Contraception Flashcards
List of contraception options other than condoms?
> Combined hormonal contraception:
- Pills, patch, vaginal ring
> Progesterone only methods:
- Pill, injectable, implant
> Intrauterine contraception
> Emergency contraception
> Sterilisation
Between 16-49 what is the most commonly used contraception?
1) Sterilised (male or female) = 28%
2) Combined hormonal contraception (CHC) = 25%
3) Intrauterine methods (coil) = 6%
4) Progestogen-only pill (POP) = 5%
5) Progestogen-only implants or injectable = 3%
Which percentage of women aged 16-49 years old who are sexually active and not planning pregnancy are not using contraception?
12%
What does the ideal contraception have?
> 100% reversible
100% effective
100% unrelated to intercourse
100% free of adverse side-effects
100% protective against sexually transmitted infections
Non-contraceptive benefits
Low maintenance, no ongoing medical input
Which contraceptive options are 100% reversible?
> All except sterilisation
> Only delayed reversal is injectables
Which contraceptive options are 100% effective?
None - however, best is the vasectomy followed by implant
Which contraceptive options are 100% unrelated to intercourse?
All except condoms
Which contraceptive options are 100% free of adverse effects?
None
Which contraceptive options are 100% protective against STIs?
Not even condoms
Which contraceptive options have non-contraceptive benefits?
Combined hormonal contraception (CHC) and IUS
Which contraceptive options have low maintenance, no ongoing medical input?
Implant or IUT
What is the pearl index?
ThePearl Indexis defined as the number of contraceptive failures per 100 women-years of exposure. It looks at the total months or cycles of exposure from the initiation of the product to the end of the study
What is the life table analysis?
Life Table Analysis provides the contraceptive failure rate over a specified time-frame and can provide a cumulative failure rate for any specific length of exposure.
What is method failure?
Pregnancy despite correct use of method by user
What is user failure?
Pregnancy because method not used correctly by user
What is the advantage of using long-acting reversible contraception (LARC)?
Minimises user input and so minimises user failure rates
Which type contraception with perfect use has the worst efficiency - percentage of women experiencing an unintended pregnancy within the year of use?
1) Cervical cap (Parous woman) = 26%
2) Spermicides = 18%
3) Cervical cap (Nulliparous woman) = 9%
Which type contraception with typical use has the worst efficiency - percentage of women experiencing an unintended pregnancy within the year of use?
1) Cervical cap (Parous woman) = 32%
2) Spermicides = 29%
3) Withdrawal = 27%
Which type contraception with perfect use has the best efficiency - percentage of women experiencing an unintended pregnancy within the year of use?
1) Progesterone implant = 0.05%
2) Levenorgestrel intrauterine system = 0.1%
3) Combined pill and minipill/ Combined hormone patch/ injectable progesterone = 0.3%
Which type contraception with perfect use has the worst efficiency - percentage of women experiencing an unintended pregnancy within the year of use?
1) Progesterone implant = 0.05%
2) Levenorgestrel intrauterine system = 0.1%
3) Male sterilisation = 0.15%
Which days does someone usually ovulate?
12-18 days
How long does the egg survive following ovulation?
24 hours
How long do most sperm survive?
Most sperm survive less than 4 days (5% may survive 7 days)
When is the highest chance of getting pregnant and why?
Days 8-19, because:
1) Ovulation usually occurs 12-18days (2 weeks before period)
2) Sperm survives less than 4 days usually
3) Eggs survive 24 hours
Which two hormones are within the combined hormonal contraception (pill, patch vaginal ring)?
1) Ethinyl estradiol
2) Synthetic progesterone
What can patch EVRA cause?
<5% have a skin reaction
How often is the patch EVRA changed?
Once weekly
How often is ring nuvaring changed?
Every 3 weeks, it can be taken out for 3 hours in 24 hours so some may take it out for sex
How does the combined contraceptive hormones work?
Negative feedback on the female HPG axis (Hypothalamus and anterior pituitary) stops the release of LH and FSH.
Therefore, ovulation is inhibited and also affect cervical mucus and endometrium.
What are the non-contraceptive benefits of the combined hormonal contraceptives?
> Regulate/reduce bleeding- help heavy or painful natural periods
> Stop ovulation- may help premenstrual syndrome
> Reduction in functional ovarian cysts
> 50% reduction in ovarian and endometrial cancer
> Improve acne / hirsutism
> Reduction in benign breast disease, rheumatoid arthritis, colon cancer and osteoporosis
What are the “troublesome” (not serious risks) side effects of the combined hormonal contraceptive?
> Breast tenderness > Nausea > Headache > Irregular bleeding first 3 months > Mood ? Causal or other life events > Weight gain- not causal
What are the serious risks side effects of the combined hormonal contraceptive?
> Increased risk of venous thrombosis (DVT and PE)
Increased risk of arterial thrombosis (MI and ischaemic stroke)
Increased risk of cervical cancer
Increased risk of breast cancer
In terms of increased venous thrombosis risk who shouldn’t take the combined hormonal contraceptive?
> If BMI >34
Previous venous thrombosis (VTE)
1st degree relative with VTE under 45
Thrombophillis
In terms of increased arterial thrombosis risk who shouldn’t take the combined hormonal contraceptive?
> Smoker >35 years old > Previous arterial thrombosis > Focal migraine > Age >50 years old > Hypertension 140/90 mm Hg
In terms of past GI pathologies who shouldn’t take the combined hormonal contraceptive?
> Gall bladder disease
> Previous liver tumour
How long does it take of not taking the combined hormonal contraceptive to return the risk of breast cancer back to normal?
10 years off
In absolute terms the risk of VTE increases from - general population?
5 per 100,000
In absolute terms the risk of VTE increases from - Combined oral contraceptive population?
15 per 100,000