CORE - Peds Flashcards
Telephone receiver femurs
thanatophoric dysplasia
Cloverleaf skull
thanatophoric dysplasia, severe Apert syndrome, severe Crouzon syndrome
Platyspondyly
thanatophoric dysplasia
Anterior beaking of mid vertebral body
Morquio’s
Anterior beaking of inferior vertebral body
Hurler’s
Banana sign
Chiari II - appearance of the cerebellum
Lemon sign
Chiari II - appearance of the skull shape
Luckenschadel skull
associated with Chiari II - dysplasia of the skull with multiple rounded lytic defects; affects inner table
Hair-on-end skull
thalassemia, sickle cell disease
Most common cause of cyanosis in newborn
Transposition of the great arteries
Wimberger sign
Congenital syphilis
Celery stalk metaphyses
Congenital rubella
Floating tooth in the mandible
Eosinophilic granuloma
Wide angled mandible and dwarfism
pycnodysostosis
Osteonecrosis of the mandible (peds)
OI on bisphosphonates
Wimberger ring sign
Circular calcification surrounding the osteoporotic epiphyseal center of ossificatoin in scurvy - may result from bleeding
Subperiosteal hemorrhage
Scurvy
Gingival bleeding
Scurvy
Intralobar sequestration, most common location
LLL
Congenital lobar emphysema, most common location
LUL
Bronchial atresia, most common location
LUL
Elevated endothelial growth factor (EGF)
Hemangioendothelioma; follows peripheral nodular discontinuous enhancement pattern
Elevated AFP DDx
Hepatoblastoma, HCC, gastroschisis, yolk sac tumor (testes), pancreatoblastoma, anencephaly
Subglottic hemangioma
assoc. with PHACES syndrome (P = Dandy-Walker), cutaneous hemangiomas; most commonly left-sided
Cutaneous hemangioma
assoc. with PHACES syndrome (P = Dandy-Walker)
Ropy opacities
Meconium aspiration
Pneumothorax (neonate)
Meconium aspiration
Fluid in the fissures (neonate)
TTN
Granular opacities, premature, low lung volumes
RDS
Granular opacities, normal/increased lung volumes
PNA
Granular opacities, low lung volumes, pleural effusion
B-hemolytic strep PNA
Band-like opacites (neonate)
CLD/BPD
Non-bilious vomiting (3 weeks to 3 months) + NEXT STEP
Hypertrophic pyloric stenosis; next step is ultrasound
Paradoxical aciduria
Hypertrophic pyloric stenosis
Thickness and length hypertrophic pyloric stenosis
4 mm and 14 mm
Posterior mediastinal mass <2 y/o
Neuroblastoma
Absent or hypoplastic GB
Biliary atresia
Triangle cord sign
Biliary atresia - triangular or tubular echogenic cord of fibrous tissue seen in the porta hepatis at ultrasonography
Asplenia
Congenital heart disease
Splenic infarct
SCD
Gallstones
SCD
Fishmouth or H-shaped vertebrae
SCD, Gaucher’s
Hand or foot pain/swelling (infant)
Hand-foot syndrome (dactylitis in SCD)
Short microcolon
Mid to distal colonic atresia, Hirschsprung’s (dependent on length of involvement)
Long microcolon
Meconium ileus, ileal/proximal colonic atresia, total colonic Hirschsprung’s
Calcified abdominal mass in newborn
Meconium peritonitis
Meconium ileus equivalent
DIOS
Abrupt caliber change of aorta below celiac origin
Hepatic hemangioendothelioma (shunt)
Cystic mass in liver of newborn
Mesenchymal hamartoma
Unilateral renal agenesis
Unicornuate uterus (females); absent vas deferens/epididymis, seminal vesicle cysts (males)
Neonatal renal vein thrombosis
Maternal diabetes
Neonatal renal artery thrombosis
Misplaced umbilical artery catheter (should be at T8-10 or L3-5)
Hydronephrosis on fetal MRI
Posterior urethral valve
Urachal anomaly assoc. malignancy
Adenocarcinoma
Solid renal tumor in <3 month old
Mesoblastic nephroma
Solid renal tumor of childhood
