COPD Flashcards
1
Q
what is COPD
A
abnormal chronic inflammatory response of airways to noxious particles or gases
2
Q
past definitions of COPD
A
- chronic bronchitis
- emphysema
3
Q
cardinal symptoms of COPD
A
- dyspnea
- difficulty breathing
- SOB
- limitations in activity
4
Q
COPD significance
A
- 9.4% Canadians >35
- comparable gender prevalence
- higher among first nations
5
Q
risk factors of COPD
A
- smoking
- occupational chemicals or dust
- air pollution
- infection
- aging
6
Q
tobacco smoke and sympathetic nervous system
A
- increases HR
- peripheral vasoconstriction
- increases BP
- increases cardiac workload
7
Q
tobacco smoke and the respiratory tract
A
- increased mucus production
- hyperplasia of goblet cells
- decreased ciliary activity
8
Q
tobacco smoke and carbon monoxide
A
- decreased O2 carrying capacity
- increase HR
- impair psychomotor performance and judgement
9
Q
passive smoking (environmental tobacco smoke or secondhand smoke)
A
- decrease pulmonary function
- increase risk of lung cancer
- increase rate of mortality fro ischemic heart disease
10
Q
respiratory tract infections
A
- recurring infections impair normal defence mechanisms
- reduce lung function
- pathological destruction of lung tissue
11
Q
alpha - antitrypsin (AAT) deficiency
A
- genetic risk factor for COPD
- occurs in 1 and 5000
12
Q
aging and emphysema
A
- loss of elastic recoil in lungs
- lungs are rounded and smaller
- number of functional alveoli decreases
- peripheral airways lose support
13
Q
COPD defining features
A
- airflow limitations during forced exhalation due to loss of elastic recoil
- airflow obstruction due to mucus hyper secretion, mucosal edema and bronchospasm
14
Q
process of respiratory inflammation
A
- inhalation of noxious particles
- mediators released cause damage to lung tissue
- airways inflamed
- parenchyma destroyed
15
Q
COPD and supporting structures
A
- air goes in easy but remains in lungs
- bronchioles tend to collapse
- causes barrel-chest look
16
Q
lung changes in COPD
A
- bronchioles lose their shape and become clogged with mucus
- alveoli walls are destroyed forming fewer larger ones