12- CNS Infectious diseases, Dementias/Movement Disorders

Question 1

MC bacteria to cause infx of CNS

Answer 1

staph and strep

Question 2

what are the 2 Angioinvasive fungi that cause meningitis and what are the 2 differences between them

Answer 2

-Aspergillus: Septate, 45-degree branching

Mucor: non-septate; 90-degree branching

Question 3

diff between fungal and bacterial meningtis CSF findigns

Answer 3

fungal = lymphocytes
bacteria = neutrrophils

Question 4

how does toxoplasmosis meningitis look micro:

Answer 4

clusters of bradyzoites are known as tissue cysts

Question 5

What are 2 the classic histologic features in viral CNS infections?

Answer 5

1. perivascular lymphocytes 2. microglial nodules (clusters of glial cells)

Question 6

Cowdry A intranuclear (only) inclusions- - indx infx with what organism? is usually found where in brain? is seen in what pop?

Answer 6

HSV; found in anterior temporal and inferior frontal; seen i nadults

Question 7

CMV infx of CNS shows what micro? how different from HSV? what population?

Answer 7

Cowdry A intranuclear inclusions AND cytoplasmic inclusions; infants and adults

HSV is only intranuclear

Question 8

rabies infx micro findings? in what 2 locations?

Answer 8

Negri bodies in the hippocampus and Purkinje cells of the cerebellum;

Question 9

rabies CP? (20

Answer 9

CNS excitability and hydrophobia (contracture of pharyngeal muscles

Question 10

What is the MC viral meningitis dt?

Answer 10

coxsackie