Contraindications (review lecture) Flashcards

1
Q

teratogenic enough that the patient can’t use them if anyone in their home might get pregnant

A

finasteride

dutasteride

(5 alpha reductase inhibitors)

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2
Q

combo oral contraceptives (long list)

A

thromboembolic phenomena

estrogen dependent neoplasms

pregnant

smoking and over 35

caution w/: liver dz, DM, seizures

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3
Q

exemestane can’t be used in

(aromatase inhibitor)

A

pregnancy- Cat X

premenopausal women

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4
Q

hydrocortisone, cortisone, prednisone, prednisolone, dexamethasone, fluticasone

(corticosteroids)

A

NO CONTRAINDICATIONS in adrenal insufficiency

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5
Q

estradiol/estriol/estrone

(long list)

A

thromboembolic disorders

smoking and over 35

breast cancer (estrogen dependent neoplasms)

undiagnosed genital bleeding

liver dz

uncontrolled HTN

pregnancy

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6
Q

Patient’s with sex steroid dependent cancers can’t take

A

hMG (FSH)

hCG (LH)

(as these increase sex steroid productions)

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7
Q

ergonovine maleate/methylergonovine maleate can’t be given for ______ or if you have ______

A

NEVER to induce labor

hepatic or renal dz

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8
Q

A diabetic patient with CHF, liver disease, or who might get pregnant (cat C) shouldn’t take _____

A

“glitazones”

(thiazolidinediones)

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9
Q

Contraindicated in liver injury/ failure

A

propylthiouracil

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10
Q

mifepristone can’t be used if….

(antiprogestin)

A

pregnancy

breastfeeding

people taking glucocorticoids

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11
Q

contraindicated to combo these (CV collapse)

A

mag sulfate

nifedipine

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12
Q

Can’t be given if: sulfa allergy

A

SULFonylureas

tolbutamide, chlorpropamide, tolazamide

glyburide, glipizide, glimepiride

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13
Q

radioactive iodine

A

pregnancy

people who lack childcare

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14
Q

Don’t give _____ if the patient has thyroid cancer or a history of pancreatitis

A

“glutides”

+

exanetide

(GLP-1 agonists)

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15
Q

“gliptins” can’t be given if you have a

(DPP-4 inhibitors)

A

hx of pancreatitis

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16
Q

carboprost tromethamine can’t be given if you have _______

A

acute diseases:

cardiac

pulmonary

renal

hepatic

17
Q

propranolol can’t be taken if you have….

A

asthma

DM

18
Q

Oral “dronates” can’t be given if

(bisphosphonates)

A

pts w/ esophogeal dz

pts who can’t stay upright for an hour

19
Q

A diabetic patient with renal impairment can’t take

A

“gliflozin”

SGLT-2 inhibitors

20
Q

metformin has 5 contraindications

A

lactic acidosis

hypoxia (related- CHF, COPD)

alcoholism

kidney dz

liver dz

(I think the top 3 all have to do with higher risk for lactic acidosis)

21
Q

Black box warning for osteosarcoma

caution w/ pts susceptible to osteosarcoma:

pagets

open epiphyses

radiation thx

A

teriparatide

abaloparatide

rhPTH