Connective Tissue Disease 4 - Sjogrens Flashcards by Ryan Govier | Brainscape

Q

What is Sjogrens syndrome and what are the types?

A

Dry eyes and mouth

Primary - Absence of any other CTD

Secondary - Associated with others, usually RA

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Q

Who tends to get it?

A

Middle aged females

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Q

What is the pathophysiology?

A

Lymphocyte infiltration into exocrine glands

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Q

What are the main symptoms

A

ANY CTD ASSOCIATED SYMPTOMS

Lacrimal infiltration and dry eyes

Parotid infiltration and dry mouth

Dyspareunia

Dy skin

Parotitis

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Q

What does Sjogrens increase your risk of?

A

Lymphoma

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Q

What is this?

A

Parotitis

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Q

What are the investigations for it?

A

Eye examination - ?Corneal abrasions

Schirmer test

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Q

What are the serological tests?

A

ANA as in all CTD

RF if secondary

Anti Ro/LA

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Q

What is the treatment?

A

Generally supportive

Artificial tears

sugarfree gum to stimulate salivary glands

Immunosuppression if systemic

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