COVID 19

Question 1

Complications of COVID-19 infection

Answer 1

• Respiratory failure/ARDS
• AKI
• Coagulopathies-GI haemorrhage
• Arrythmias
• Acute cardiac injuries- myocarditis, pericarditis
• Acute liver injury
• ‘COVID lung’
• Multi-organ failure
• stroke
• Death

Question 2

COVID-19 Vaccine

Answer 2

• Genetic sequence of SARS-CoV-2 was published on January 11, 2020
• WHO approved 7 Vaccines candidates

a) Two are mRNA vaccines
(BNT-162b2) Pfizer/BioNTech
(mRNA-1273) Moderna

b) Non-Replicating Viral vector vaccine
* (Ad26.COV2.S) Johnson & Johnson
* (AZD1222) Oxford University/AstraZeneca
Covidshield (Oxford/AstraZeneca formulation) Serum institute of India

c) Inactivated
BBIBP-CorV (Vero cells) Sinopharm, Beijing
Sinovac (CoronaVac)

Question 3

What is cytokines storm?

Answer 3

Cytokine storm is an acute systemic inflammatory syndrome characterized by fever and multiple organ dysfunction following certain triggers: sepsis, ARDS,
trauma, immunotherapy, cardiac arrest