Congenital infx

Question 1

congenital CMV infx has what 3 signs at birth and what is the MC sequelae?

Answer 1

periventricular calcifications
microcephaly
thrombocytopenia
hearing loss = MC sequelae

Question 2

Congenital HSV infx has what 6 signs?

Answer 2

1. mucocutaneous vesicles/scarring
2. CSF pleocytosis
3. elevated liver enzymes
4. Thrombocytopenia
5. conjunctivitis/keratitis
6. seizures

Question 3

Congenital Rubella infx has what 5 signs? Which 3 are the classic triad?

Answer 3

1. ocular: catarcts, galucoma, retinopathy
2. Heart dz: PDA or pulmonary artery stenosis
3. radiolucent bone disease
4. hearing loss
5. microcephaly
   Classic = 1,2,4

Question 4

Congenital syphilis infx has what 5 signs? jaundice

Answer 4

1. skeletal abnormalities (elevated periosteum)
2. pseudoparalysis
3. persistent rhinitis
4. rash on soles and palms
5. jaundice

Question 5

Congenital toxoplasmosis infx has what 4 signs? Which 3 are the classic triad?

Answer 5

1. diffuse intracranial calcifications
2. hydrocephalus
3. chorioretinitis
4. mononuclear CSF pleocytosis or high CSF protein

Classic triad = #1-3

Question 6

Congenital Varicella infx has what 2 signs?

Answer 6

1. skin lesions

2. limb hypoplasia

Question 7

what may be the only clinical finding in toxo

Answer 7

chorioretinitis

Question 8

treatment of severe CMV?

Answer 8

gangcyclovir

Question 9

what is the classic retinal sign seen in rubella infx and it typically results when infx is in what time period?

Answer 9

Salt and pepper changes

< 8 weeks

Question 10

What do you do when the baby is born with HIV?

Answer 10

Start zidovudine within 6-12 hours after birth
Add nevirapine as soon as possible in high risk infants
(defined as mother who received only intrapartum ART,