Conditions Flashcards
What is TORCH?
Congenital/Neonatal infections
- toxoplasmosis
- other (syphilis, parvovirus, VZV, HIV, HBV)
- Rubella
- CMV
- HSV
Management of TORCH?
Toxoplasmosis - pyrimethamine + sulfadiazine + prednisolone
Other,syphilis - IM benzathine penicillin
Other,parvovirus - self-limiting
Other, VZV - acyclovir
Other, HIV - cord clamped, no breastfeeding, immunisations, zidovudine mono therapy
Other, HBV - vaccination
Rubella - no effective treatment, cardiac scans and hearing tests
CMV - ganiclovir
HSV - acyclovir
What is group B streptococcus?
Common in both men and women lives in the rectum or vagina, normally harmless.
In neonates:
pneumonia, meningitis and septicaemia in the neonate
Management of group B strep?
<72 HOURS -IV cefotaxime + amikacin + ampicillin
> 72 hours - IV meropenem + amikacin + ampicillin
What is Listeria monocytogenes
Cause of neonatal sepsis
mother has mild influenza and passes it to baby via placenta
can cause spontaneous abortion, neonatal sepsis
Symptoms of listeria monocytogenes?
meconium staining of liquor in pre-term infant, widespread rash, sepsis, pneumonia, meningitis
o Mortality 30%
Management of Listeria Monocytogenes
IV amoxicillin/ampiciliin
What is Kawasaki Disease?
Systemic Vasculitis 6m to 4 years old.
Japanese and black-carribean
uncommon
unknown cause
Signs and symptoms of Kawasaki disease?
C Conjunctivitis R Rash A Adenopathy (cervical l ymphadenopathy) S Strawberry tongue H Hands & feet swollen
o Burn Fever >5 days (not responsive to antipyretics)
Investigations for Kawasaki disease?
Diagnosis on clinical findings (no test)
o FBC (inc. platelets), CRP, ESR
o Echocardiography
Management for Kawasaki disease?
complications?
admission
IVIG + high dose aspirin (thrombosis)
corticosteroids, infliximab and plasmapheresis
Complications - children with coronary aneurysms may need warfarin
