CPP Drugs as per Gavin's email Flashcards
Adrenaline adult IM dose for anaphylaxis or severe allergic reaction
500 microg
Repeated at 5 minute intervals
No max dose
Adrenaline adult IV dose for cardiac arrest
1 mg
Repeated at 3-5 minute intervals
No max dose
Adrenaline adult IM dose for severe life-threatening bronchospasm or silent chest (Pt must only be able to speak in single words and/or have haemodynamic compromise and/or ALOC)
500 microg
Repeated at 5 minute intervals
No maximum dose
Adrenaline Contraindications
Nil
Adrenaline Indications
Cardiac arrest
Anaphylaxis OR severe allergic reaction
Severe life-threatening bronchospasm OR silent chest (patients must only be able to speak in single words AND/OR have haemodynamic compromise AND/OR an ALOC)
Croup (moderate to severe)
Shock unresponsive to adequate fluid resuscitation - CCP only
Bradycardia with poor perfusion - CCP only
Adrenaline Paediatric Newly Born IV Dose for Cardiac Arrest
50 microg
Repeated every 3 - 5 mins
No max dose
Adrenaline Presentation
Ampoule, 1 mg/1 mL (1:1,000) adrenaline
Ampoule, 1 mg/10 mL (1:10,000) adrenaline
Prefilled syringe EpiPen auto-injector, 300 microg adrenaline (yellow)
Prefilled syringe Epi Pen auto-injector, 150 microg adrenaline (green)
Fentanyl Adult Subcut Dose for Significant Pain
QAS clinical consultation and advice line approval required in all situations
Fentanyl Adult ≥70yrs/cachectic or frail NAS Dose for:
Significant Pain
Autonomic Dysreflexia (SBP >160 mmHg)
25-50 microg
Repeated up to 50 microg every 10 mins
Total max dose 100 microg (or MME)
Fentanyl Contraindications
Allergy AND/OR Adverse Drug Reaction
Fentanyl Indications
significant pain
autonomic dysreflexia (with SBP > 160 mmHg)
Sedation - CCP only
Induction for rapid sequence intubation - CCP only
Note: Morphine is the preferred narcotic agent except:
- allergy and or KSAR to morphine
- haemodynamic instability
- known/suspected kidney disease
- when NAS narcotic administration is preferred
- suspected ACS
Fentanyl paediatric NAS dose for significant pain
≥1yr - 1.5 microg/kg
Single max dose 50 microg
Repeated once at 1 microg/kg at 10 mins
Total max dose 100 microg (or MME)
<1yr - QAS clinical consultation and advice line approval required in all situations
Fentanyl Presentation
ampoule, 100 microg/2 mL fentanyl
Glucagon Adult IM Dose - Refractory anaphylaxis with persistent hypotension/shock (unresponsive to 3 x IM adrenaline injections and adequate fluid challenges)
May be administered when paramedics are unable to achieve IV access.
1mg
Single dose only.
Syringe preparation: Reconstitute 1 mg of glucagon with 1 ml of water for injection in a 3 ml syringe to achieve a final concentration of 1 mg/ 1 ml.
Glucagon Adult IM Dose - Symptomatic hypoglycaemia
1mg
Single dose only
Syringe preparation: reconstitute 1 mg glucagon with 1 mL of water for injection in a 3 mL syringe to achieve a final concentration of 1 mg/1 mL
Glucagon Contraindications
Allergy AND/OR adverse drug reaction
Glucagon Indications
Symptomatic hypoglycaemia (with the inability to self-administer oral glucose)
Refractory anaphylaxis with persistent hypotension/shock (unresponsive to 3 x IM adrenaline injections and adequate fluid challenges)
Glucagon Paediatric IM Dose for refractory anaphylaxis with persistent hypotension/shock (unresponsive to 3 x IM adrenaline injections and adequate fluid) for children >25kg
May be administered when paramedics are unable to achieve IV access
1 mg
Single dose only
Syringe Prep: Reconstitute 1 mg of glucagon with 1 mL water for injection in a 3 mL syringe to achieve a final concentration of 1 mg/1 mL.
