Craab Micro Flashcards
Uncomplicated UTI bacteria
Ecoli, S. Saproohyticus and other enteric microrganisms
E. Coli virulence factors
gm- bacillius faculative anaerobe. P fimbriae, type 1 pillus (fibria), and surface adhesions
surface adhesions which facilitate binding to epithelial cells to initiate colonization. P fimbriae is an adhesion that is a hair like proten structure to interact with a surface receptor on renal epithelial cells
Type 1 pilus: an adhesion which all e. coli strains possess genetically but not all express
Uncomplicated UTI
occurs without underlying abnormality or impairment of urine flow.
Staph Aureus
Gm+ (diplo)cocci faculative anaerobe cat+ coag+
Virulence factors: capsule, adhesins, pathogenicity islands
Strep Viridans
Gm+ cocci Catalase- alpha hemolytic, bacitracin resistant
Enterococcus
Often from genitourinary procedures in older men and obstetric procedures in women. Virulence factors include pili, surface proteins, extracellular enzymes
Strep Pyogenes
Gm+ cocci, catalase+ Beta hemolytic Bacitracin sensitive.
May come from skin or from pharyngitis. M protein causes type II hypersensitivity against heart valves.
Virulence factors: M protien, streptokinase, DNase, Streptolysin O (RBCs) S (WBC)
Exotoxin- Toxic shock syndrome
Myocarditis
Caused by Coxsackie B— CAR receptor
Pericarditis
Pain aleviated by sitting up and leaning forward. Coxsackie A and B, Influenza, Echovirus… summer months fecal oral
Rocky Mountain Spotted Fever
Rickettsia Rickettsii
Triad: Headache, Rash, Tickbite
Rash hands to trunk
OMP A and B
Ciprofloxacin
Flouroquinolone which inhibits DNA Gyrase(top II)
Nitrofurantoin
Antibiotic used to treat UTI, concentrates in the urine, inhibits, DNA, RNA, protein and cell wall synthesis.
Bactrim
Trimethoprim/ Sulfamethoxazole which inhibit the folate pathway in subsequent steps.
