Connective tissue Flashcards

1
Q

State the 3 types of fibers.

A
  1. Reticular
  2. Collagen
  3. Elastic
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2
Q

Which type of fiber is the most abundant?

A

Collagen

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3
Q

Why can collagen be called a glycoprotein?

A

Because the hydroxylsyl amino groups have sugars attached to them.

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4
Q

Where is loose areolar connective tissue found?

A

Underneath epithelium

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5
Q

Which kind of fibers are found in loose areolar connective tissue?

A

Collagen

Elastic

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6
Q

What is the difference between dense regular and dense irregular connective tissue?

A

Dense regular fibers arranged regularly
Dense regular found in areas of mechanical stress (tendons and ligaments)

Dense irregular fibers haphazardly arranged
Not found in areas of mechanicl stress

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7
Q

Name the 3 types of cartilage.

A

elastic
hyaline
fibrocartilage

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8
Q

Which cartilage does not undergo calcification?

A

Elastic

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9
Q

How can you differentiate reticular connective tissue from areolar connective tissue?

A

Reticular connective tissue does not stain well with H&E so stained with silver salts and has black appearance; areolar stains with H&E so has a pink color

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10
Q

How are the types of collagen classified?

A

By the combination of alpha chains.

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11
Q

What’s the difference in the functions of type 1 and type 2 collagen?

A

Type 1: provides resistance to force, stretch, and tension

Type 2: provides resistance to pressure

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12
Q

Where is type 1 collagen found?

A

skin, bone, tendons, ligaments, fascia, sclera, dentine (beneath the enamel of teeth)

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13
Q

Which collagen molecule is involved in Osteogensis Imperfecta?

A

Type 1 collagen

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14
Q

What is the cause of Osteogenesis imperfecta?

A

mutation in genes coding for collagen alpha helices that causes blue sclera, hearing loss, and repeated fractures after minor trauma

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15
Q

Which kind of cells are found in both elastic and hyaline cartilage?

A

chondroblasts and chondrocytes

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16
Q

What kind of cells are found in fibrocartilage?

A

fibroblasts and chondrocytes

17
Q

Which cartilage lacks a perichondreum?

A

fibrocartilage

18
Q

Which cartilage has collagen type 2?

A

All of them.

19
Q

True or false: Elastic cartilage has collagen type 1 and 2.

A

False. Fibrocartilage has collagen type 1 and 2

20
Q

How can you differentiate between elastic and hyaline cartilage on a slide?

A

Hyaline cartilage fibers are not visible so matrix appears smooth. Elastic cartilage, fibers are clearly seen. If the slide is not zoomed in, then both cartilages look similar.