control of pain + anxiety Flashcards

1
Q

what is allodynia

A

pain from non-painful stimuli

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2
Q

what is hyperalgesia

A

exaggerated response to noxious stimuli

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3
Q

2 effects of paracetamol

A

antipyretic

analgesia

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4
Q

risk of paracetamol

A

liver toxicity in compromised pts

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5
Q

risks of NSIADs

A

gastric ulceration

bleeding

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6
Q

pts when NSAIDs are contraindicated

A
elderly
previous hypersensitivity 
pregnancy/breastfeeding
history of gastrointestinal bleed/ulcer
renal impairment 
hepatic impairment  
coagulation defects 
cardiac impairment 
asthmatics - increased risk of hypersensitivity
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7
Q

drug prescribed alongside NSAIDs to offer gastrointestinal protection

A

proton pump inhibitors - ols

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8
Q

drugs developed to have same affects as NSAIDs without side effects

A

selective COX-2 inhibitors

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9
Q

why do NSAIDs cause side effects

A

not selective - COX1 also inhibited

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10
Q

side effects of opioids

A

nausea/vomiting

respiratory depression

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11
Q

example of a weak opioid

A

codeine or dihydrocodeine

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12
Q

example of a strong opioid

A

morphine

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13
Q

why may it be important to give systemic analgesia before LA worn off?

A

reduce risk of sensitisation

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14
Q

where are amino-ester LAs metabolised?

A

in plasma by pseudocholinesterase

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15
Q

where are amino-amide LAs metabolised?

A

in liver

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16
Q

3 general complications of LA

A

psychogenic
toxic
allergy

17
Q

allergy most likely with what type of LA?

A

esters

18
Q

3 local complications of LA

A

soft tissue trauma
nerve trauma - paraesthesisa
intravascular injection - haematoma, systemic effects

19
Q

complications of IDB

A

injection in medial pterygoid - trismus
deep injection in parotid gland - facial nerve = facial muscle paralysis temporary
electric shock = needle touches IAN

20
Q

medical indications for conscious sedation

A

mild angina, hypertension, asthma
spasticity, MS, parkinsons
epilepsy

21
Q

why BDZ sedation CI in severe respiratory disease?

A

sensitive to respiratory depression

22
Q

medical CI to conscious sedation

A
allergy
systemic disease
resp disease
pregnancy
liver/kidney disese
muscle disease - respiratory depression
obesity - airway control
psychiatric disorders
drug interactions
23
Q

mechanism of action of benzodiazepines

A

act on GABA receptions - inhibitory action

24
Q

undesirable effects of BDZs

A

respiratory depression
elimination problems
hyperactivity in elderly - receptors change with age

25
Q

BDZ which injection can cause thrombophlebitis

A

diazepam (valium) as not water soluble

longer half life than midazolam

26
Q

dosage for flmazenil

A

200ug originally

100ug/min up to 1mg

27
Q

3 most popular oral sedatives

A

nitrazepam
diazepam
temazepam

28
Q

instructions for undergoing sedation

A
light meal no less than 2 hours before
bring a companion 
travel home privately 
take routine meds unless told otherwise
inform if pregnant 
do not drink alcohol that day
do not drive/operate machinery
don't be alone
do not make important decisions
29
Q

why must a chaperone always be present for IV sedation

A

sexual hallucinations

30
Q

how long must pt stay after last injection of BDZ

A

1 hour

31
Q

what value is lowest oxygen saturation should be in iv sedation

A

90% absolute

worried at 94%

32
Q

does nitrous oxide provide any analgesia

A

yes

33
Q

why may mouth opening be a problem after IDB

A

haematoma formation in medial pterygoid

antibiotics need prescribing if diagnosed early