Wilms
Midline pelvic mass in female
Hydrometrocolpos
Blue dot sign
Torsion of testicular appendage (>5 mm)
Extratesticular scrotal mass
Rhabdomyosarcoma
Narrowing of interpedicular distance
Achondroplasia
Tombstone iliacs
Achondroplasia
Champagne glass pelvic inlet
Achondroplasia
Trident hands
Achondroplasia; short fingers with a separation between the 3rd and 4th digits
Posterior vertebral scalloping
Achondroplasia, NF1, Marfan’s, Ehlers-Danlos, intraspinal mass, mucopolysaccharidoses
Idiopathic scrotal edema
Henoch-Schonlein purpura
Acute scrotal pain age 7-14
Torsion of testicular appendage (most common), testicular torsion, epididymitis
Physiologic periostitis of the newborn
1-4 months; femur before tibia, always diaphyseal
Acetabular angle should be
<30
Alpha angle should be
> 60
Klein’s line
along lateral femoral neck; for SCFE
Hilgenreiner line
drawn through triradiate cartilage; ‘H’ for horizontal
Perkins line
drawn through lateral acetabulum; ‘P’ for perpendicular to Hilgenreiner line
Most common symptomatic vascular ring
Double aortic arch
Neonatal infection with frontal lobe atrophy
HIV
Dolicocephaly
Sagittal suture fusion
Brachycephaly
Bilateral coronal or lambdoid suture fusion
Plagiocephaly
Unilateral coronal or lambdoid suture fusion
Trigonocephaly
Metopic suture fusion
Turricephaly
Sagittal, coronal, and lambdoid suture fusion
Right-sided heterotaxia
bilateral major/minor fissures, asplenia, more cardiac malformations, aorta on the right side of the spine
Left-sided heterotaxia
bilateral single fissures, polysplenia, fewer cardiac malformations, azygous continuation
Congenital CMV (CNS)
periventricular calcifications, pachygyria-lissencephaly, hydrocephalus
Congenital toxoplasmosis (CNS)
basal ganglia calcifications, hydrocephalus
Congenital HSV (CNS)
hermorrhagic infarction => bad encephalomalacia
Congenital HIV (CNS)
frontal lobe atrophy
Caffey disease
<6 m/o, self-limited; periosteal reaction, soft-tissue swelling, irritability; affects mandible, ulna, and clavicle; hot on bone scan
Wormian bones DDx
Pycnodysostosis, OI, Rickets, Kinky hair syndrome, Cleidocranial dysostosis, Hajdu-Cheney, Syndrome of Downs
Differential for high output cardiac failure in pediatric patient
Hepatic hemagnioendothelioma, vein of Galen malformation, sacrococcygeal teratoma
Grade 1 VUR
reflux into ureter only
Grade 2 VUR
reflux into renal pelvis, no dilation
Grade 3 VUR
mild dilation of ureter and pelvicalyceal system
Grade 4 VUR
tortuous ureter with moderate dilation, pelvicalyceal blunting with preserved papillary impressions
Grade 5 VUR
tortuous ureter with severe dilation of the ureter and pelvicalyceal system, loss of fornices and papillary impressions
VUR treatment
grades 1-3 with antibiotics only, grades 4-5 with antibiotics +/- reimplantation
Rhizomelic
Proximal limb shortening
Mesomelic
Mid limb shortening
Acromelic
Distal limb shortening
Most common congenital heart disease
Bicuspid aortic valve or VSD (depends on wording)
Aortic coarctation associations
assoc. with Turners, bicuspid aortic valve
Extra-cardiac shunts
hepatic hemangioendothelioma, vein of galen malformation, sacrococcygeal teratoma
type 1 TAPVR
Supracardiac (50%) - snowman sign
type 2 TAPVR
Cardiac (30%)
type 3 TAPVR
Infracardiac (20%) - veins drain below the diaphragm (hepatic or IVC); often causes pulmonary edema in newborns
Double aortic arch
right arch is classically higher and larger compared to the left arch
Risk factors for germinal matrix hemorrhage
prematurity, multiple gestations, birth trauma, prolonged labor