Glucagon Paediatric IM Dose for Symptomatic hypoglycaemia (with the inability to self-administer oral glucose) for children >25kg
1 mg
Single dose only
Syringe preparation: Reconstitute 1 mg of glucagon with 1 mL of water for injection in a 3 mL syringe to achieve a final concentration of 1 mg/1 mL
Glucagon Presentation
Vials (powder and solvent), 1mg glucagon
Midazolam Adult IM Dose - Acute Behavioural Disturbance (SAT score ≥2) unresponsive to droperidol (max dose) administration
QAS Clinical Consultation and Advice Line approval required in all situations
Midazolam Adult NAS Dose - Generalised Seizure/Focal Seizure
5mg
Repeat every 10 minutes
Total max dose 20mg
Midazolam Contraindications
allergy and/or adverse drug reaction
Midazolam Indications
Generalised seizure/focal seizure (GCS ≤12)
Acute behaviour disturbance (SAT score ≥2) unresponsive to droperidol (max dose) administration
Sedation - CCP only
Midazolam Paediatric IM Dose for Acute Behavioural Disturbance (with a SAT score ≥2), unresponsive to droperidol (max dose) administration
QAS clinical consultation and advice line approval required in all situations
Midazolam Paediatric IM Dose for Generalised/Focal Seizures (GCS ≤12)
200 microg/kg
Single dose not to exceed 5 mg
Repeated at half initial dose every 10 min (max 2.5 mg)
Total max dose 10 mg
Midazolam Presentation
Ampoule, 5mg/1mL, midazolam
Midazolam Timing
Onset
5-15 minutes (IM)
1-3 minutes (IV)
Duration
Variable
- *Half Life**
2. 5 hours
Morphine ≥70yrs/cachectic or frail IM adult dose for:
Significant pain
Autonomic dysreflexia (with SBP >160mmHg)
2.5-5mg
Repeated at up to 5mg every 10 mins
Total max dose 10 mg (or MME)
Morphine adult dose for significant pain via SUBCUT
QAS clinical consultation and advie line approval required in all situations
Morphine Contraindications
Allergy and/or adverse drug reaction
Kidney disease (renal failure)
Morphine Indications
Significant pain
Autonomic dysreflexia (with SBP >160mmHg)
Sedation - CCP Only
Is the preferred narcotic agent except when:
- allergy or KSAR to morphine
- haemodynamic instability
- known/suspected kidney disease
- when NAS narcotic admin is preferred
- suspected ACS
Morphine SUBCUT paediatric dose for significant pain
QAS clinical consultation and advice line approval required in all situations
Morphine paediatric IM dose for:
Significant pain
Autonomic dysreflexia (with SBP >160mmHg)
≥1yr - 100-200 microg/kg
Single max dose 5 mg
Total max dose 200 microg/kg (or MME)
<1yr - QAS clinical consultation and advice line approval required in all situations
Morphine Presentation
Ampoule, 10mg/1 mL morphine sulphate pentahydrate
Sodium Chloride 0.9% adult IV/INF dose - significant burns (TBSA > 20%)
mL/hr to be infused = 15 mL/hr x TBSA (nearest 10%)
if > 100 kg administer additional 200 mL/hr
Re-assess Pt after every 250-500 mL fluid administration
For burns management: use PHIFTEEN B (15-B) formula in adults to identify the hourly parenteral fluid rate goal to be administered for the time of injury
Sodium Chloride 0.9% adult/paediatric IM/IV dose to dissolve and dilute drugs
As authorised on individual DTPs
Sodium Chloride 0.9% adult IV/INF dose:
hypovolaemia
PRN - titrate according to the indication and the pt’s physiological response to treatment
Re-assess Pt after every 250-500 mL fluid administration
In uncontrolled haemorrhage administer the minimum amount of IV/IO fluid required to maintain a radial pulse
Sodium Chloride 0.9% adult/paediatric IV dose as a flush following IV or IO drug administration
PRN
Sodium Chloride 0.9% contraindications
Nil
Sodium Chloride 0.9% Indications
Inadequate tissue perfusion/shock
Hypovolaemia
Significant burns (Total Body Surface Area > 20% for adults or> 10% for paediatrics)
To dissolve and dilute drugs (for the purpose of IM, IV or 10 administration)
As a flush following IV or 10 drug administration
Sodium chloride 0.9% paediatric IV/INF dose for significant burns (TBSA >10%)
QAS clinical consultation and advice line consultation and approval required in all situations
Paediatric pts must be re-assessed after every 10 mL/kg of fluid administration
Sodium chloride 0.9% IV/INF paediatric dose for:
hypovolaemia
QAS clinical consultation and advice line approval required in all situations
10-20mL/kg
