CORE - Vascular_IR Flashcards
Femoral pseudoaneurysm treatment
direct compression of PSA neck, thrombin injection, or surgery (3 cm or greater); can watch if 1 cm or less
How much thrombin to inject into pseudoaneurysm
500-1000 units (or 0.5 to 1.0 mL); thrombin injection is the preferred method if possible
Contraindications to thrombin injection (for femoral PSA)
local infection, rapid enlargement, distal limb ischemia, large neck, PSA <1 cm; inject APEX of cavity
Vasopressin for GI bleeding
vasoconstrictor, infused directly into SMA or IMA; high re-bleeding rates; may cause NOMI
Complications of vasopressin
arrhythmia, pulmonary edema, hypertension, NOMI; tachyphylaxis develops after 24 hours
Papaverine dose for NOMI
30-60 mg/hr direct arterial infusion
Heparin reversal
protamine; 1 mg IV per 100 units active heparin
Side effects of protamine
sudden drop in BP, bradycardia, flushing
Wire size for 18G and 19G needles
18G needle can fit an 0.038” wire, 19G needle can fit an 0.035” wire; a 19G needle CANNOT fit an 0.038” wire
1 Fr = ___ mm
0.33 mm; also 1 mm = 0.038”
Microwire sizes
0.018” and 0.014”; micropuncture technique refers to a 21G needle and 0.018” diameter wire
Sheaths sizes are designated by inner or outer diameter
inner diameter (add 2 Fr for outer diameter); everything else is by outer diameter
Standard 0.035” wire will fit through what size sheath?
4 Fr or larger
Wire diameters are in ______ and lengths are in ______
diameter in inches, length in cm
Standard wire length (cm)
180 cm (long wire is 260 cm)
Wire tips - floppy, J-tip, hydrophilic, and stiff
floppy = Bentson; J-tip = Rosen; hydrophilic = Glidewire, Roadrunner; stiff = Amplatz, Lunderquist
Size in mm associated with J-tip wires refers to what?
radius of curvature (of the ‘J’); small curves miss small branch vessels, large curves miss large branch vessels
Uses for hydrophilic wires
cross a stenosis, cannulate an indwelling device, enter abscess cavity
Catheter numbers - e.g. 4, 180, 0.035
refers to outer diameter (in Fr), length (in cm), and inner diameter (in inches)
Non-selective (high flow) catheters - pigtail vs. straight
pigtail for injecting medium-to-large vessels; straight for injecting small vessels; both have side and end holes
Selective catheters
end hole only; used for selection and embolization; contrast administered via hand injection only (no pump runs)
Catheter flow rates (by Fr)
3 Fr = 8 ml/s; 4 Fr = 16 ml/s; 5 Fr = 24 ml/s
Angle of catheter for selecting celiac, SMA, or IMA
obtuse angle (>120 degrees); a.k.a. recurve catheter (sidewinder, C2, or sos)
Ideal location for femoral arterial stick
inferomedial margin of femoral head; needle angled 45 degrees cranially for retrograde access and 45 degrees caudally for anterograde access
Location of femoral vein relative to femoral artery just inferior to femoral head
femoral vein is deep to the femoral artery; risk of AVF with low puncture
Treatment for suspected air embolism
left side down and 100% oxygen +/- catheter aspiration if large; insertion of catheter into peel-away sheath is highest risk part of procedure for air embolism
Indications for brachial artery access
upper limb angioplasty or femoral artery is out; risk of stroke if catheter has to cross aortic arch
Which side for brachial artery access?