Pectus excavatum
Haller index = transverse diameter / AP diameter; >3.25 => surgical correction
Causes of pulmonary hypoplasia
CDH, Potter sequence, decreased vascular supply
CCAM types
1 = cystic; 2 = mixed; 3 = solid; treatment is resection
Congenital diaphragmatic hernia
Bochdalek hernia most commonly; almost all are malrotated; when right-sided assoc. with GBS pneumonia
Bronchiolitis obliterans
air trapping, mosaic attenuation, bronchiectasis, bronchial wall thickening
Pleuropulmonary blastoma
1-2 y/o, usually right-sided, mixed cystic and solid, no calcifications or rib invasion
UVC position
cavoatrial junction
UAC position
high position (T8-10) or low position (L3-5)
SMA on ultrasound
echogenic halo of fat
Malrotation associations
heterotaxy, omphalocele, CDH
Small left colon syndrome associations
pre-term delivery, diabetic mothers, mag sulfate
High obstruction in a neonate - NEXT STEP
Upper GI series to exclude midgut volvulus (emergency)
Low obstruction in a neonate - NEXT STEP
Contrast enema to exclude surgical causes (Hirschsprung’s, colonic/ileal atresia) from non-surgical causes (small left colon syndrome, meconium ileus)
Imperforate anus associations
VACTERL, caudal regression syndrome; may need to assess for GU fistula
Contraindications to air/contrast enema for intussusception
peritoneal signs or free air (should go straight to surgery)
Increased risk of NEC
pre-term delivery, low birth weight, congenital heart disease, Hirschsprung’s, hyperosmolar feeds
Omphalocele associations
trisomy 18, allantoic cysts, cardiac anomalies, Beckwith-Wiedemann, caudal regression syndrome, malrotation
Dorsal pancreatic agenesis
increased risk of diabetes; associated with polysplenia
Biliary atresia associations
polysplenia, trisomy 18, Alagille syndrome
Retrocaval ureter
fishhook or J-shaped
Allantois
becomes urachus (which is between the bladder and umbilicus)
Omphalomesenteric duct
a.k.a. vitelline duct; fetal connection between umbilical cord and midgut; persistence is a Meckel’s
Bladder exstrophy associated malignancy
increased risk of adenocarcinoma
Wilms tumor associations
Beckwith-Wiedemann, WAGR, horseshoe kidney, trisomy 18, Denys-Drash
Neuroblastoma - stage 4S
<1 y/o, confined to skin, liver, and bone marrow; excellent prognosis
Hydrometrocolpos association
didelphyc uterus
Hydrocele with septations
hematocele or pyocele
Isolated orchitis
mumps
Paratesticular mass
rhabdomyosarcoma or hematoma (with h/o trauma)
Pediatric elbow fracture prevalence
supracondylar fracture > lateral condylar fracture > medial epicondylar fracture/avulsion
Little league elbow
medial epicondylar fracture/avulsion
Neonatal periosteal reaction
physiologic, prostaglandins, rubella, syphilis, neuroblastoma mets, Caffey disease
Fracture(s) with hyperplastic callus
osteogenesis imperfecta
“Bone-in-bone” appearance of carpals or vertebral bodies
osteopetrosis
Small, skinny vertebral bodies
Klippel-Feil syndrome; with cervical fusion anomalies
Hindfoot valgus
flat foot, a.k.a. pes planus; talocalcaneal angle >40 degrees
Hindfoot varus
club foot, a.k.a. talipes equino varus; talocalcaneal angle <25 degrees
Increased risk of DDH
girls, breech birth, oligohydramnios, first born, family history
Rickets in a newborn
hypophosphatasia (deficient alkaline phosphatase)
Stippled epiphyses DDx
chondrodysplasia punctata, maternal coumadin use, hypothyroidism, Fairbank disease
Tethered cord associations
caudal regression syndrome, VACTERL, most open or closed spinal dysraphisms
