Connective Tissue Flashcards
Large, oval, or round connective tissue cells.
Cytoplasm is filled with basophilic secretory granules
Mast cells
Phagocytosis of bacteria
Neutrophilic leukocytes
[microscopic type of bone]
-first bone tissue to appear in embryonic development and fracture repair
- irregular array of collagen fibers
Primary / Woven bone
tissue intermediate between dense connective tissue and hyaline cartilage
Fibrocartilage
Provide a matrix that joins other tissues and cells
Connective tissues
Production of cytokineses, chemotatic factors, and several other molecules that participate in inflammation (defense), and antigen processing and presentation
Macrophage
Kupffer Cell
Microglial Cell
Components of connective tissues
Cells
Fibers
Ground substance
[type of cells]
found in cavities (lacunae) between layers (lamellae) of bone matrix
Osteocytes
- key regulators of the body’s energy metabolism
- largest repository of energy
- poor heat conductor, contributes to the thermal insulation of the body
- act as shock absorbers
Adipose tissue
Antibodies
Plasma cells
Types of dense connective tissue
Dense irregular
Dense regular
Storage of neutral fats
Adipocytes
types of bone
macroscopic & microscopic
macroscopic:
- compact bone
- spongy / cancellous bone
- long bones
- short bones
microscopic:
- primary / woven bone
- secondary / lamellar bone
Pharmacologically active molecules
Mast cells & basophilic leukocytes
Antigen processing and presentation
Langerhans cell Dendritic cell
[macroscopic type of bone]
spongy with thin layer of compact bone
Epiphyses
- irregular surfaces with pleats, protrusions, and indentations
- a morphologic expression of their active pinocytotic and phagocytotic activities
macrophages / monocyte
types of long bones
epiphyses
diaphyses
[type of cells]
multi-nucleated giant cells involved in the resorption and remodeling of bone tissue
Osteoclasts
Phagocytosis of ECM components
Antigen processing and presenation to immune cells
Secretion of growth factors
Macrophages
Osteoclast
Digestion of bone
ECM is composed of different combinations of protein fibers?
Identify.
Collagen
Reticular
Elastic
composed of mostly type I collagen
Fibrocartilage
[macroscopic type of bone]
composed of compact bone, with a thin component of spongy bone
diaphyses
Large, ovoid cells
Have a basophilic cytoplasm
Plasma cells
Types of connective tissues
Adult:
Loose / Areolar
Dense
Specialized
small canal containing blood vessels, nerves, and loose connective tissue
Osteon / Haversian system
Embryonic tissue formed by elongated undifferentiated cells
Mesenchymal cells
Synthesize collagen, elastin, glycosaminoglycans, proteoglycans, multi-adhesive glycoproteins, and ECM components
Fibroblasts
Supports many structures which are normally under some pressure and low picture
Loose connective tissue
Argyrophilic; PAS positive
Reticular fibers
also called as brown fat
brown adipose tissue
Consists of reticular fibers of type III colagen
Reticular tissue
found mainly in the umbilical cord (Wharton’s jelly) and fetal tissues
Mucous tissue
Most common cells in connective tissue
Fibroblasts
Most abundant protein in the human body
Collagen fibers
Originated from mesenchyme
Connective tissues
specialized for long-term energy storage
white adipose tissue
- supports fleshy structure
- protects vital organs
- reservoir of calcium and phosphate
bone
matrix cavities in which chondrocytes are located
lacunae
[macroscopic type of bone]
core of spongy bone surrounded completely by compact bone
Short bones
principal function is heat-production by non-shivering thermogenesis
brown adipose tissue
Gives metabolic support to the cells as the medium for diffusion of nutrients and products
Connective tissues
always associated with dense connective tissue
Fibrocartilage
provides a shock-absorbing and sliding area for joints and facilitates bone movements
cartilage
Six (6) specialized connective tissues
Reticular tissue
Mucoid tissue
Adipose tissue
Cartilage
Bone
Blood
perforate the lamellae
Perforating canals / Volkmann canals
[type of cells]
synthesize the organic components of the matrix
Osteoblasts
[type of cartilage]
- most common and best studied
- bluish-white and translucent
- found in nose, tracheal rings, and where the ribs joins the sternum
Hyaline cartilage
Main constituent of connective tissue
Extracellular matrix (ECM)
also called as white fat
white adipose tissue
[type of cartilage]
- similar to hyaline cartilage, but it contains an abundant network of fine elastic fibers
- yellowish color
- found in the auricle of the ear walls, auditory tubes, epiglottis, and cuneiform cartilage
Elastic cartilage
Less flexible and far more resistant to stress
Dense connective tissue
Immune / defense functions
Lymphocytes
Eight (8) hemapoietic stem cells
Erythrocytes
Neutrophils
Eosinophils
Basophils
Mast cells
Megakaryocytes
Lymphocytes
Monocytes / Macrophages
adipose tissue:
men:
women:
men: 15-20%
women: 20-25%
- allows the tissue to bear mechanical stresses without permanent distortion
- essential for the development and growth of long bones
Cartilage
Has a delicate consistecy, flexible, well vascularized, and very resistant to stress
Loose connective tissue
Responsible for providing and maintaining the form of organs throughout the body
connective tissues
Extracellular fibers and ground substance
Fibroblasts
other name for reticular tissue
reticulin
[microscopic type of bone]
- found in adults with multiple layers of calcified matrix
- organized, either parallel to each other or concentrically around a vascular canal
Secondary / Lamellar bone
Derived from monocytes and penetrates the connective tissue
Macrophages
form sparse network interspersed with collagen bundles in many organs subject to much bending or stretching
Elastic fibers
three (3) types of cartilage
hyaline
elastic
fibrocartilage
Two (2) types of connective tissues
Embryonic
Adult
Provide the architectural framework that creates special microenvironments for hematopoietic organs and lymphoid organs
Reticular tissue
Segregation and digestion of foreign bodies
Multinuclear giant cell
other name for adipose tissue
lipocytes / fat cells
Consist mainly of collagen type III
Reticular fibers
Precursor of macrophages
Monocyte
serve as a supportive stroma in most lymphoid and hematopoietic organs & many endocrine organs
reticular fibers
other term for epiphyses
pineal
other name for elastic fibers
lamellae sheets
Formed by proteins that polymerize into elongated structures
Connective tissue fibers
[type of cartilage]
mixture of hyaline cartilage and connective tissue
Fibrocartilage
Stabilizes the ECM by binding the receptor proteins
Ground substance
Six (6) mesenchymal cells
Endothelial cells
Smooth muscle cells
Osteoblasts
Chondroblasts
Fibroblasts
Adipocytes
Types of connective tissues
Embryonic:
Mesenchyme
Mucous
Derived from B-lymphocytes
Responsible for synthesis of antibodies
Plasma cells
Modulate allergic reactions and defense against parasites
Eosinophilic leukocytes
three (3) types of cells
osteocytes
osteoblasts
osteoclasts