticides
- Alzheimer’s medications
Difference in MOA between (a) organophosphates and (b) carbamates?
Both bind/inhibit acetylcholine esterase
(a) irreversibly
(b) transiently
Management of cholinergic intoxication
Supportive:
- Supplemental O2
- ETT if needed (avoid succhinycholine)
- IVF
- Benzos (for agitation/seizures)
Decontamination:
- Remove all clothes
- Irrigate skin
- Wear PPE
Treatment:
- Atropine 0.05 mg/kg IV/IM/IO bolus q5min until secretions improved
- Pralidoxime (pries pesticide off anticholinergic receptors)
- Inhaled atrovent
Clinical presentation for anti-cholinergic toxidrome
=Opposite DDUMBELLS
- Hyperthermia, flushed
- Decreased bowel sounds
- Dry skin + mouth
- Decreased urination
- Mydriasis
- Confused
If you are seeing an anti-cholinergic toxidrome, what is the most important Ix to consider?
ECG - to see if widening QRS as a clue for TCA overdose
Examples of toxins that would present with anti-cholinergic toxidrome
- Atropine, cyclopentolate
- Scopolamine, glycopurrolate
- Antihistamines
- Jimson weed
- Neuroleptics (olanzapine)
- TCA