Absent thumb and radius DDx
VACTERL, Holt-Oram, Fanconi anemia
Surfactant replacement therapy
increased risk of pulmonary hemorrhage and PDA; can mimic PIE
Recurrent pneumonia in same location
intralobar sequestration
Absent vas deferens
unilateral renal agenesis or cystic fibrosis
Spinnaker sail sign
pneumomediastinum
Mediastinal mass with calcification DDx (peds)
neuroblastoma, treated lymphoma, teratoma
Increased risk of extra-gonadal germ cell tumors
Klinefelter’s syndrome (specifically NSGCT)
Increased risk of male breast cancer
Klinefelter’s syndrome
Most common type of TEF
N-type (blind-ending esophagus with TE fistula to distal esophagus)
Criteria for VACTERL diagnosis
3 or more anomalies
Duodenal atresia associations
prematurity, Down syndrome, polyhydramnios
“Double bubble” with distal bowel gas
midgut volvulus, duodenal stenosis, duodenal web, annular pancreas
Ladds bands
cause obstruction in the setting of malrotation
Organoaxial gastric volvulus
old ladies with paraesophageal hernias
Mesenteroaxial gastric volvulus
peds, may cause ischemia and/or obstruction
Annular pancreas (peds)
duodenal obstruction
Annular pancreas (adults)
pancreatitis
Treatment for meconium ileus and small left colon syndrome
enema
Cutoff for small vs. large bowel intussusception
2.5 cm
Lead points for intussusception
lymph nodes, HSP, Meckel’s, enteric duplication cysts
Most common cause of pancreatitis (peds)
trauma
Kasabach-Merritt syndrome
assoc. with hemangioendothelioma
Hepatoblastoma associations
Wilms, Beckwith-Wiedemann, hemi-hypertrophy
Caroli’s disease associations
polycystic kidney disease (AR > AD), medullary sponge kidney
Diffuse liver metastases (infant or toddler)
neuroblastoma or Wilms; if <6 m/o => neuroblastoma
High imperforate anus fistula
vesicorectal (males) or vaginorectal (females)
Low imperforate anus fistula
perineal fistula
“Pancake adrenal gland”
congenitally absent kidney
Most common congenital GU anomaly
UPJ obstruction
Whitaker test
to differentiate UPJ from an extra-renal pelvis; urodynamics + antegrade pyelogram
No urine in bladder in utero
bilateral renal agenesis, ARPKD
Causes of primary megaureter
idiopathic, distal adynamic segment, reflux at UVJ
Obstructive causes of hydronephrosis in male neonates
UPJ obstruction, PUV, ureteral ectopia (obstructs)
Non-obstructive causes of hydronephrosis in male neonates
VUR, primary megaureter, prune belly syndrome
Most common complication of a urachal remnant
infection
Screening for Wilms in nephroblastomatosis
q3 months until age 7
Renal scintigraphy with no excretory function (neonate)
renal agenesis, MCDK
Beckwith-Wiedemann (3 associations)
Wilms, hepatoblastoma, omphalocele
WAGR syndrome
Wilms, Aniridia, Genital anomalies, Retardation of growth
Wilms-like tumor + bone mets
clear cell sarcoma; regular Wilms most commonly mets to lungs
“Bunch of grapes” in the pelvis
Botryoid rhabdomyosarcoma; this variant occurs in the bladder and vagina most commonly
Neuroblastoma associations
NF-1, Hirschsprung’s, DiGeorge syndrome, Beckwith-Wiedemann
Scrotal hemorrhage (neonate)
assoc. with adrenal hemorrhage
“Cerebriform” adrenal gland
adrenal hyperplasia
Ovarian torsion
swollen ovary, peripheral follicles, no flow
Most common cause of painless scrotal swelling
hydrocele
Large or coarse testicular calfications
NSGCT
Most common testicular tumors in 1st decade
yolk sac tumor, teratoma
Sertoli cell tumor associations
Peutz-Jeghers, Klinefelter’s
5+ y/o elbow
“Where is the medial epicondylar ossification center?”
