Connective Tissue Flashcards
the fluid component of blood
plasma
a tissue, the major constituent of which is extracellular matrix
connective tissue
osteoid matrix- over 90% collagen type 1 embedded in a ground substance of proteoglycans, condroitin, keratin, and hyaluronic acid. Mineralized with calcium phosphate as _______
hydroxyapatite
extracellular material between cartilage cells
chondroid matrix
or ground substance
polysaccharides formed or repeating disaccharide sub-units composed of ironic acid and hexosamine
glycosaminoglycans
a hexose with the primary hydroxyl group oxidized to form an acid
uronic acid
a hexose with an amino acid attached
hexosamine
in glycosaminoglycans, ironic acid, and hexosamine, ______ is the predominant molecular component
carbohydrate
protein core with many glucosaminoglycans attached
proteoglycan molecules
hyaluronic acid core with many proteoglycans attached
proteoglycan aggregates
most abundant protein in the human body
collagen
type of collagen that is most common, found in every connective tissue, forms tendons and ligaments
type I
type of collagen that is found only in hyaline and elastic cartilage and in the vitreous body of eye
type II
type of collagen that is found in reticular fibers, healing wounds, smooth muscle, fetal skin, support for cellular structure of some organs such as the liver and spleen.
Type III
type of collagen that is found in the basal lamina of epithelia
type IV (4)
type of collagen that is found in placental basal laminae, tendon, and muscle sheaths
type V
stained black by silver salts
agyrophillic
- forms a network of fibers
- type III collagen
- stained black by silver salts
- important in anchoring small blood vessels to surrounding tissue
- in smooth muscle
reticular fibers
- form broad, wavy diffuse stained bundles
- bundles branch and fuse forming a network
- yellow in living tissue
- protein elastin makes it yellow and elastic
elastic fibers (thinner that collagen fibers in pics)
- actively involved in secretion of extracellular matrix (ground substance) and in fiber formation, usually collagen
- associated with most CT
- involved in woud healing, if absent, wound will not heal
- grow easily in tissue culture (too easily)
fibroblast
macrophages are derived from
monocytes
- many are present in Loose CT
- actively phagocytic
- derived from monocytes
macrophages
- form embryonic connective tissue cells
- resemble fibroblasts, but smaller
- along capillaries and called pericytes
mesenchymal cells
- form 3 dimensional networks of cells that are in contact via long processes
- may be phagocytic
- precursonrs for blood stem cells
- function in immune response
- reticular cells
wandering cells that contain basophilic granules composed of heparin (a sulfated glycosaminoglycan) as well as other pharmacological agents such as histamine. important in allergic reactions
mast cells
antibody producing B lymphocytes
plasma cells