Contraception And Sterilazation Dr. Wootton Flashcards
Hormonal Contraception : Oral Contraceptives
- Combination : E and P
= suppress GnRF which decreases LH and FSH
= Progesterone : suppress LH, suppressing ovulation, thickening cervical mucous
= Estrogen : cycle control stabilizing endometrium an less breakthrough bleeding
Oral Contraceptives pills work how
- 21 days active hormones and 7 days placebo (some are 24 days H and 4 days placebo , shorter bleeding)
- Also continuous were you never bleed
Progesterone only oral contraceptives work how
- How it works
- Ovulation ?
- Who
- How to take it
- Make cervical mucous thick and impermeable
- 40% still have ovulation
- Usually for women who have contraindications to E, or breastfeeding women
- Must be taken same time every day (not more then 3 hours late)
Benefits to Oral Contraception
- Regular menstrual cycle
- Improved painful bleeding = prevents arachodonic production —> PGE
- Lower risk of anemia
- Lower Endometrial and ovarian cancer, benign breast and ovarian cysts (PCOS)
Side Effects of Oral Contraceptions
- Breakthrough bleeding (first 3 mo)
- Amenorrhea (1%)
- MILD : bloating, Weight gain (perceived), breast tenderness, N,F, HA
- SERIOUS : DVT, PE, Cholestasis, Gallbladder dz, MI, Hepatic Tumors
The Patch
- Is what
- How do you apply
- Who
- Side effects
- E + P
- Every 3 weeks to dry clean skin on buttocks, upper outer arm or lower abd
- Not over 198lb
- Greater risk of DVT, and same other side effects as oral
Vaginal Rings
- Are what
- Associated with
- Toleration
- E and P
- Higher compliance because its 1 time a month (insert to vagina for 3weeks) , can be removed for 3hr
- Tolerated since not going through GI and less spotting (not pass through liver)
Annovera Vaginal Ring
- Is what
- Used how
- Side effects
- Newer thicker ring, Segesterone acetate + E
- Leave in for 21 days take out 7 days (13 months use)
- Same as other combination contraceptives
Who can you not use Combination Oral Contraceptives in
- Women over 35 who smoke
- DVT/PE history
- HTN, DM, SLE
- Liver tumors or severe liver disease
- Migraine with aura (youn ps usually)*
Injectable Hormonal Contraceptives
- Also called
- What is it + how good
- How to use it
- MOA
- Depo-Provera ( Depo medroxyprogesterone acetate) = Progesterone only
- P , very good , not altered by weight
- Inject every 11-13 weeks (P level stays for 14 weeks), first 5 days of menses is when you should inject
- Thickens cervical mucosa, decidualization of endometrium, blocks LH surge and ovulation
Depo PRovera injections side effects 5
- Bone metabolism (due to low E from no ovulation)
- Black box for use over 2 years
- Real Weight gain
- Irregularly bleeding *
- Exacerbate depression
Depro PRovera decrease risk of what + others who use it
- Endometrial hyperplasia + Sickle Cell crisis
2. Women that cant take E, breastfeeding, effective contraception, endometriosis
When to NOT give Depo Prevera
- Suspected Pregnancy
- Unevaluated Vaginal bleeding
- Breast malignancy
- DVT current
- Liver dysfunction
Long Acting Reversible Contraceptives (LARCS) 2 types
- Implants
2. IUDs
Nexplanon
- Is what
- Used how
- MOA
- Single radiopaque rod implant 68mg E(4cm long 2mm diameter) = Progesterone*
- For 3 years (within 5 days of menses preferred to implant)
- Cervical thickness, Inhibit ovulation
Nexplanon side effects
- Irregular Vaginal bleeding *
- Vaginitis
- Acne
- Breast pain
- HA
- Weight gain
Nexplanon who
- Very effective
2. Breast feeding
Contraindications of Nexplanon
- Suspected pregnancy
- Current DVT
- Liver tumor one active liver dz
- Abnormal bleeding not dx
- Suspected breast cancer
What can happen at Nexplanon site of implantation
- Infection (if you don’t take bandage off)
- Bruising
- Deep insertion, migration
- Persistent pain
IUD 5 available
- Paragard (Cooper T)
- Mirena / Liletta
- Skyla / Kyleena
= insertion in office
Risks of IUD
- Infection in forest 20 days
- Ectopic Pregnancy
- Uterine perforation at time of insertion (laparoscopic removal needed)
- Malposition (hysteroscopy for removal)
Contraindications for IUD
- Breast cancer (you CANT use Levonorgestrel)
- Sepsis or chorioamnionitis recent
- Cervical inf
- Septic abortion
- Wilsons Dz (Cooper T)
- Uterine malformations like fibroids or uterine septums
Mirena
Kyleena, Liletta, Skyla how long you use it , what hormone they have
- Mirena : 7 years
- Kyleena : 5 years
- Liletta : 7 years
- Skyla : 3 years (smallest size)
= highly effective
= ONLY Progesterone (Levonorgestrel) **
Benefits of Levonorgestrel IUDs
- Decrease bleeding (50%)
- Lower painful periods
- Protection of endometrial lining from unopposed E
- Long term