Nutrition in Surgery Flashcards

1
Q

What is nutrition and nutrient?

A

Nutrition – The process of utilizing exogenous substances for the production of energy and the synthesis of new tissues.

Nutrient is a substance that is consumed as part of the diet to provide a source of energy, material for growth or their regulation e.g CHO, protein, fat, vitamins & minerals

NUTRITION is an essential component for peri-operative care of surgical patients

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2
Q

Resting energy expenditure (REE)

A

the energy expended by a person at rest in a thermoneutral environment.

REE in newborn 55Kcal/kg/day, in adult 20-30Kcal/kg/day

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3
Q

What is the Difference between REE and BMR?

A

REE and BMR usually differs by less than 10% but REE is higher because it include energy expenditure at mental activity and other expenditure

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4
Q

What is the Basal Requirement?

A

50% - CHO(1g of CHO -4kcal)
35% - Fats(1g of fat -9kcal)
15% - Proteins(1g of protein-4kcal)

These requirements are altered after surgery, trauma or
during infections

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5
Q

What is the daily nuritional requirement?

A

Daily Requirement
Calories:
Adult: 25-35kcal/kg: 2200-2500kcal/day.
Newborn/infants: 90-120kcal/kg/day
Protein 1-1.5g/kg/day
Nitrogen -0.2g/Kg/day
Vitamins:
Vit A – 5000iu wkly
Vit k – 5-10mg wkly
Vit C – 60-80mg/day
Vit B12 – 500mcg wkly
Folic acid 3-6mg/day

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6
Q

What is the daily requirement for Minerals and Trace elements?

A

Zinc – 5mg/day
Cu – 0.5-2.00mg/day
Mn – 70-150mcg/day
Cr – 40mcg/day
Se – 70-150mcg/day

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7
Q

What are the fat solcuble and water soluble vitamins?
Where is Vit. B12 absorbed?
Where is Folic acid absorbed?

A

Fat soluble vitamins –A,D,E,K
Water soluble vitamins –B and C
Vit B12 absorbed in the terminal ileum
Folic acid is absorbed in the duodenum

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8
Q

What are the RISKS ASSOCIATED WITH MALNUTRITION?

A

-impaired wound healing
Impaired immunity
Wound infection
Impaired coagulation
Reduced muscle strength, respiratory function
Post op fatigue

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9
Q

Pathophysiology of Starvation

A

The energy requirement is increased in catabolic states such as surgery, trauma

Major elective abdominal surgeries or trauma by 10-30%, generalized peritonitis 15-50%, sepsis 50-80% and burns 80-200%

If these requirements are not met by exogenous supplement, they will be provided from endogenous alternative ways to the deterrent of the body

In Starvation- 1st 12hrs previous meal utilized and within 24 hrs body glucose store is depleted. after 24hrs fatty acids and amino acids are being broken down (gluconeogenesis)

Obligate use of glucose (the CNS others; rbc, wbc, fibroblast, proximal convulated tubules)

Brain and nervous tissue requires 120g of glucose /day while other obligatory users require 40g of glucose/day

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10
Q

What is malnutrition?

A

There is lack of nutrient in appropriate proportions
Important determinant of surgical outcome

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11
Q

What are causes of malnutrition?

A

Decreased intake
Decreased absorption
Increased losses
Increased utilization

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12
Q

What are the causes of malnutrition via decreased intake?

A
  • Anorexia: liver dx, cancer
  • Neurological disorders
  • Brain surgery
  • Head injury
  • Coma
  • Maxillofacial surgery
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13
Q

What are the causes of malnutrition via decreased absorption?

A
  • Malabsorption syndrome-biliary or pancreatic dx
  • Massive bowel resection
  • Short bowel syndrome
  • GIT fistula (High output
  • GI obstruction (Oesophageal tumour,
  • Oesophageal stricture, Achalasia Cardia,
  • Gastric tumour, Pyloric stenosis)
  • Ulcerative Colitis, Crohn’s disease
  • GIT anomalies in infants
  • Acute radiation enteritis
  • prolonged ileus after major surgery
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14
Q

Causes Hypercatabolic state (increase utilization):

A
  • Major burns
  • Polytrauma patient
  • Sepsis
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15
Q

Nutritional Assessment

A
  • Clinical
  • anthropometry
  • Laboratory evaluation
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16
Q

ASSESSMENT OF NUTRITIONAL STATUS: History

A

Weight loss
History to suggest inadequate intake
Lack of food: 24-hr dietary recall
Eating pattern, dietary restrictions
Anorexia: liver disease, sepsis, cancer
History to suggest increased losses
Persistent vomiting
Chronic diarrhoea
Enterocutaneous fistula e.t.c

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17
Q

How is Nutritional Status assessed?

A

Physical Examination:
- Skin and fluffy hair/hair loss , loose flabby skin, oedema.
- Pallor, muscle wasting (eg loss of thenar muscle)
- peripheral oedema
- peripheral neuropathy
* CVS; displaced apex beat , haemic murmurs
* Abdomen; stomas, fistula, abdominal masses, hepatomegaly
* Rectal examination; perineal fistula, pale stools
* Nervous system; neuropathies

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18
Q

Normal Anthropometric measurement

A
  • weight, Height
  • BMI (19-24.9kg/m2)
  • Skin fold thickness (using skin fold caliper) – M-10mm,F – 13mm
  • Mid upper arm circumference - M ->25cm ,F- >23cm
  • waist –hip ratio –M – <0.94 , F- <0.8
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19
Q

How to measure organ function?

