Contractile Character of Muscle and Fatigue Flashcards

1
Q

What is an isometric contraction?

A

Contraction generating force without shortening

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2
Q

What is an isotonic contraction?

A

Change in length of the muscle fiber to generate force

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3
Q

What is a concentric contraction?

A

Shortening contraction

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4
Q

What is an eccentric contraction?

A

Lengthening contraction

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5
Q

What four factors determine the contractile characteristic of muscles?

A

Duration of active state
Force-velocity relation
Length-tension relation
Fatigability

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6
Q

What is the latent period?

A

When stimulated muscle processes are underway

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7
Q

Is isotonic or isometric latent period longer?

A

Isotonic

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8
Q

Why is the isotonic latent period longer?

A

Because it has to reduce the slack of tendons and elastic fibers from muscle

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9
Q

What is contraction time?

A

Time to peak tension

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10
Q

What is relaxation time?

A

Time to required for decay of the active state; determined by rate calcium returns to SR

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11
Q

What is described by the length-tension relationship?

A

Muscles at different lengths stimulated will give different tension values

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12
Q

What is described by the force-velocity relationship?

A

A loaded muscle will have a slower contraction velocity than a completely free muscle

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13
Q

What causes the force-velocity relationship?

A

Cross-bridges maintaining the length can not contract; at lesser loads some CBs are left over to shorten the muscle at a slower velocity

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14
Q

What is the ratio of ATP cost for one AP in type I vs type II muscle fibers?

A

1:3

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15
Q

Why are FT muscles more costly?

A

Because they have much faster cross-bridge cycling

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16
Q

What does the Henneman size principle state?

A

That motor units are activated in a fixed order

17
Q

Which size motor neurons are activated first?

A

Smaller motor neurons (Type I)

18
Q

What is a strong predictor of energy cost during walking?

A

The vertical displacement of the pelvis

19
Q

Why is speed decreased in amputees and obese patients?

A

Because the energy expenditure is greater so they must slow down to conserve energy; still use more energy when moving slower

20
Q

What is muscle fatigue?

A

Inability to generate a required force

21
Q

What are the two types of muscle fatigue?

A

Central and peripheral fatigue

22
Q

What is central fatigue?

A

Fatigue that occurs within the CNS to NMJ

23
Q

What is peripheral fatigue?

A

Fatigue that occurs from the NMJ to contractile force generating apparatus

24
Q

What can contribute to muscle fatigue?

A

Hydrogen ion conc. from lactate ion

25
Q

At what concentration of lactate does muscle fatigue typically occur?

A

18 mM

26
Q

What is an example of central fatigue?

A

When a task can not be continued but the muscles can produce the required force when directly stimulated electrically

27
Q

What is a list of factors that are involved in muscle fatigue?

A
Potassium ion
Decreased ATP
Inorganic Pi
Lactate and H+ (mostly H+)
Muscle pH
Muscle Glycogen Depletion
Reactive oxygen species
28
Q

What is the fatigue quotient?

A

Formula that takes into account the influence of the 3 biomechanical systems that are the basis of muscle function

29
Q

How is the value of a fatigue quotient evaluated?

A

The lower the ratio the more fatigue resistant a muscle is