Lucent skull lesions (peds)
EG, neuroblastoma mets, Luckenshadel skull (Chiari II)
Fibula longer than tibia
osteogenesis imperfecta
Wormian bones, acroosteolysis, osteosclerosis
pycnodysostosis
Sprengel deformity (high-riding scapula)
Klippel-Feil syndrome; assoc. with an omovertebral bone
Caudal regression syndrome associations
VACTERL, Currarino triad
Currarino triad
anorectal malformation, sacrococcygeal osseous defect, presacral mass (meningocele, teratoma, hamartoma)
Presacral mass DDx
sacrococcygeal teratoma, meningocele, rectal duplication cyst
Absent radius DDx
VACTERL, Holt-Oram, Fanconi anemia, thrombocytopenia absent radius (TAR)
Medial subluxation of the navicular
club foot (talipes equinovarus)
Hip pain with with widened joint space - NEXT STEP
septic arthritis must be excluded
Kocher criteria
fever, inability to bear weight, elevated ESR/CRP, WBC >12; 3 or more is positive for septic arthritis
Duodenal hematoma (infant)
NAT
Pancreatitis (infant)
NAT
Piriform aperture stenosis associations + NEXT STEP
central mega-incisor, agenesis of the corpus callosum, holoprosencephaly; next step is image the brain
Dimple screening
high dimples (above gluteal crease) are screened; low dimples are not
Excessive expiratory airway collapse (>50%)
tracheobronchomalacia
Massive perinatal pericardial effusion
pericardial teratoma
Soap bubble luciences in RLQ (x-ray)
meconium ileus
Simple renal cyst(s) associations
tuberous sclerosis, VHL
Abnormal anterior humeral line
supracondylar fracture
Abnormal radiocapitellar line
elbow dislocation
Salter-Harris type of an avulsion injury
Salter-Harris type 1
Skeletal survey
frontal view of all long bones, rib views with obliques, skull, pelvis, hands/feet, entire spine
J-shaped sella
mucopolysaccharidoses, achondroplasia, NF1
Madelung deformity associations
prior trauma, Turner syndrome, Hurler’s, achondroplasia, multiple hereditary exostoses
Oncogenic rickets
seen with hemangiopericytoma or non-ossifying fibroma
Alagille syndrome
intrahepatic biliary atresia, peripheral pulmonary artery stenosis
Salter-Harris type for a lateral condylar fracture
Salter-Harris type 4
Cyst with trilaminar wall
enteric duplication cyst
Hemolytic uremic syndrome
renal failure, hemolytic anemia, thrombocytopenia; enlarged echogenic kidneys; due to E. coli most commonly
Echogenic chest mass (neonate)
CLE, CDH, sequestration, CCAM
Congenital venolobar syndrome
a.k.a. scimitar syndrome (RLL PAPVR + pulmonary hypoplasia)
Work-up for pediatric bone tumor (any)
MRI of affected limb, CT chest, whole body surveillance (skeletal survey, bone scan, or MIBG)
Small thorax with a distended abdomen
consider renal issues (Potter sequence)
Age for ganglioneuroma
> 10 y/o
Echogenic pulvinar
seen in DDH; femoral heads will be displaced
Pediatric ovarian neoplasms
GCTs are most common regardless of age (also most common amongst malignant ovarian tumors)
Infant with UTI by urinalysis - NEXT STEP
renal ultrasound to evaluate for pyelo or structural anomalies
Indication for VCUG in an infant
recurrent UTI or abnormal renal ultrasound
% SCFE is bilateral
25%; Tx for SCFE is surgical pinning
Complications of SCFE
FAI, chondrolysis, avascular necrosis
Renal mass with a subcapsular fluid collection
rhabdoid tumor of the kidney
Anterior mediastinal mass DDx (peds)
lymphoma, leukemia, GCT (teratoma, seminoma, NSGCT), thymic rebound, normal thymus
Most common extra-ocular orbital malignancy (peds)
rhabdomyosarcoma
Lytic lesion of bony pelvis DDx (peds)
Ewing’s, osteosarcoma, EG, neuroblastoma met, lymphoma/leukemia, osteomyelitis
Diffusely sclerotic bones DDx
osteopetrosis, pycnodysostosis, hypervitaminosis A, renal osteodystrophy, fluorosis
Age when DDH screening shifts from US to x-ray
6 months (when femoral heads ossify)
Situs solitus
normal position of chest and abdominal organs
Copper-beaten skull
hydrocephalus
ARPKD types
infantile = worse renal disease, less hepatic fibrosis; juvenile = less renal disease, more hepatic fibrosis
Short femurs
skeletal dysplasia (especially achondroplasia)
Criteria for BPD
abnormal CXR + persistent need for oxygen at 36 post-conceptual weeks or at 28 days of life
Most common benign liver tumor (peds)
infantile hepatic hemangioma
Bony findings in achondroplasia
bullet-shaped VBs, posterior VB scalloping, decreasing interpedicular distance, horizontal acetabular roofs, tombstone iliac bones, exaggerated lumbar lordosis
Diabetic mother associations
TGA, TTN, small left colon, renal vein thrombosis, caudal regression syndrome
Intussusception reduction procedure
surgeon present, large bore needle available, large enema tip, up to 120 mmHg; up to 3 attempts up to 3 minutes each
High vs. low imperforate anus landmark
puborectalis sling
Physiologic jaundice of the newborn
unconjugated hyperbilirubinemia; note that conjugated hyperbilirubinemia is never normal