Cranial Nerves Flashcards
What is CN I?
The olfactory nerve
Responsible for smell from nasal mucosa
How does CN I exit the skull?
Cribriform plate
What fibre type does CN I carry?
Special sensory - olfaction
What symptoms present with damage to CN I?
- Anosmia (loss of sense of smell)
- Parosmia (distortion of smell)
- Olfactory Hallucination
What is CN II?
The optic nerve
Responsible for vision from retina
What fibre type(s) does CN II carry?
Special sensory - vision
What does CN II innervate?
The retina
How does CN II exit the skull?
The optic canal
How can you test CN II?
- Visual acuity
- Fundoscopy
- Pupil light reflex
- Accommodation and visual fields
Give examples of conditions that could cause issues with the retina
- Papilloedema
- Retinopathy
- Emboli
- Haemorrhage
- Scar
What is the principal of the consensual light reflex?
Shining light in one eye should make both pupils contract
What does the Pupillary light reflex test?
The function of the retina, CN II, the midbrain and CN III
What is CN III?
The oculomotor nerve
Responsible for motor to superior rectus, inferior rectus, medial rectus, inferior oblique and levator palpebrae superiororis
Also responsible for parasympathetics to sphincter pupillae and cilliary muscle (constricts pupil and helps with accommodation of lens)
What fibre type(s) does CN III carry and where do they synapse?
Somatic motor - Oculomotor nucleus (CN III motor nucleus midbrain)
Visceral motor - Edinger-Westphal nucleus in the midbrain
How does CN III exit the skull?
Via the Superior Orbital Fissure
Does the oculomotor nerve pass through the cavernous sinus?
Yes
What is the cavernous sinus?
A venous sinus (2 pockets of venous blood) on either side of the sella turcia (the saddle where the pituitary gland sits)
Describe CN III fibres route from their brainstem nuclei
Both motor and parasympathetic fibres exit the brainstem together via the interpeduncular fossa, they then pass through the cavernous sinus and the superior orbital fissue to the eye
Give examples of lesions that can damage CN III
- Midbrain lesions
- Interpeduncular fossa lesions
- SCA or PCA aneurysm
- Cavernous sinus lesions
- Ischaemia
What would be the clinical presentation of a CN III lesion?
- Dilated pupil unresponsive to light and accommodation
- Complete ptosis on affected side
- Eye is down and out
- Diplopia
What is CN IV?
Trochlear nerve
Responsible for motor to superior oblique (turns eye down and out)
What fibre type(s) does CN IV carry?
Somatic motor
Where does CN IV synapse?
The midbrain, trochlear nerve nucleus
How does CN IV exit the skull?
Via the superior orbital fissure
What does CN IV provide innervation to?
Motor to the superior oblique muscle
How would damage to CN IV present?
A resting eye that has an upward deviation and extorsion (outward rotation)
What is CN VI?
The abducens nerve
Responsible for motor to lateral rectus (turns eye laterally)
What fibre type(s) does CN VI carry?
Somatic motor
Where does CN VI synapse?
The pons, abducens nucleus
How does CN VI exit the skull?
Via the superior orbital fissure
Outline the route taken by CN VI from its nucleus in the brainstem
CN VI emerges from the pontomedullar junction, passes along the base of the skull, turns up into the cavernous sinus (next to the internal carotid artery) and then through the superior orbital fissure
How would a lesion to CN VI present?
A resting eye in an adducted position, no lateral movement of the eye. Patient will also experience horizontal diplopia