Corticohippocampal System and Memory Flashcards
Define memory and describe the multiple modalities of memory (distinguish between implicit and explicit memory)
Describe the anatomical components of the corticohippocampal system
Describe the basic input/output relationships and functional roles played by the sub-components of the medial temporal lobe system: parahippocampal cortex, perirhinal cortex, entorhinal cortex, and hippocampus proper
Summarize information processing in the hippocampus and distinguish between pattern separation and pattern completion
Explain the role played by the hippocampus in memory consolidation and coactivation, and describe how long-term potentiation strengthens neural pathways
Discuss how and why the hippocampus is reactivated during sleep
Distinguish between major functions of the posterior vs. rostral hippocampus
Evaluate the functions of the posterior cingulate cortex and retrosplenial cortex, and detail how these regions receive inputs from the hippocampus
Relate your knowledge of corticohippocampal circuitry to syndromes of amnesia in patients with neurologic disease
medial temporal lobe amnesia
basal forebrain amnesia
wernicke korsakoff’s
Describe Alzheimer’s disease and compare and contrast with the other most prevalent kinds of major neurocognitive disorder, focusing on the anatomical underpinnings
Contrast basic features of dementia and delirium
Describe dementia with lewy bodies and compare and contrast with the other most prevalent kinds of major neurocognitive disorder, focusing on the anatomical underpinnings
Describe vascular dementia and compare and contrast with the other most prevalent kinds of major neurocognitive disorder, focusing on the anatomical underpinnings
Describe frontotemporal dementia and compare and contrast with the other most prevalent kinds of major neurocognitive disorder, focusing on the anatomical underpinnings
