Contra Flashcards
GI protectant
Renal failure - aluminum toxicity
Prostaglandin
Pregnancy- causes abortion
Chemical stimulants
Acute abdominal disorders
Bulk stimulants
Acute abdominal disorders
Osmotic laxatives
Acute abdominal disorders, appendicitis, surgical, fecal impaction, intestinal obstruction
Lubricant
Acute abdominal disease
GI stimulants
GI obstruction
Phenothiazines
CNS depression, severe hypotension or hypertension, severe liver dysfunction
Interferons
Pregnancy and lactation
Interleukin
Pregnancy and lactation
Colony stimulating factors
Pregnancy and lactation, renal and hepatic disease, radiation and chemotherapy will inhibit colony effects
Immune modulators
Severe hepatic impairment
Pregnancy and lactation
T and B suppression
Hepatic dysfunction
Interleukin antagonists
Allergy to E. coli , renal, infection, immunosuppression
Monoclonal antibodies
Fever
Fluid overload
Salicylates
Abnormal bleeding
NSAID
allergy to sulfa or salicylate, HTN, peptic ulcer, GI bleed
Gold compound
DM, CHF, renal/hepatic, blood dyscrasias, pregnancy and lactation -
Increased toxicity of gold compounds
TNF
Acute infection, cancer, sepsis, TB, hepatitis, myelosuppression, demyelination-
Contra due to TNF suppressing immunity thus making it hard to fight of infection
Glucocorticoids
Acute infection, lactation
Mineralocorticoids
HTN, CHF, cardiac disease-
Due to corticoid causing increased blood volume
Antitussive
Patients who need to cough- like pneumonia
Relative- head injury and CNS suppression, respiratory conditions
Topical nasal decongestant
Conditions that might exacerbate due to increase in SNS (prostate and glaucoma)
Legion in mucous membranes can cause systemic absorption
Oral decongestants
Caution with conditions that can exacerbate due to increase SNS
Topical nasal steroid decongestant
Acute infection
Antihistamine
Caution with renal and hepatic, arrhythmia
Mucolytics
Caution with bronchospasm, peptic ulcer, esophageal varices
Leukotriene receptor antagonists
Not for acute asthma attack
Nitrates
Severe anemia, head trauma, ED pills, pregnancy and lactation
Beta blockers
Bradycardia, heart block, cardiogenic shock, asthma and COPD, pregnancy and lactation
Ca block
Heart block, sick sinus, renal and hepatic, pregnant and lactating
Cardiac glycosides
Ventricular tachycardia or fibrillation, heart block, sick sinus, acute MI, renal, electrolyte
Phosphodiesterase inhibitors
Severe aortic or pulmonary disease, MI, fluid volume deficiency, ventricular arrhythmia
HCN block
HF, hypotension, sick sinus, AV block, bradycardia, pacemaker, hepatic
Class 1
Bradycardia, heart block, CHF, hypotension, electrolytes
Class 2
Sinus Bradycardia, AV block, cardiogenic shock, CHF, asthma and respiratory depression, pregnant and lactation
Class 3
Caution with shock, hypotension, respiratory depression, prolong qt, renal and hepatic
Class 4
Sick sinus, heart block, bradycardia, pregnancy and lactation, CHF, hypotension