Connective Tissue Flashcards
Collagen fibres
Are thick , tough, fibrous proteins that do not branch .
What are the most abundant fibers?
Collagen fibres
What is the role of fibroblast?
To synthesis all of the collagen, elastic and reticular fibers.
Describe type 1 collagen fibers
Type 1 fibers are found in the dermis of skin, tendons, ligament and bone. They are strong and offer great resistance to tensile stresses
Describe type 2 collagen fibres
Present in hyaline cartilage and elastic cartilage. The fibres provide great resistance.
Describe type 3 collagen fibres
They are him, branching reticular fibres that form the delicate supporting mesh work in such organs such as lymph nodes, spleen and bone marrow
Describe type 4 collagen fibres
Present in the basal lamina of the base membrane which the basal regions of the cells are attached.
Reticular fibres
Consist of main type 3 collagen fibres are thin and form a delicate netlike framework in the liver, lymph nodes, spleen , hemopiotic tissue.
Loose connective tissue
Loose irregular arrangement of connective tissue fibres and ground substances. Matrix contains numerous connective tissue cells and collagen fibres.
Dense connective tissue
Consist of densely packed collagen fibres and fibroblast. The collagen fibres are arranged randomly.
Where does collective tissue develop from?
Mesenchyme
What is mesenchyme?
Embryonic tissue
What does the extra cellular matrix contain?
Connective tissue fibres, ground substances within which are embedded the different protein fibres .
Function of connective tissue
Binds, anchors, and supports various cells, tissues and organs
Name the components that connective tissue consist of
Cells, extra cellular material, fibres
Fibroblast shape and importance
Are fusiform shaped, synthesizes all the components of the connective tissue including collagen, reticular and elastic fibres. Also synthesises carbohydrates such as glycoaminoglycans, proteoglycans and glycoproteins of the extra cellular matrix.
Fibrocytes
Are smaller than fibroblast, are spindles shaped and are mature and less active cells.
Adipose tissues
Singly or in groups
Cells store fat cells
In permanent slides cells look empty.
Function of the adipose tissue
To provide packing material in organs
Mast cells
Associated with blood vessels.
Synthesis and release histamine and heparin.
Histamine
A potent mediator of inflammation . It dilates blood vessels , increases permeability to fluid thereby causing edema and induces signs and symptoms of immediate hypersensitive reactions.
Structure of mast cells
Spherical cell, filled with fine regular basophillic granules.
Plasma cells
Arise from the lymphocytes and give rise to antibodies
Leukocyte a
Defend the body against diseases. Neutrophils Basophils Monocytes Lymphocytes Macrophages Eosinophils
Macrophage
Phagocytic in nature, sometimes the cytoplasm show ingested material.
Elastic fibres
Thin, small, branching, allow steching, contains protein.
Where are elastric fibres found?
Bladder, lungs, and skin. Walls of the aorta and pulmonary trunk,
Which cells synthesis elastic fibres in the large vessels?
Smooth muscle
Reticular fibres
Are thin, form a delicate net, in liver, spleen and lymph node.
Which type of reticular fibres are in reticular fibres?
Type III
Function of reticular fibres
They support capillaries, nerves and muscle cells.
What are the two types of connective tissues?
Loose connective tissue and dense connective tissue
Loose connective tissue is dived into two group . What are they?
Irregular and regular
Extracellular matrix
Is amorphous ( having no shape), gel like, contains glycoaminoglycans, proteoglycans and glycoproteins. Extra cellular matrix contains type 1 collagen.
Loose connective is also known as?
Areolar
Dense irregular tissue is found in?
Mammary gland
Dense regular tissue in found in ?
Tendon
Functions of connective tissue
Provides supportive matrix Repairs injuries It forms planes which contains neuro vascular bundles Form major part of superficial fascia Modified as deep fascia.
