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Pharmacology 2 > Adverse > Flashcards

Adverse Flashcards

1
Q

H2 antagonists

A

GI, CNS
HypoT, arrhythmias

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2
Q

Antacids

A

Rebound acidity
Alkalosis
Constipation, diarrhea
HyperCa, hypophosphatemia

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3
Q

PPIs

A

CNS, GI
Upper respiratory: cough, stuffy, hoarse, epistaxis (nosebleed)

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4
Q

GI protectant

A

GI, CNS
Dry mouth

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5
Q

Prostaglandin

A

Mainly GI
GU (increased bleed, irregular menses)
Causes abortions

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6
Q

Digestive enzymes

A

GI
Abnormal electrolytes

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7
Q

Chemical stimulants

A

GI, CNS
Sweat, palpitations, flushing, fainting
Cathartic dependence
(Castor oil) blocks fat soluble vitamin absorption

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8
Q

Bulk stimulants

A

GI, CNS
Sweat, palpitations, flushing, fainting

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9
Q

Osmotic laxatives

A

GI, CNS
Sweat, palpitations, flushing, fainting
Dehydration, dry mouth

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10
Q

Lubricants

A

GI, CNS
Sweat, palpitations, flushing, fainting
(Mineral oil) leakage and staining

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11
Q

GI stimulants

A

GI
CV (decreased BP and HR)
Weakness, fatigue

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12
Q

Antidiarrheal

A

GI
Fatigue, weak, dizzy

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13
Q

Phenothiazines

A

CNS, photophobia
CV: hypoT, hyperT, arrhythmia
GU: menstrual disorders, galactorrhea (milk), gynecomastia (swelling)

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14
Q

Nonphenothiazines

A

CNS
Extrapyramidal (involuntary movements): dystonia (spasms), akathisia (restless), dyskinesia (jerky movements), parkinsonism (slowness and rigidity)

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15
Q

5-HT3 Receptor Blockers

A

HA, dizzy,
myalgia (muscle pain),
constipation

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16
Q

Substance P/Neurokinin 1 receptor antagonists

A

Anorexia, constipation, diarrhea,
increased liver enzymes,
dehydration, fatigue

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17
Q

Interferons

A

Most common: lethargy, myalgia, arthralgia
Nausea
HA, dizzy
Anorexia
Bone marrow depression

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18
Q

Interleukins

A

Most common: flu like symptoms (lethargy, myalgia, arthralgia, fatigue, fever)
Respiratory difficulties, depression with suicidal thoughts

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19
Q

Colony stimulating factors

A

Most common: generalized pain and bone pain
GI
HA, fatigue, weakness
Alopecia
Dermatitis (eczema)

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20
Q

Immune modulators

A

Unknown

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21
Q

T and B suppressors

A

Increased risk of infection
Increased risk of neoplasm (tumor)
Hepatotoxicity
Renal toxicity and dysfunction
Pulmonary edema

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22
Q

Interleukin antagonist

A

Nausea, diarrhea
HA
Sinusitis

23
Q

Monoclonal antibody

A

Flu like
Pulmonary edema
Fluid retention

24
Q

Salicylates

A

Stomach and clotting
Do not use for fever for kids- Reye Syndrome

25
Q

NSAID

A

GI, GI pain and bleed
Dyspepsia (indigestion)
Somnolence (drowsy), dizzy
Platelet inhibition
HTN
Bone marrow suppression with chronic use

26
Q

Acetaminophen

A

HA
Fever
Rash
Anemia
Renal dysfunction
Hepatotoxic with OD and chronic use

27
Q

Gold compounds

A

Stomatitis/glossitis/gingivitis
Bone marrow depression
Dermatitis
Interstitial pneumonia
Anaphylactic shock

28
Q

TNF blockers

A

Risk of fatal infection and development of lymphoma and cancer

29
Q

Glucocorticoid

A

Increase glucose
Lots: GI, CNS, HF, fluid retention, osteoporosis, frail skin that won’t heal quickly
Cushing
Impaired child growth

30
Q

Mineralocorticoids

A

Increase fluid volumes
HypoK

31
Q

Antitussives

A

Dries mucous membranes
CNS drowsy, HA, dizzy
GI nausea, constipation

32
Q

Topical nasal decongestant

A

Sting and burn
Rebound congestion
SNS effects

33
Q

Oral decongestants

A

Rebound congestion
SNS effects

34
Q

Topical nasal steroid decongestants

A

Burn and sting
Dry mucous membranes
HA
Decreased healing

35
Q

Antihistamines

A

CNS drowsy
Anticholinergic dry, nausea, urine hesitation
CV arrhythmia

36
Q

Expectorants

A

GI
CNS HA and dizzy
Rash
Masking

37
Q

Mucolytics

A

GI
Stomatitis
Rhinorrhea (runny nose)
Bronchospasm
Rash at nebulizer area

38
Q

Xanthines

A

GI
Irritated
Tachycardia
Hyperglycemia
Seizure
Brain damage and death

39
Q

Sympathomimetics

A

SNS
CNS
GI
Bronchospasm
Cardiac - arrhythmia, hypertension, sweat, pallor, flushing

40
Q

Anticholinergic

A

Can’t see spit poop pee
CNS dizzy, HA, nervous, fatigue, sore throat, retention, palpitations

41
Q

Inhaled steroids

A

Sore throat, hoarseness, coughing
Dry mouth, throat infections

42
Q

Leukotriene receptor antagonists

A

URI, pharyngitis, cough
CNS dizzy and HA
GI and increased liver enzymes
Pain, fever, myalgia
Grouchy kids

43
Q

Lung surfactants

A

Unknown

44
Q

Nitrates

A

Related to vasodilation and decreased blood flow
2 biggies: Hypotension and HA
Also GI, flush, pallor, sweat

45
Q

Beta blockers

A

Related to SNS blocking
Hypotension and bradycardia
GI
CNS dizzy, fatigue, depression
CV CHF, decreased CO, arrhythmia
Respiratory- bronchospasm, dyspnea, cough

46
Q

Calcium channel blockers

A

Most common: hypotension, arrhythmia
GI
Skin
HA

47
Q

Cardiac glycosides

A

CNS HA, weak, drowsy, yellow halo
GI anorexia
Brady arrhythmias

48
Q

Phosphodiesterase inhibitors

A

Most common: arrhythmias, hypotension, GI, thrombocytopenia (reduced platelets)

49
Q

HCN channel blockers

A

Biggest one: bradycardia
HyperT, atrial fibrillation, luminous phenomena (sudden vision changes)

50
Q

Class 1

A

CNS dizzy and fatigue (common), slurred
GI nausea and vomiting
CV arrhythmia (common)
Respiratory depression
Rash, hair loss, potential bone marrow suppression

51
Q

Class 2

A

Related to SNS block
CNS dizzy, insomnia, dream, fatigue (common)
CV hypotension and bradycardia (common), AV block, arrhythmia
Respiratory bronchospasm and dyspnea
GI nausea, vomiting, anorexia
Decreased libido and exercise tolerance
Altered blood glucose

52
Q

Class 3

A

GI nausea and vomiting
CNS weak and dizzy
CV arrhythmia

53
Q

Class 4

A

Common: dizzy, weak, fatigue
Depression
GI
HypoT, CHF, shock

Pharmacology 2 (5 decks)

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