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Tissues of the body > Connective tissues > Flashcards

Connective tissues Flashcards

1
Q

Tendons connect …… to …..

A

It connects muscle to bone

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2
Q

Ligaments connects ….. to ….

A

It connects bone to bone

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3
Q

How does connective tissue vary? (3)

A
  • Types of cells
  • Abundance/density of cells
  • Constitution of the ECM
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4
Q

What are the three types of regular connective tissue?

A
  • Loose or areolar connective tissue
  • Dense irregular connective tissue
  • Dense regular connective tissue
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5
Q

What is the function of GAGs in the ground substance?

A

They are highly negatively charged and this attracts water creating a gel to which fibres and cells can embed

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6
Q

Ground substance is composed of ….. , ……. and …….

A

Glycosaminoglycans (GAGs), proteoglycans and glycoproteins

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7
Q

Most collagen is which type of collagen?

A

Type 1 collagen

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8
Q

Type 3 fibres are also known as ……

A

Reticulin

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9
Q

Which type of collagen is found in the basal lamina of the basement membrane?

A

Type IV

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10
Q

Which amino acid found in elastic fibres make them stretchy?

A

Lysine

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11
Q

What are the three components of elastic fibres?

A

Anamorphous protein, elastin and fibrillin

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12
Q

What is the function of fibroblasts?

A

To lay down collagen, elastin and reticulin

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13
Q

What are macrophages?

A

They are antigen-presenting phagocytes often found in connective tissue

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14
Q

Mast cells contain granules containing what?

A

Histamine and heparin

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15
Q

Areolar connective tissue is found in which four places?

A

Deep under the skin, the submucosa, the peritoneum and blood vessels

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16
Q

Reticular tissues forms lymph nodes and …….

A

Frameworks in the liver

17
Q

Name the two main places dense regular tissue is found.

A

Tendons and ligaments

18
Q

What type of connective tissue is found in the dermis?

A

Dense irregular connective tissue

19
Q

How can you stain elastic fibres?

A

With a silver stain

20
Q

What is Marfan’s syndrome?

A

A mutation to the fibrilin gene which affect elastic fibres. You are at risk of aortic rupture and frequent joint dislocation. Sufferers are abnormally tall and exhibit arachnodactly

21
Q

What is systemic sclerosis?

A

It is when organs have excessive accumulation of collagen

22
Q

What are the symptoms of scurvy?

A

Teeth falling out

23
Q

Where is the nucleus positioned in brown adipose tissue?

A

Centrally

24
Q

Ehlers- Danlos disease is a deficiency in…..

A

Collagen type 3 or reticulin

25
Q

What is connective tissue?

A

Connective tissue is tissue of mesodermal origin with three basic components- cells, extracellular fibres and ground substance

Tissues of the body (17 decks)

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