control of water and electrolytes Flashcards
water is gained by which 2 methods?
- ingestion
- formed in metabolism
water is lost by which 2 methods?
- excretion
- evaporation
how much water does the average person gain and lose per day?
2400ml
which hormone is the main control for water?
ADH
how are sodium levels controlled?
- renin-angiotensin-aldosterone system
- atrial natriuretic hormone
what does the renin-angiotensin-aldosterone system do?
- promote reabsorption of sodium and water in distal convoluted tubule
what is angiotensin?
potent vasoconstrictor
what does atrial natriuretic hormone do?
increase excretion of sodium and water
which hormone has the opposite effect of atrial natriuretic hormone?
aldosterone
which hormone regulates potassium levels?
aldosterone
hypo secretion of ADH causes what condition?
diabetes insipidus
hyper secretion of ADH results in what?
water retention
what effect does increased ECF potassium have on nerve function?
depolarisation causing APs and prolonged refractory period
how do potassium salts in toothpastes work to desensitises teeth?
- potassium ions diffuse along dentinal tubules raising potassium concentration at the inner end of the tubule
- this depolarises the nerve, sodium channels are inactivated, and prolonged refractory period is sustained