Contraindications (review lecture) Flashcards
teratogenic enough that the patient can’t use them if anyone in their home might get pregnant
finasteride
dutasteride
(5 alpha reductase inhibitors)
combo oral contraceptives (long list)
thromboembolic phenomena
estrogen dependent neoplasms
pregnant
smoking and over 35
caution w/: liver dz, DM, seizures
exemestane can’t be used in
(aromatase inhibitor)
pregnancy- Cat X
premenopausal women
hydrocortisone, cortisone, prednisone, prednisolone, dexamethasone, fluticasone
(corticosteroids)
NO CONTRAINDICATIONS in adrenal insufficiency
estradiol/estriol/estrone
(long list)
thromboembolic disorders
smoking and over 35
breast cancer (estrogen dependent neoplasms)
undiagnosed genital bleeding
liver dz
uncontrolled HTN
pregnancy
Patient’s with sex steroid dependent cancers can’t take
hMG (FSH)
hCG (LH)
(as these increase sex steroid productions)
ergonovine maleate/methylergonovine maleate can’t be given for ______ or if you have ______
NEVER to induce labor
hepatic or renal dz
A diabetic patient with CHF, liver disease, or who might get pregnant (cat C) shouldn’t take _____
“glitazones”
(thiazolidinediones)
Contraindicated in liver injury/ failure
propylthiouracil
mifepristone can’t be used if….
(antiprogestin)
pregnancy
breastfeeding
people taking glucocorticoids
contraindicated to combo these (CV collapse)
mag sulfate
nifedipine
Can’t be given if: sulfa allergy
SULFonylureas
tolbutamide, chlorpropamide, tolazamide
glyburide, glipizide, glimepiride
radioactive iodine
pregnancy
people who lack childcare
Don’t give _____ if the patient has thyroid cancer or a history of pancreatitis
“glutides”
+
exanetide
(GLP-1 agonists)
“gliptins” can’t be given if you have a
(DPP-4 inhibitors)
hx of pancreatitis
carboprost tromethamine can’t be given if you have _______
acute diseases:
cardiac
pulmonary
renal
hepatic
propranolol can’t be taken if you have….
asthma
DM
Oral “dronates” can’t be given if
(bisphosphonates)
pts w/ esophogeal dz
pts who can’t stay upright for an hour
A diabetic patient with renal impairment can’t take
“gliflozin”
SGLT-2 inhibitors
metformin has 5 contraindications
lactic acidosis
hypoxia (related- CHF, COPD)
alcoholism
kidney dz
liver dz
(I think the top 3 all have to do with higher risk for lactic acidosis)
Black box warning for osteosarcoma
caution w/ pts susceptible to osteosarcoma:
pagets
open epiphyses
radiation thx
teriparatide
abaloparatide
rhPTH