left brachial if headed “south”, right brachial if headed “north”
Important points of radial artery access (2)
bedrest not required; need to perform Allen test prior to puncture
Contraindication to translumbar aortic puncture
known supraceliac aortic aneurysm
Risk of translumbar aortic puncture
psoas hematoma; used for type 2 endoleak; stick at T12; “self compress” by rolling on back
Anticoagulation during + after angioplasty
should be anticoagulated during procedure to avoid thrombosis from intimal injury (typically with heparin); ASA + plavix for 1-3 months after stenting
Balloon size
10-20% greater than the normal vessel diameter; aorta is 10-15 mm, CIA is 8 mm, EIA is 7 mm, CFA/proximal SFA is 6 mm, distal SFA is 5 mm
Balloon nomenclature
[diameter in mm] x [length in cm], e.g. “10 x 6” = “10 mm in diameter, 6 cm in length”
Balloon-expanding stents
higher radial force, better for more precise deployment; will not rebound if crushed; do not use around joints
Self-expanding stents
more flexible; preferred in tortuous route to lesion or areas prone to external compression
Stent size
1-2 cm longer than stenosis, diameter 1-2 mm wider than unstenosed vessel lumen; 10% oversizing for arterial stents, 20% oversizing for venous stents
Indications for covered stents (no fenestrations)
treatment of pseudoaneurysm, dissection, and TIPS
Primary stenting definition
angioplasty followed by stenting
Particle size for bronchial artery embolization (hemoptysis)
> 325 um; particles <300 um may cause tissue necrosis; NEVER coils
Particle size for UAE
500-700 um
Particle size for GI bleed
300-500 um; particles <300 um may cause bowel infarct
IR procedures with antibiotic prophylaxis
endograft (IV cefazolin 1g), TACE, UAE, TIPS, “pull” gastrostomy (IV cefazolin 1g), PTC/PTBD, cholecystostomy, liver/GU procedures, percutaneous abscess drainage, transrectal percutaneous biopsy, percutaneous vertebroplasty (IV cefazolin 1g)
CO2 contrast
negative contrast agent often used in patients with renal insufficiency or severe contrast allergy, also in TIPS
Swollen left leg
May-Thurner; treatment is thrombolysis + stenting
Splenic artery aneurysm associations
pregnancy, portal HTN, HTN, cirrhosis, liver transplant; pseudoaneuryms classically assoc. with pancreatitis
Increased risk of splenic artery aneurysm rupture
during pregnancy
Indications for splenic artery aneurysm treatment
symptomatic, aneurysm size >2 cm, prior to expected pregnancy
Slow flow rates for AV graft and fistula
<600 cc/min (graft), <500 cc/min (fistula); indication for diagnostic fistulogram; grafts require high flow rates to maintain patency (relative to fistulas)
Dialysis access: arm swelling, chest wall collaterals, and/or breast swelling
central venous stenosis
Dialysis access: pale, discolored, and/or cold hand
dialysis-associated steal syndrome
Dialysis access: high pitched, discontinuous, and/or systolic only bruit
localized stenosis; normal bruit is low-pitched during systole and diastole
Dialysis access: palpable thrill along venous outflow or systolic only thrill
venous stenosis; normall thrill is palpable at arterial anastomosis only during systole and diastole
Dialysis access: water hammer pulse + no thrill (at fistula)
venous outflow stenosis
Dialysis access: diminished pulse + poor thrill (at fistula)
arterial inflow stenosis
Contraindications to fistulography
infected graft/fistula (absolute), <30 days old (relative), stenosis >7 cm long (relative); send latter two back to surgery
Right posterior bile duct drainage
drains segments 6 and 7 - horizontal course
Right anterior bile duct drainage
drains segments 5 and 8 - vertical course
Treatment of iliac atherosclerotic disease
PTA +/- stenting for non-calcified stenosis <3 cm in length (TASC-II); 3-10 cm may be PTA or surgical; stent if >30% residual stenosis or >10 mmHg pressure gradient after angioplasty
Treatment of femoropopliteal atherosclerotic disease
PTA +/- stenting preferred for single lesion <15 cm in length or multiple lesions each <5 cm in length (TASC-II)
Criteria for portal HTN
PV pressure >10 mmHg, PSG >6 mmHg (normal is 3-6 mmHg)
Imaging findings in portal HTN
PV >13-15 mm, splenic vein >12 mm, splenomegaly, ascites, varices, reversal of flow in PV
Indications for TIPS
refractory variceal hemorrhage, refractory ascites, Budd-Chiari; MELD >18 has higher risk of death post-TIPS
Pre-TIPS evaluation (2)
echo to assess for heart failure, CT abdomen to assess for PV patency
Relative contraindications for TIPS
elevated right or left heart pressures, heart failure or valvular insufficiency, rapidly progressive liver failure, severe hepatic encephalopathy, sepsis, unrelieved biliary obstruction; there are no absolute contraindications (per SIR/ACR)