A
  • handgrip dynamometry
  • test of respiratory function
20
Q

Investigations to measure nutriotional status

A
  • Full Blood Count-reduced Hb, reduced total lymphocytes count(<1500/mm3)
  • Mantoux test (anergy)
21
Q

Normal Serum Protein Concentration

A
  • Albumin(g/dl) - < 35g/L (t1/2 -14-21 days),assess nutrition over previous 21 days
  • Transferrin (mg/dl)- t1/2 – 7days
  • Thyroxin-binding pre-albumin-t1/2 -3-5days
  • Retinol-binding protein – assess nutritional status over 12hrs
22
Q

What are the INDICATIONS FOR NUTRITION SUPPORT IN MALNUTRITION?

A
  • Resent unintentional loss of weight more than 15%.
  • Unable to eat for ˃5days (e.g. post abdominal surgery)
  • Significant deficit in hand dynamometry
  • Serum albumin less than 3g/dl.
  • Serum transferrin less than 200mg/dl.
  • Skin anergy.
23
Q

What are Protein Requirements for surgery?

A

Number of non-protein (kcal) given should be a ratio of nitrogen intake 150 - 200kcal:1nitrogen.
1g nitrogen = 6.25g protein.
* Malnourished (not stressed)
1-2g protein/kg/day.
* Postop – no organ failure
1.2-1.5g/kg/day.
* Severely catabolic – no organ failure
1.5-2g/kg/day.

24
Q

What are the various routes of administration

A
  • Enteral
  • Parenteral
25
What is Enteral feeding?
Refers to delivery of nutrients into GIT. Best and preferred route if no contraindication to its use
26
What are the advantages Enteral feeding?
* Less expensive , readily available * Physiologically superior to TPN, portal circulation is not by-passed * Stimulation of intestinal motility * Secretion of IgA * Maintains integrity of GI mucosa(has trophic effects)
27
What are the disadvantages Enteral feeding?
* Aspiration of feeds * GIT motility may change suddenly * Prolonged infusion of nutrients may lead to overgrowth of bacteria * Diarrhoea may be troublesome particularly at the early stages
28
What are the routes for enteral feeding?
Oral intake, feeding tubes, Oral/Sip feeding -natural route
29
What are the types of tube-feeding?
Naso-enteric (gastric, duodenal, jejunal). Oro-enteric (gastric, duodenal, jejunal). Gastrotomy,jejunostomy
30
What are the types of feed given via Enteral Route?
1. Polymeric Blenderised Modular diet 2. Monomeric Partially hydrolysed Elemental diet
31
Types of diet
BLENDERIZED DIET - suitable for patients with normal gut, - Px in whom there is an obstructive lesion in head and neck/oesophagus that interferes with feeding It is made from whole protein (with nitrogen content g/L) and complex starch MODULAR DIET Prepared by dieticians based on targeted total kcal ELEMENTAL DIET pre-digested feeds containing amino acids (and polypeptides), TGs and simple sugars. Thus, absorbed easily SPECIAL PURPOSE (DISEASE SPECIFIC) DIET - Consists of a modular supplementation diet designed to meet the patient’s physiological requirements in the particular disease state such as RENAL, HEPATIC
32
What are Options for Tube feeding schedules?
* Continuous * Intermittent
33
What are some complications of enteric feeding related to feeding regimen?
- intolerance - hyperglycemia - Enteric infection
34
What are some complications of enteric feeding related to feeding tube?
* Malposition * Dislodgement/migration * Aspiration * Peritonitis * Fistula formation * Tube fracture/blockage
35
What are types of enteral feeding options in patients with oesophageal disease, impaired gastric function and recent surgery of the upper GI?
* Gastrostomy * Stamm * Janeway * PEG * Jejunostomy * Witzel * Needle jejunostomy Rectal: (rectal infusion) Not commonly used
36
What is Total Parenteral Nutrition (TPN)?
Is defined as provision of all nutritional requirements by means of intravenous routes and without the use of GI tracts
37
What is Parenteral Nutrition and when is it indicated?
Refers to the provision of part or whole of the patient’s nutritional requirement through the non-enteral route Indicated in patients who require nutritional support but who cannot meet their nutritional needs through enteral route or in whom enteral feeding is contraindicated or not tolerated
38
What is Hyperalimentation?
is the intravenous delivery of nutrients to a malnourished patient or patient in hyper catabolic state in amount as high as 2.5 times his basal requirements in healthy state
39
What are the techniques of infusion?
Peripheral and central vein
40
Peripheral vein
isotonic solution, fats Short period less than 2 wks Change site every 48hrs
41
Central vein
- via IJV or subclavian vein - hyperosmolar/prolong nutrition
42
43
* Infusion protocol/monitoring TPN-team Daily clinical exam Daily blood glucose, urinalysis, electrolytes Weekly LFT, serum Ca, FBC, clotting studies, plasma protein Serum B12, FA, Fe, lactate, trace element every 10-14 days.
44
What are the categories of Complications in parenteral Nutrition?
- technical - metabolic - septic
45
45
46
What are the septic complications of parenteral nutrition?
1. Catheter-related sepsis 2. Infection at skin site. 3. Subclavian vein thrombosis