Course 2: Pathophysiology Flashcards
Pertinent Positives
Specific symptoms that raise the physician’s suspicion for a particular disease.
Pertinent Negatives
Specific symptoms that are not present which cause the physician to doubt certain diagnoses.
Timing
Constant
Intermittent
Waxing and Waning
CAD: etiology
Narrowing of the coronary arteries limits blood supply to the heart muscle causing angina.
Angina
Chest pain specifically due to heart-muscle ischemia.
CAD: catch phrase
Chest pain with physical exertion.
CAD: chief complaint
Chest pain or Chest pressure: worse with exertion, improved by rest or NTG.
CAD: assoc. med.
ASA 324mg PO
NTG 0.4mg SL
CAD: diagnosed by
Cardiac catheterization (not diagnosed in ED)
CAD: scribe alert
- CAD is the single greatest risk factor for MI.
- Stress tests or Cardiac Catheterization assess the severity of CAD.
- A pt has CAD if they have a PMHx pf Angina, MI, CABG, Cardiac stents, or Angioplasty.
- Every pt complaining of CP should always receive Aspirin 324 mg PO, unless it was given PTA or if it is contraindicated due to bleeding or allergy.
MI (stemi, non-stemi): etiology
Acute blockage of the coronary arteries results in ischemia and infarct of the heart muscle.
MI (stemi, non-stemi): catch phrase
Chest pressure with diaphoresis, N/V, and SOB
MI (stemi, non-stemi): risk factors
CAD, HTN, HLD, DM, Smoker, FHx of CA
MI (stemi, non-stemi): CC
Chest pain or chest pressure
MI (stemi, non-stemi): diagnosed by
EKC(stemi) or elevated Troponin (non-stemi)
MI (stemi, non-stemi): assoc. med
ASA
NTG
B-Blocker
Thrombolytic (Heparin)
MI (stemi, non-stemi): scribe alert
- Acute MI pts must receive ASA 324mg as soon as possible.
2. STEMI pts must get to Cath-lab within 90 minutes of arrival. Document ED arrival and depart times.
CHF: etiology
The heart becomes enlarged, inefficient, and congested with excess fluid.
CHF: catch phrase
SOB with pedal edema and orthopnea.
CHF: CC
SOB:
worse when lying flat (orhtopnea)
PND
dyspnea on excertion (DOE)
PND
Paroxysmal nocturnal dyspnea
Orthopnea
SOB when lying flat
CHF: physical exam
Rales in lungs, JVD, in neck, pitting pedal edema.
CHF: assoc. med
diuretics (Lasix, Furosemide) –> Urinate extra fluid.
CHF: Diagnosed by
CXR or elevated BNP
BNP
B-type Natriuretic Peptide
CHF: scribe alert
You can think of CHF as a fluid traffic jam in the heart; fluid gets backed up the neck (JVD) and down the legs (pedal edema).
A Fib: etiology
Electrical abnormalities in the “wiring” of the heart causes the top of the heart (atria) to quiver abnormally.
A Fib: CC
Palpitations (Fast, Pounding, Irregular)
A Fib: risk factors
Paroxysmal A Fib, Chronic A Fib
A Fib: physical exam
Irregularly irregular rhythm, Tachycardia
A Fib: diagnosed by
EKG
A Fib: assoc. med
Coumadin (Warfarin), Digoxin
Coumadin (Warfarin)
Blood thinner, prevents blood clots in atria
Digoxin
Slows down heart rate
A Fib: scribe alert
ED concern is RVR, Theese patients will often be “cardioverted” which means they are put back into a regular rhythm, known as NSR
RVR
Rapid Ventricular Response
Non-cardiac CP: Pericarditis
Inflammation of the sac surrounding the heart causing CP.
Non-cardiac CP: Pleurisy
Inflammation of the sac surrounding the lungs causing pleuritic CP.
Non-cardiac CP: Costochondritis
Irritation of the ribs causing CP worsened by pressing on the sternum.
Non-cardiac CP:
Chest Wall Pain
Irritation of the chest wall causing pain with palpation of the chest.
Non-cardiac CP: Pleural Effusion
Fluid collecting around the lungs causing SOB or CP
MI
Heart attack
Diagnosed by:
EKG (STEMI) or Elevated Troponin (Non- STEMI)
A Fib
Electrical problem
Diagnosed by:
EKG
CHF
Fluid traffic jam
Diagnosed by:
CXR or Elevated BNP
CAD
Major risk factor for MI
Diagnosed by:
Positive cardiac catheterization (not in ED)
Angina
Symptom of CAD
Diagnosed by:
Exertional CP with Hx of CAD
PE: etiology
A blood clot becomes lodged in the pulmonary artery and blocks blood flow to the lungs
PE: catch phrase
Pleuritic chest pain with tachycardia and hypoxia
PE: risk factor
Known DVT, PMHx of DVT or PE, FHx, Recent surgery, Cancer, A Fib, Immobility, Pregnancy, BCP, Smoking
PE: CC
SOB or Pleuritic chest pain (CO worse with deep breaths)
PE: diagnosed by
CTA Chest or VQ scan.