Acute complications post-TIPS
cardiac decompensation, accelerated liver failure, worsening hepatic encephalopathy
Goal PSG post-TIPS
4-12 mmHg; <4 mmHg results in increased risk of encephalopathy; >12 mmHg leads to refractory ascites and variceal bleeding
Findings suggestive of TIPS stenosis
TIPS velocity <90 cm/s or >190 cm/s; interval change +/- 50 cm/s; MPV velocity <30 cm/s; flow away from TIPS; new or increased ascites
Treatment of TIPS stenosis
measure pressure; >12 mmHg => angioplasty
Shunt fraction to reduce dose or contraindicate Y-90
<10% is normal, 10-20% needs a decreased Y-90 dose, >20% is at risk for radiation pneumonitis
Normal PV velocity
16-40 cm/s
Child-Pugh
INR, bilirubin, albumin + ascites and hepatic encephalopathy; classes B and C are higher risk for variceal bleeding
MELD (Model End-stage Liver Disease)
INR, bilirubin, Cr; higher MELD = higher post-TIPS mortality
Indication for BRTO
treatment of gastrorenal shunt (to improve hepatic encephalopathy); diverts blood to portal system
Complications of BRTO
worsening ascites and esophageal varices (basically makes portal HTN worse)
Landing zone criteria (EVAR)
10-15 mm proximal landing zone, non-aneurysmal, angled <60 degrees
EVAR deployment issues
iliac artery angulation >90 degrees, iliac artery diameter <7 mm
Adrenal vein sampling
used to guide treatment of primary hyperaldosteronism; cosyntropin may be administered during sampling
Unilateral adenoma treatment
surgical excision
Bilateral adrenal hyperplasia treatment
oral spironolactone
Most common biliary ductal variants
right posterior to left > trifurcation
PTC, PTBD, biliary stenting, or cholecystostomy prophylaxis
antibiotics (usually levofloxacin for gram negative coverage)
PTC/PTBD approaches
right mid-axillary (fluoro-guided) or left sub-xyphoid (US-guided)
Ideal biliary drain for crossing lesions
internal-external drain; may be converted to internal only
Cholecystostomy approaches
transhepatic (preferred; segments 5/6 => bare area of GB) or transperitoneal (if significant bleeding risk)
How long to leave cholecystostomy in?
2-6 weeks (tract must mature to avoid bile leak); do cholangiogram prior to removal to ensure cystic duct is patent
Management for bile leak
can place biliary drain to divert bile from location of leak
Metallic stent placement
only in patients with life expectancy less than 6 months (median patency of 6-8 months and cannot be removed)
Liver biopsy technique
choose path to ideally biopsy lesion through at least 2 cm of normal liver tissue (don’t biopsy the capsule)
Approach for liver biopsy in patient with severe coagulopathy or massive ascites
transjugular (avoids capsule => less bleeding); assuming ascites cannot be drained for some reason
Rotation of sheath/cannula for transjugular liver biopsy
rotate anteriorly if in right hepatic vein and posteriorly if in middle hepatic vein
Kehr sign
prolonged shoulder pain post-liver biopsy; may represent bleeding (need to check with US)
Contraindications to liver biopsy
uncorrectable coagulopathy, plt <50, RUQ infection
Varicose vein treatment + contraindication
endoluminal heat source (tumescent anesthesia is used); DVT is a contraindication
Spider web appearance (hepatic venogram)
Budd-Chiari
Most common complication of popliteal artery aneurysm
distal thromboembolism
Pre-arterial access management
stop heparin 2 hours before, stop coumadin 5 days before, stop aspirin/plavix 5 days prior; INR >1.5, plt >50, normal PTT
Post-arterial access management
compression for 15 minutes, can resume heparin in 2 hours, groin checks and pulses on nursing orders
Contraindication to arterial closure device
suspected infection at access site
PICC access vessel preference
basilic > brachial > cephalic; use non-dominant arm
Tunneled lines in septic patients
NO; place a temporary line
Relative contraindications for PICC placement
CKD patients, patients on dialysis, patients that may be going on dialysis; “Fistula First Breakthrough Initiative”; these are also CIs for subclavian central line placement
Central line vessel preference
RIJ > LIJ > REJ > LEJ; RIJ is also preferred site for a dialysis catheter
Spiral appearance of wire while attempting to cross a tight stenosis
dissecting wire
Injection rate: aortogram (aortic arch)
20 for 30
Injection rate: abdominal aorta
20 for 20
Injection rate: IVC
20 for 30
Injection rate: mesenteric arteries
5 for 25
Injection rate: renal arteries
5 for 15
Injection rate: distal arteries
3 for 12
Post-embolization syndrome
pain, cramping, fever, and/or nausea/vomiting; starts within 3 days, goes away within 3 days; similar symtpoms may occur post-ablation
Treatment of post-embolization syndrome
NSAIDs, IVFs, +/- opioids
