COVID-19, Immune System, Vaccines Flashcards

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1
Q

Innate Immune System

A

Barriers

  • Inflammation
  • Complement
  • Cellular Response
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2
Q

Inflammation

A

Active response to infection. Establishes barrier to spread- triggered by chemicals called cytokines and histamines

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3
Q

Complement

A

Made of proteins that “complement” the adaptive immune system.

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4
Q

Leukocytes

A

different types of White Blood Cells

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5
Q

Cellular Response

A

Mediated by different types of White Blood Cells

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6
Q

phagocytosis

A

cellular eating.

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7
Q

Adaptive Immune System

A

Made of specialized cells that is very specific to one type of antigen

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8
Q

antigen

A

infectious agent

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9
Q

Helper T Cells

A

assist in directing adaptive and innate immune response.

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10
Q

Cytotoxic (Killer) T Cells

A

assist in directing adaptive and innate immune response.

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11
Q

B cells

A

targets infection by producing antibodies

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12
Q

Severe vs mild covid case

A

Innate response is delayed

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13
Q

R0

A

The more contagious, the higher the R0

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14
Q

Live Attenuated

A

virus alive but no longer effective at infecting cells

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15
Q

Pros and cons of Live attenuated vaccine

A

Pro- gives a very robust
Immune response

Cons- poses risk to
People with weakened
Immune system

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16
Q

Killed/Inactive Vaccine

A

Killed

17
Q

Cons of killed/inactive vaccine

A
Cons-
-inactivation can be
   incomplete.
-May not induce as
   strong an immune
   response as live
   vaccine.
18
Q

Component/Subunit

Vaccine

A

Proteins from specific isolated pathogens

19
Q

Cons of component/subunit vaccine

A
Cons-
-May not induce as
   strong an immune
   response as live
   vaccine.
-    Difficult getting pure sample
20
Q

Nucleic Acid-based Vaccine

A

Uses genetic materials from a disease-causing virus