May be repeated twice following Pt assessment
Total max dose 60mL/kg
Paediatric pts must be re-assessed after every 10 mL/kg of fluid administration
Sodium Chloride 0.9% presentation
Ampoule, 10 mL sodium chloride 0.9%
Viaflex plastic container, 100 mL sodium chloride 0.9%
Viaflex plasitc container, 500 mL sodium chloride 0.9%
BD PosiFlush 10 mL pre-filled sodium chloride 0.9% syringe
Sodium chloride 0.9% Timing
Onset
Immediate
Duration
Variable
Half-Life
N/A
Glucose 10% Indications
Symptomatic hypoglycaemia (with the inability to self-administer oral glucose)
Unconscious hypoglycaemia - EACP2 only
Glucose 10% Timing
Onset
Rapid
Duration
N/A
Half-Life
N/A
Glucose 10% Adult IV Dose
15g (150mL)
Repeated at 10g (100 mL) boluses every 5 minutes until BGL >4.0mmol/L
Glucose 10% Contraindications
Nil
Glucose 10% Presentation
Viaflex plastic container, 250 mL glucose monohydrate 10%
Glucose 10% Paediatric IV Dose
0.25 g/kg (2.5 mL/kg)
Repeated at 0.1 g/kg (1 mL/kg) boluses every 5 mins until BGL > 4.0 mmol/L
Glucose Gel Indications
Symptomatic hypoglycaemia (with the ability to self-administer oral glucose)
Glucose Gel Timing
Onset
≈ 10 mins
Duration
Variable
Half-Life
N/A
Glucose Gel Adult PO Dose
15g
Repeated once at 15 minutes if BGL ≤ 4mmol/L
Total maximum dose 30g
Glucose Gel Contraindications
Unconsciousness
Patients with difficulty swallowing
Patients < 2 years
Glucose Gel Presentation
Tube, 15g Glucose (Glutose 15)
Glucose Gel Paediatric PO Dose
≥2 yrs - 15 g
Repeated once at 15 mins if BGL ≤4 mmol/L
Total max dose 30 g
Glucose Gel Drug Class
hyperglycaemic
Glucose 10% Drug Class
hyperglycaemic
Fentanyl paediatric IV dose for significant pain
≥1yr - 1 microg/kg
Single max dose 25 microg
Repeated every 5 mins at 0.5 microg/kg (max 25 microg)
Total max dose 2 microg/kg (or MME)
<1yr - QAS clinical consultation and advice line approval required in all situations
Fentanyl paediatric SUBCUT dose for significant pain
QAS clinical consultation and advice line approval required in all situations
Glucagon Adult IV Dose - Refractory anaphylaxis with persistent hypotension/shock (unresponsive to 3 x IM adrenaline injections and adequate fluid challenges)
1 mg
Single dose only.
Syringe preparation: Reconstitute 1 mg of glucagon with 1 ml of water for injection in a 3 ml syringe to achieve a final concentration of 1 mg/1 ml.
Glucagon Paediatric IV Dose for refractory anaphylaxis with persistent hypotension/shock (unresponsive to 3 x IM adrenaline injections and adequate fluid) for children >25kg
1 mg
Single dose only
Syringe Prep: Reconstitute 1 mg of glucagon with 1 mL water for injection in a 3 mL syringe to achieve a final concentration of 1 mg/1 mL.
Morphine ≥70yrs/cachectic or frail IV adult dose for:
Significant pain
Autonomic dysreflexia (with SBP >160mmHg)
2.5mg
Repeated at up to 2.5mg every 5 mins
Total max dose 10 mg (or MME)
Adrenaline adult NEB dose for anaphylaxis or severe allergic reaction
5mg
Single dose only
May be administered for upper airway obstruction that is refractory to 3 X IM adrenaline injections
Fentanyl Adult ≥70yrs/cachectic or frail IM dose for:
Significant Pain
Autonomic Dysreflexia (with SBP >160 mmHg)
25-50 microg
Repeated up to 50 microg every 10 mins
Total max dose 100 microg (or MME)
Fentanyl Adult ≥70yrs/cachectic or frail IV dose for:
significant pain
autonomic dysreflexia (with SBP >160 mmHg)
25 microg
Repeated up to 25 microg every 5 mins
Total max dose 100 microg (or MME)
Morphine paediatric IV dose for:
Significant pain
Autonomic dysreflexia (with SBP >160mmHg)
≥1yr - 100 microg/kg
Single max dose 2.5mg
Repeated at 50 microg/kg (max 2.5mg) every 5 mins
Total max dose 200 microg/kg (or MME)
<1yr - QAS clinical consultation and advice line approval required in all situations
Midazolam Adult IV Dose - Generalised Seizure/Focal Seizure (GCS 12 or less)
If IV already there
5mg
Repeat every 5 minutes
Total max dose 20mg
Fentanyl adult <70yrs IM dose for:
Significant Pain
Autonomic Dysreflexia (with SBP >160 mmHg)
25-100 microg
Repeated up to 50 microg every 10 mins
Total max dose 200 microg (or MME)
Fentanyl adult <70yrs IV dose for:
Significant Pain
Autonomic Dysreflexia (with SBP >160 mmHg)
25-50 microg
Repeated up to 50 microg every 5 mins
Total max dose 200 microg (or MME)