EVAR and TEVAR (acronyms)
EVAR = EndoVascular Aortic Repair (includes abdominal aorta and iliacs); TEVAR = Thoracic-EVAR
Endograft vs. open repair
EVAR has lower 30-day mortality; graft complications and re-interventions are higher with EVAR; long-term aneurysm-related mortality is the same
Indications for EVAR
AAA >5 cm, or growing at >1 cm/year (0.5 cm per 6 months), or symptomatic; may be 5.5 cm
Indications for TEVAR - ascending and descending thoracic aorta
> 5.5 cm and >6.5 cm, respectively (or >5 cm and >6 cm, respectively, for Marfan’s, familial disease, or bicuspid valve); also if growing at >1 cm/year or symptomatic
Crawford type 4 thoracoabdominal aortic aneurysm
aneurysm extending from 12th intercostal space to iliac bifurcation, with involvement of mesenteric and renal arteries
Type 4 and 5 endoleaks
4 = porous graft (most resolve within 48 hours); 5 = endotension
Permanent embolization agents
coils, plugs, particles, sclerosing agents (alcohol or SDS), glue
Temporary embolization agents
gelfoam (2-6 weeks), autologous clot; gelfoam may appear as locules of gas on CT
Strategy for embolizing a specific lesion
coil distal to lesion, then proximal to lesion (prevents collateral flow); cannot use for “end” arteries
Coils vs. particles
coils can be placed precisely (no distal embolization); particles flow distally to occlude small capillaries
Vessel to embolize: uterine fibroids
bilateral uterine arteries; particles
Vessel to embolize: varicocele
gonadal vein (a.k.a. testicular or spermatic vein)
Vessel to embolize: diffuse splenic trauma
proximal splenic artery (before short gastrics); Amplatz plug; short gastrics maintain some splenic perfusion
Vessel to embolize: hemoptysis
bronchial artery; particles (NOT coils)
Signs of irreversible limb ischemia
complete muscle paralysis, complete sensory loss, no venous flow on Doppler (loss of arterial flow may still be salvageable)
Cause of acute limb ischemia
thrombotic and/or embolic events; most common source is a left atrial thrombus (Afib) => echo to identify source
5 P’s of acute limb ischemia
pain, pallor, pulseness, paresthesias, poikilothermia (cold); emergency
Endovascular treatment of acute thromboembolism (technique)
cross lesion with hydrophilic wire; infuse tPA via multi-sidehole catheter (0.5 mg/hr for 48-72 hours)
When to slow and stop intra-arterial tPA
slow if fibrinogen decreases to <150 mg/dL; stop if fibrinogen <100 mg/dL; patient should be monitor in ICU during infusion
ABI: normal
1.0-1.4; >1.4 is non-compressible due to calcification; ABI = ankle SBP / brachial SBP
ABI: borderline
0.9-0.99
ABI: abnormal
<0.9; claudication at 0.5-0.9, rest pain at 0.3
Foot ulcers: medial ankle, dorsal foot, plantar foot
medial ankle = venous stasis; dorsal foot = infection/ischemic; plantar foot = neuropathic (diabetes)
Risk factors for peripheral vascular disease (chronic)
smoking, diabetes, HTN, hyperlipidemia, no exercise, family history; claudication => rest pain => tissue loss
Classification systems for peripheral vascular disease
Rutherford and Fontaine
Lower extremity arterial access: when to access via contralateral CFA
ipsilateral CFA lesion or EXTREMELY obese; iliac, SFA, and fem-pop graft lesions are all accessed via ipsilateral CFA
Lower extremity arterial access: access for fem-fem bypass
direct stick > inflow CFA
tPA patient with new confusion - NEXT STEP
stop tPA + head CT
tPA patient with hypotension and tachycardia - NEXT STEP
stop tPA + check site +/- CT abdomen/pelvis (patient is bleeding out)
Post-thrombotic syndrome
pain and venous ulcers after DVT; prevent with catheter-directed thrombolysis of iliofemoral DVTs
Indications for IVC filter placement
DVT with contraindication to AC, recurrent PE while on AC, need to discontinue AC due to complications, high risk of developing DVT/PE with contraindication to AC
Most common complication of IVC filter placement
access site thrombosis > IVC thrombosis
Indication for bird’s nest IVC filter
28-40 mm IVC diameter; if >40 mm, separate IVC filters can be placed in the common iliacs
IVC filter retrieval
clot in filter needs to be lysed prior to removal; may retrieve while the patient is anticoagulated; cavogram should be performed after removal (assess for tear)
Risk of suprarenal IVC filter
renal vein thrombosis
Indications for suprarenal IVC filter placement
prengnacy (avoid compression), clot in renal or gonadal veins, duplicated IVC (may also be bilateral iliac filters)
IVC filter placement with circumaortic left renal vein
below lowest renal vein (usually circumaortic vein); retroaortic renal vein may insert low on the IVC
Nitroglycerin - spasm vs. stenosis
spasm will improve with nitroglycerin, while stenosis will not