Contraception Flashcards
what contraception acts at the ovary
Combined hormonal contraception
Progesterone-only pill
Injection
Implant
what contraception acts at the endometrium
IUS
IUD
what contraception acts at the cervix
IUS
Progesterone-only pill
CHC
what is the mode of action of the combined hormonal contraction
Inhibits LH and FSH this prevents ovulation
Thickens cervical mucus this acts as a natural sperm barrier
Thins endometrium this prevents implantation
what is the failure rate of the combined hormonal contraception
- If used perfectly 0.3 per 100 woman years
- If used typically 9 per 100 woman years
what are the time of the combined hormonal contraception
- birth control pill
- vaginal ring
- brith control patch
what are the advantages and disadvantage of the combined contraceptive pill
advantages
- Reduce menorrhagia / dysmenorrhoea / PMS
- Reduce risk of PID
- Reduce risk of benign ovarian tumours / colorectal cancer / ovarian cancer
- Improve acne
- May reduce risk of fibroids, ovarian cysts and non-cancerous breast disease
disadvantages
- Higher risk of VTE / stroke / CV disease
- Increased risk of breast cancer (returns to normal 10 years after stopping)
- Small increased risk of cervical cancer
- Depression / low mood
- Temporary side effects include headache, nausea, breast tenderness, mood changes
- Breakthrough bleeding
what publishes the UKMEC guidelines
FSRH
what does a UKMEC 1 condition mean
- a UKMEC 1 condition means it is fine to take that form of contraception with the disease
what does an UKMEC 4 mean
this means that you should not take the contraception with that condition
what are the UKMEC 4 conditions for the combined contraception pill
- VTE / CV disease (inc atrial fibrillation) / stroke – either personal or close family history
- Hypertension
- Any thrombophilic condition
- Oestrogen-dependent cancers (usually breast or cervical)
- Migraine with aura – slightly higher risk of stroke with hormonal contraception
- Liver disease
- Combination of risk factors for cardiovascular disease, e.g. hypertension/diabetes
- Over 35 years and a smoker
- BMI > 35
- < 6 weeks postpartum if breastfeeding – it can mess with postpartum hormone regulation
- <3 weeks postpartum if non-breastfeeding
what is the mode of action of progesterone
- Thickens cervical mucus this act as a natural sperm barrier
- Thins endometrium prevents implantation
- Inhibits ovulation (97% desogestrel, 60% others
what is the failure rate of progesterone only contraception
If used perfectly 0.3 per 100 woman years
If used typically 9 per 100 woman years
what are the types of progesterone only contraception
POP Injection (Depo-Provera) - lasts 3 months Implant (Nexplanon/Implanon) - lasts 3 years Intrauterine system (IUS) - lasts 5 years
what is the advantages and disadvantages of the progesterone
Advantages
- Reduces menorrhagia / dysmenorrhoea / PMS
- Amenorrhoea
- Reduce risk of endometrial cancer
- Can be used when breastfeeding
- Fewer adverse effects compared to CHC
disadvantages
- Irregular spotting
- Acne
- Headaches, nausea, mood swings, bloating, breast tenderness, weight gain
- Ovarian cysts
- All above usually settle after 6 months
- IUS only – uterine perforation, expulsion, ectopic pregnancy, PID
what are the UKMEC 4 diseases for progesterone pill only
- Unexplained vaginal bleeding
- If VTE / stroke / IHD occur during use
- Breast cancer
- Severe liver disease
- IUS only – PID, >48h - <4w postpartum