D-dimer
CTA Chest
CT Chest with IV contrast
D-dimer
aids in detecting clots, but cannot diagnose a PE.
PNA: etiology
Infiltrate (bacterial infection) and inflammation inside the lung
PNA: catch phrase
Productive cough with fever
PNA : risk factors
Elderly, bedridden, recent chest injury, recent surgery
PNA: CC
SOB or productive cough
PNA: assoc. med
Rocephin and Zithromax (Abx)
PNA: assoc. Sx
Cough with sputum, fever, CP
PNA: physical exam
Rhonchi
PNA: diagnosed by
CXR
PNA: scribe alert
Core measure: CAP protocol applies to pts with PNA. CAP protocol requires documenting Abx, vital signs, SaO2, mental status and blood cultures
CAP
Community Acquired Pneumonia
PTX
Pneumothorax
PTX: etiology
Collapsed lung due to trauma or a spontaneous small rupture of the lung
PTX: CC
SOB and one-sided chest pain:
Sudden onset
Often trauma pts
PTX: physical exam
Absent breath sounds unilaterally
PTX: diagnosed by
CXR
PTX: scribe alert
Document the percentage of lung collapsed (eg. 20% PTX). These pts will have a chest tube placed to reinflate the lung.
COPD: etiology
Long-term damage to the lung’s alveoli (emphysema) along with inflammation and mucous production (chronic bronchitis)
COPD: risk factors
Smoking
COPD: CC
SOB
COPD: physical exam
Decreases breath sounds, wheezes, rales
COPD: assoc. med
Home O2 (document how much O2 they use at baseline).
COPD: diagnosed by
CXR and hx of smoking
RAD
Reactive Airway Disease
RAD: etiology
Constricting of the airway due to inflammation and muscular contraction of the bronchioles, known as “bronchospasm”.
RAD: CC
SOB/Wheezing:
Improved by nebulizer “breathing treatments” (bronchodilators)
RAD: physical exam
Wheezes (Inspiratory or Expiratory)
RAD: assoc. med
Inhalers, Nebulizers, Corticosteroids
RAD: diagnosed by
Clinically
RAD: scribe alert
The physician will ask the asthma pt:
- Do they have a home nebulizer (machine)?
- Have they been on steroids recently?
- Hx of hospitalization for asthma?
- Hx of intubation (breathing tube)?
- Asthma trigger?
PE
Pleuritic CP with tachycardia and hypoxia
Diagnosed by:
CTA Chest
PTX
Unilateral CP and SOB
Diagnosed by:
CXR
PNA
SOB and productive cough
Diagnosed by:
CXR
COPD
SOB with Hx of smoking
Diagnosed by:
CXR
Asthma
Wheezing with Hx of Asthma
Diagnosed by:
Clinically
Ischemic CVA: etiology
Blockage of the arteries supplying blood to the brain resulting in permanent brain damage
Ischemic CVA: CC
Unilateral focal neurological deficits: One-sided weakness/numbness or changes in speech/vision
Ischemic CVA: risk factors
HTN, HLD, DM, Hx TIA/CVA, smoking, FHx CVA, A Fib
Ischemic CVA: physical exam
Neurological deficits: hemiparesis, unilateral paresthesias, aphasia, visual field deficits
Ischemic CVA: diagnosed by
Clinically, potentially normal CT Head
Ischemic CVA: scribe alert
For any stroke pt ALWAYS document the date and time they were “last known well” (at baseline) as well as the source of this information. This is used to assess eligibility for tPA, a powerful blood thinner that can reverse a CVA.
Document tPA considered and not indicated due to:
1. Onset greater than 3 hours or Unkown/Unreliable time of onset.
2. Symptoms are rapidly improving.
Hemorrhagic CVA
Brain bleed
Hemorrhagic CVA: etiology
Traumatic or spontaneous rupture of blood vessels int he head leads to bleeding in the brain.
Hemorrhagic CVA: CC
Headache: Sudden onset (Thunderclap)
Hemorrhagic CVA: assoc, Sx
Changes in speech, vision, sensation (numbness), or motor strength (weakness), AMS, Seizure, Headache
Hemorrhagic CVA: physical exam
Unilateral neurological deficits
Hemorrhagic CVA: diagnosed by
CT Head or LP
Hemorrhagic CVA: scribe alert
Document “tPA not indicated due to hemorrhage”
TIA: etiology
Vascular changes temporarily deprive a part of the brain of oxygen (Sx usually last less than 1 hour)
TIA: CC
Transient focal neurological deficit:
Changes in Speech, Vision, Strength, or Snesation
TIA: diagnosed by
Clinically
TIA: scribe alert
TIA’s are also known as “Mini Strokes” because Sx usually last
Meningitis: etiology
Inflammation and infection of the meninges; the sac surrounding the brain and spinal cord.
Meningitis: CC
Headache and neck pain
Headache
Cephalgia
Meningitis: assoc. Sx
Fever, neck pain, neck stiffness, AMS
Meningitis: physical exam
Meningismus, nuchal rigidity
Meningitis: diagnosed by
LP
Spinal Cord Injury: etiology
Injury to the spinal cord may create weakness or numbness in the extremities past the sire of the injury
Spinal Cord Injury: CC
Neck pain or Back pain, bilateral extremity weakness
Spinal Cord Injury: physical exam
Midline bony tenderness, deformities, or step-offs, bilateral extremity weakness, numbness, decreased rectal tone.
Spinal Cord Injury: diagnosed by
CT Cervical Spine (Neck)
CT Thoracic Spine (Upper back)
CT Lumbar Spine (Lower Back)
Spinal Cord Injury: scribe alert
remember that during the initial physical exam the spine is often immobilized with a C-collar and backboard; document accordingly.
Sz
Seizure
Sz: etiology
Abnormal electrical activity in the brain leading to abnormal physical manifestations. Often caused by epilepsy, ETOH withdrawals, or febrile seizure in pediatric pts
Sz: CC
Seizure activity, syncope
Sz: assoc. Sx
Injuries (tongue bite), confusion, headache, incontinence (urinary or fecal)
Sz: physical exam
somnolent, confused (Post-Ictal)
Sz: medications
Dilantin, Tegretol Keppra, Depakote, Neurontin
Sz: scribe alert
The physician will ask:
- Has the pt had a similar sz in the past?
- Does the pt have a hx of seizures?
- What was the date of their last seizure?
- What sz medication do they take?
- Have they missed in medication doses?
Bells palsy: etiology
Inflammation or viral infection of the facial nerve causes one-sided weakness of the entire face.
Bells palsy: CC
Facial droop:
Sudden onset
Bells palsy: assoc. Sx
Jaw or ear pain, increased tear flow of one eye
Bells palsy: Pert. Neg
No extremity weakness, no changes in speech or vision.
Bells palsy: physical exam
Unilateral weakness of the upper and lower face.
Bells palsy: Diagnosed by
Clinically
Bells palsy: scribe alert
Bell’s Palsy is the most common cause of facial droop in young pts who do not have CVA risk factors. Remember to document the absence of other FND.
HA: etiology
Various causes including hypertensive headaches (from high blood pressure), recurrent diagnosed migraines, Sinusitis, etc.
HA: CC
headache (gradual or onset)
Pressure, throbbing
HA: Pert. Neg
No fever, no neck stiffness, no numbness/weakness, no changes in speech or vision
HA: scribe alert
Always remember to document if the HA is similar or dissimilar to any prior HA. Never document “Worst headache of life” or “Thunderclap onset” unless specifically instructed by a physician.
AMS: etiology
Multiple causes: most common are hypoglycemia, infection, intoxication, and neurological.
AMS: risk factors
Diabetic, elderly, demented, EtOH use, drug use
AMS: CC
Confusion, decreased responsiveness, unresponsive
AMS: diagnosed by
Case dependent
AMS: scribe alert
AMS is very different than a focal neurological deficit.
AMS is generalized and is typically caused by things that affect the whole brain (drugs, low blood sugar).
Focal neuro deficits are localized weakness/numbness in one specific area, corresponding with damage at one specific site in the brain.
The most common cause of AMS for patients without a hx of dementia is from infection, most often caused by a UTI.
Syncope: etiology
Temporary loss of blood supply to the brain resulting in loss of consciousness. There are a variety of causes; most common are vasovagal and low blood volume (dehydration/hypovolemia). Occasionally syncope occurs due to cardiac/neurologic causes.
Syncope: CC
Passing-out vs. about to pass-out (near-syncope)
Syncope: scribe alert
Document what happened prior, during, and after the syncopal episode, as well as how the patient currently feels.
Vertigo: etiology
Caused by two etiologies: the vertigo may be from a harmless problem of the inner ear (benign positional vertigo), or it may be caused due to damage in a specific center of the brain (possible CVA).
Vertigo: CC
Room-spinning, feeling off balance (disequilibrium):
worsened with head movement
Vertigo: assoc. Sx
N/V, Tinnitus (ringing in ears)
Vertigo: physical exam
Horizontal Nystagmus, + Romberg, + Dix-Hallpike Test
Vertigo: assoc. med
Meclizine (Antivert)
Vertigo: diagnosed by
Clinically
Hemorrhagic CVA
Document:
tPA ineligibility
Ischemic CVA
Document:
tPA eligibility, last known normal
Meningitis
Document:
HA, fever, neck pain
Spinal Cord Injury
Document:
Bilateral extremity weakness